DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and AVT6

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_011044.1	Gene:	AVT6 / 856855	SGDID:	S000000921	Length:	448	Species:	Saccharomyces cerevisiae

Alignment Length:	454	Identity:	115/454 - (25%)
Similarity:	199/454 - (43%)	Gaps:	103/454 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRR--SFEMLGL 70
            |:||.::..|.||||||:.|:..|::..::::||        |......||..:.|  .:...|.
Yeast     9 VLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVL--------CGACAMQSLFIQARVAKYVPQGR 65

  Fly    71 HAFGTSGKLL-------VELCIIGYLIGTCITYFVVVGDLGPQIIA----KIFALDVADHLHLRS 124
            .:|....:|:       .:|.|.....|..::|.:|||||.|||::    ..:.|:       |:
Yeast    66 ASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRNAWLLN-------RN 123

  Fly   125 LVMVVVTVVCIVPLGMLRNVDSL---SAVCTASIGFYVCLILKIVLEAQPHITANDWTEKVL--- 183
            :.:.::.:..:.||..|:.::||   |.|..:|:. |:|:::.:      |..|.  ::::|
Yeast   124 VQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVA-YLCVLVLL------HYVAP--SDEILRLK 179

  Fly   184 ----YWEP-----AGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVR---NATWICTFV 236
                |..|     ..||..||||..|.:|...:|.:   ||.|...:...:::   .|..:...:
Yeast   180 GRISYLLPPQSHDLNVLNTLPIFVFAYTCHHNMFSI---INEQRSSRFEHVMKIPLIAISLALIL 241

  Fly   237 YISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYRKG 301
            ||::|..||:.|..:.. |||::....:..|.|.:|..||.:..:|||...|.|||::.:|....
Yeast   242 YIAIGCAGYLTFGDNII-GNIIMLYPQAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFA 305

  Fly   302 H----------------TESSS------------------YIPEQ------RFRFITIFIVVFSL 326
            .                ||||.                  |.|::      .|..||..|:|.|.
Yeast   306 EENVSISATSADEPTVATESSPLIRDSSLDLNEVIEEESIYQPKETPLRGKSFIVITCSILVASY 370

  Fly   327 CVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKII---KKESMERTLAQFVFVSGFLLMILG 387
            .||:.:.|:..::.:||:|...:|..:.|.....|:|   .|.::..|...|.: :|.||.|.|
Yeast   371 LVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHKTAVPLTTKIFKY-TGLLLFIWG 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	115/454 (25%)
		SLC5-6-like_sbd	8..390	CDD:294310	115/454 (25%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
AVT6	NP_011044.1	Aa_trans	1..439	CDD:279788	115/454 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H105685
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4114
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840