DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30394 and AVT5

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_009464.2	Gene:	AVT5 / 852189	SGDID:	S000000185	Length:	459	Species:	Saccharomyces cerevisiae

Alignment Length:	464	Identity:	122/464 - (26%)
Similarity:	204/464 - (43%)	Gaps:	97/464 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVC--CHYLIKTSLL-----TRRRSF 65
            |:||.::..|.|:|||||.|:..|::..::.|....    :|  |..|::|.:.     :...||
Yeast     9 VLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCG----ICSLCGLLLQTRIAKYVPKSENASF 69

  Fly    66 EMLGLHAFGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIF-------ALDVADHLHL- 122
            ..| ......|..::.:..|.....|..::|.::||||.|||:..||       :.....|:.|
Yeast    70 AKL-TQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLD 133

  Fly   123 RSLVMVVVTVVCIVPLGMLRNVDSL---SAVCTASIGFYVCLILKIVLEAQPHITANDWTEK--V 182
            |.|.:.::.|..|.||...|:::||   |.:...|:.:...||:.       |.......|:  |
Yeast   134 RRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIY-------HFVNRHQLERGQV 191

  Fly   183 LYWEPAG------VLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRN----ATWICTFVY 237
            .:..|.|      .|..||||..|.:|...:|    |:.|:.:||...::|.    |..:..|:|
Yeast   192 YFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMF----SVINEQVDKSFKVIRRIPIFAIVLAYFLY 252

  Fly   238 ISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLL----- 297
            |.:|..||:.| .....||||.....|..:.|.::..:|.:..:|||...|||:|:.:::
Yeast   253 IIIGGTGYMTF-GENIVGNILTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIEN 316

  Fly   298 YRKG--HTESSSYIPEQRF---------------------------RFITIFIVVFSLCVALVIP 333
            :|||  :...:|:||...|                           ..||:.|::||..:|:.|.
Yeast   317 FRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISIT 381

  Fly   334 SVELIIGLVGSTIGVAICIMFPASSFRKIIKKE---SMERT---------LAQFVFVSGFLLMIL 386
            |:..::.:||:|...:|..:.|.....|:|..|   :.||.         |:..:|:.|..:|:
Yeast   382 SLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMV- 445

  Fly   387 GTYANLSAI 395
               |:||||
Yeast   446 ---ASLSAI 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	118/459 (26%)
		SLC5-6-like_sbd	8..390	CDD:294310	117/457 (26%)
		DUF4775	<394..652	CDD:292620	2/2 (100%)
		YukC	<561..660	CDD:295067
AVT5	NP_009464.2	Aa_trans	1..445	CDD:279788	116/452 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4114
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840