DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NCR3LG1 and zgc:123297

DIOPT Version :9

Sequence 1:	NP_001189368.1	Gene:	NCR3LG1 / 374383	HGNCID:	42400	Length:	454	Species:	Homo sapiens
Sequence 2:	NP_001032650.1	Gene:	zgc:123297 / 641563	ZFINID:	ZDB-GENE-051127-9	Length:	318	Species:	Danio rerio

Alignment Length:	159	Identity:	42/159 - (26%)
Similarity:	72/159 - (45%)	Gaps:	42/159 - (26%)

- Green bases have known domain annotations that are detailed below.

Human    40 LNDNVTIFCNIFYSQP-LNITSMGITWFWKSLTFDKEVKVFEFFGDHQ-------EAFRPGA-IV 95
            :.|:|.:.|:   .:| :::..|.:.|....|. |..|.::|   ||:       |::|... ::
Zfish    35 VGDDVILPCS---GKPNISVVDMRVEWRRSDLK-DSLVHLYE---DHEDRETEQNESYRGRTQLI 92

Human    96 SPWRLKSGDASLRLPGIQLEEAGEYRCEVVVTPLKAQGTVQLEVVA------------SPASRLL 148
            .| .|:.|:|||||..:::.:.|.|:|.:.....|.:.||.|.|.|            :|:..|.
Zfish    93 HP-ELQRGNASLRLSSVKVSDEGRYKCIIGSESSKHEATVDLTVEALGWPPVITIDGFNPSGGLR 156

Human   149 LDQVGMKENEDKYMCESSGFYPEAINITW 177
            |            .|||.|:|||. ::.|
Zfish   157 L------------QCESEGWYPEP-HLEW 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NCR3LG1	NP_001189368.1	Ig	42..135	CDD:325142	26/101 (26%)
		Interaction with NCR3. /evidence=ECO:0000269\|PubMed:19528259	59..62		0/2 (0%)
		Ig	105..240	CDD:325142	25/85 (29%)
		Interaction with NCR3. /evidence=ECO:0000269\|PubMed:19528259	127..130		0/2 (0%)
		Retroviral-Gag-like	291..429
		Gag_MA	296..>377	CDD:307339
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	395..454
zgc:123297	NP_001032650.1	IG_like	33..135	CDD:214653	29/107 (27%)
		Ig	36..135	CDD:299845	29/106 (27%)
		Ig	141..224	CDD:299845	11/45 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.870