DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9822 and PI16

DIOPT Version :9

Sequence 1:	NP_611581.1	Gene:	CG9822 / 37440	FlyBaseID:	FBgn0034623	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	225	Identity:	54/225 - (24%)
Similarity:	77/225 - (34%)	Gaps:	68/225 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 HESCS-----------------PDATMVDLKPYRKLIVNEHNKRRNYIASGSLPGYYPATRMATM 95
            |.|||                 |...:.|.:  ::|:|..||..|..::.       .|:.|..|
Human     2 HGSCSFLMLLLPLLLLLVATTGPVGALTDEE--KRLMVELHNLYRAQVSP-------TASDMLHM 57

  Fly    96 VWDEELEYLATLNLKTCYLEHDDCHNSYRFRNLGQNLC-----GVDRRRNWDLNVTNLVEQSMGL 155
            .|||||...|....:.|...    ||..|.|. |:||.     |:|            |..:|..
Human    58 RWDEELAAFAKAYARQCVWG----HNKERGRR-GENLFAITDEGMD------------VPLAMEE 105

  Fly   156 WFGEHKLIDSSYITDFKLTKDLEKYGHFVETVLDRNTHVGCAM--------MRFTNPQYPFLYIY 212
            |..|.:..:.|..|    ....:..||:.:.|..:...:||..        :..||       |.
Human   106 WHHEREHYNLSAAT----CSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETN-------IE 159

  Fly   213 NTACNYASVYAI-GVPVYNAGKPASECRTG 241
            ...|||.....: |...|..|.|.|:|.:|
Human   160 LLVCNYEPPGNVKGKRPYQEGTPCSQCPSG 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9822	NP_611581.1	SCP_euk	64..219	CDD:240180	40/167 (24%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	40/167 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920