DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and AVT2

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_010850.1	Gene:	AVT2 / 856645	SGDID:	S000000790	Length:	480	Species:	Saccharomyces cerevisiae

Alignment Length:	395	Identity:	101/395 - (25%)
Similarity:	190/395 - (48%)	Gaps:	21/395 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 MTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHAF 73
            |.|||||:|.||:..||..:..|||..::..|....|.......::....|..:|:::....|..
Yeast    74 MNLANSILGAGIITQPFAIKNAGILGGLLSYVALGFIVDWTLRLIVINLTLAGKRTYQGTVEHVM 138

  Fly    74 GTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVAD-HLHL-RSLVMVVVTVVCIV 136
            |..||||:......:..|.||.|.:::||..|.::..||:.:..: |..| |::::|:||.....
Yeast   139 GKKGKLLILFTNGLFAFGGCIGYCIIIGDTIPHVLRAIFSQNDGNVHFWLRRNVIIVMVTTFISF 203

  Fly   137 PLGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQ--PHITANDWTEKVL----YWEPAGVLQCLP 195
            ||.|.||:::||.....::...:.::|.:|:...  |:    ||....|    ::..|.:.:.|.
Yeast   204 PLSMKRNIEALSKASFLAVISMIIIVLTVVIRGPMLPY----DWKGHSLKLSDFFMKATIFRSLS 264

  Fly   196 IFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFVYISVGFFGYVAFCTHTFSGNILVN 260
            :.|.||.|......:|.|:.|:|:.|...:...:..|.......:|:.|:..|...| .||:|.:
Yeast   265 VISFALVCHHNTSFIFFSMRNRSVAKFTRLTHISIIISVICCALMGYSGFAVFKEKT-KGNVLNS 328

  Fly   261 L-STSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYR----KGHTESSSYIPEQRFRFITIF 320
            . .|....:|.::.|..::..:||:.||..|..:.:||:.    |.:.|.:....:|.. .||..
Yeast   329 FPGTDTAINIARLCFGFNMLTTFPMEIFVLRDVVGNLLHECNLIKNYDEHTQLSGKQHV-VITSS 392

  Fly   321 IVVFSLCVALVIPSVELIIGLVGSTIGVAIC-IMFPASSFRKIIKKESMERTLAQFVFVS-GFLL 383
            :|..::.::|...::..:..|:|:|....:. |:.|.::.....||:|.:..|..::.:. ||::
Yeast   393 LVFITMGISLTTCNLGALFELIGATTASTMAYILPPYTNLLLTSKKKSWKERLPFYLCICFGFMI 457

  Fly   384 MILGT 388
            ||:.:
Yeast   458 MIISS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	101/395 (26%)
		SLC5-6-like_sbd	8..390	CDD:294310	101/395 (26%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
AVT2	NP_010850.1	Aa_trans	65..467	CDD:279788	101/395 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810