DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and AVT3

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_012776.1	Gene:	AVT3 / 853710	SGDID:	S000001629	Length:	692	Species:	Saccharomyces cerevisiae

Alignment Length:	442	Identity:	99/442 - (22%)
Similarity:	169/442 - (38%)	Gaps:	113/442 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 HSAH---------VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLL 59
            |..|         |:.|..|.:|.|:|.:|..|...|...| .|.:||..:....|.    .||:
Yeast   290 HGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFS-ALCLLSCALISYGCF----VSLI 349

  Fly    60 TRRRSFEMLGLHAFGTSGKLL----VELCIIGYL----IGTCITYFVVVGDLGPQIIAKIFALDV 116
            |.:   :.:|:..:|..|::|    ::..|:..:    ||....|.|... ...|:.::.|
Yeast   350 TTK---DKVGVDGYGDMGRILYGPKMKFAILSSIALSQIGFSAAYTVFTA-TNLQVFSENF---- 406

  Fly   117 ADHLHLR----SLVMVVVTVVCI-VPLGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQPHITAN 176
               .||:    ||...:...|.| |||.:.||:..||.....:..|.:..::.:.:.:..:|..|
Yeast   407 ---FHLKPGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYSIYYIAVN 468

  Fly   177 -------------DWT----EKVLYWEPAGVLQCLPI---------FSMALSCQMQLFEVFESIN 215
                         ||:    ..:..:|..|:|  :||         |..:||..|.:..|
Yeast   469 GVASDTMLMFNKADWSLFIGTAIFTFEGIGLL--IPIQESMKHPKHFRPSLSAVMCIVAV----- 526

  Fly   216 NQSLDKLNGIVRNATWICTFVYISVGFFGYVAFCTHTFSGN-----ILVNL--STSFGSDIIKIG 273
                                ::||.|...|.||      |:     :|:|.  .||: :..:::.
Yeast   527 --------------------IFISCGLLCYAAF------GSDVKTVVLLNFPQDTSY-TLTVQLL 564

  Fly   274 FVLSIAFSFPLVIFPCRASLYSLLYRKGHTESSSYIPEQRF--RFITIFIVVFSLCVALV-IPSV 335
            :.|:|..|.||.:||....|.:..:..  ..|..|.|:.::  .:....|||.:..:|.| ...:
Yeast   565 YALAILLSTPLQLFPAIRILENWTFPS--NASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDL 627

  Fly   336 ELIIGLVGSTIGVAICIMFPASSFRK--IIKKESMERTLAQ-FVFVSGFLLM 384
            :..:.||||...:.:..::|.....|  |:...|..|.|.. .|.|.|..:|
Yeast   628 DKFVSLVGSFACIPLIYIYPPLLHYKASILSGTSRARLLLDLIVIVFGVAVM 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	97/429 (23%)
		SLC5-6-like_sbd	8..390	CDD:294310	97/429 (23%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
AVT3	NP_012776.1	Aa_trans	295..687	CDD:279788	97/437 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810