DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and AVT1

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_012534.1	Gene:	AVT1 / 853457	SGDID:	S000003761	Length:	602	Species:	Saccharomyces cerevisiae

Alignment Length:	418	Identity:	95/418 - (22%)
Similarity:	163/418 - (38%)	Gaps:	51/418 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLAHSAHVMTLANSI---IGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRR 62
            :...|....|:.|||   ||:|:||:|...:..|.::.:.:|.:. .:...|...|:...|.|..
Yeast   204 LAGQSTAPQTIFNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIF-ALATFCTAELLSRCLDTDP 267

  Fly    63 R--SFEMLGLHAFGTSGKLLVELCIIGYLIGTCITYFVVVGD----LGPQIIAKIFALDVADHLH 121
            .  |:..||..||||.|:.|:.......|:|:.::..::.||    |.||.....|.:
Yeast   268 TLISYADLGYAAFGTKGRALISALFTLDLLGSGVSLVILFGDSLNALFPQYSTTFFKI------- 325

  Fly   122 LRSLVMVVVTVVCIVPLGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQPHITANDWTEKVLYWE 186
               :...:||....:||.:|.|:..|..:.|......:| ...:...:.|....|.....:  |
Yeast   326 ---VSFFIVTPPVFIPLSVLSNISLLGILSTTGTVLVIC-CCGLYKSSSPGSLVNPMETSM--W- 383

  Fly   187 PAGVLQ-CLPIFSMALSCQMQLFEVFESINN--QSLDKLNGIVRNATWICTFVYISVGFFGYVAF 248
            |..:.. ||.|  ..||.......||.::..  :..||....::....|.:...|.....|::.|
Yeast   384 PIDLKHLCLSI--GLLSACWGGHAVFPNLKTDMRHPDKFKDCLKTTYKITSVTDIGTAVIGFLMF 446

  Fly   249 CTHTFSGN-----ILVNLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRA----SLYSLLYRKGH-T 303
                  ||     |..|:..:.|......|.:.::....|:...|..|    |:..:|....| .
Yeast   447 ------GNLVKDEITKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDVLMNVQHID 505

  Fly   304 ESSSYIPEQRFR----FITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKIIK 364
            |::|.|..:..:    |..|||.|..:.:|:..|..:.||..:|:.:...||::.|...:.::.|
Yeast   506 EAASAIKRRAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTICLILPCWFYLRLCK 570

  Fly   365 K--ESMERTLAQFVFVSGFLLMILGTYA 390
            .  :..||...........:|..||..|
Yeast   571 TTIKPWERVACHVTICISVVLSTLGVGA 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	94/411 (23%)
		SLC5-6-like_sbd	8..390	CDD:294310	93/409 (23%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
AVT1	NP_012534.1	Aa_trans	206..601	CDD:279788	95/416 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810