DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Slc32a1

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_113970.1	Gene:	Slc32a1 / 83612	RGDID:	621402	Length:	525	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	95/429 - (22%)
Similarity:	174/429 - (40%)	Gaps:	91/429 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCH--YLIKTSLLTRRRSFEMLGLH-- 71
            :.|:|.|:.:|.:|:.....| .|.:.|::.:   ..|||:  .::...|.......|::.:.
  Rat   125 VTNAIQGMFVLGLPYAILHGG-YLGLFLIIFA---AVVCCYTGKILIACLYEENEDGEVVRVRDS 185

  Fly    72 -----------AFGTSGKLLVELCIIGYLIGTCITYFVVVGDL------GPQIIAKIFALDVADH 119
                       .|.|.|..:|.:..|..|:.|||.|.||.|:|      |..:..|.::
  Rat   186 YVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQKSWS------ 244

  Fly   120 LHLRSLVMVVVTVVCIVPLGMLRN---VDSLSAVCTASIGFYVCLILKIVLEAQPHITANDWT-E 180
                    ::.|.| ::|...|:|   |...|.:||.:     ..::.|::.|.....|.||. |
  Rat   245 --------IIATAV-LLPCAFLKNLKAVSKFSLLCTLA-----HFVINILVIAYCLSRARDWAWE 295

  Fly   181 KVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNAT-------WICTFVYI 238
            ||.::        :.:....:|..:.:|.....|   .|..|.|.::..:       |......:
  Rat   296 KVKFY--------IDVKKFPISIGIIVFSYTSQI---FLPSLEGNMQQPSEFHCMMNWTHIAACV 349

  Fly   239 SVGFFGYVAFCTHTFSGNILV--NLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYRKG 301
            ..|.|..||:.|.......::  ||..|..: ::.|..|.....|:||..|.....|...|:::|
  Rat   350 LKGLFALVAYLTWADETKEVITDNLPGSIRA-VVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEG 413

  Fly   302 HTESSSYIP-----EQRFR----FITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPAS 357
               |.::.|     :.|.:    .:...:|||:|.:|:.:|...|::||.||..|..:|.:.|:.
  Rat   414 ---SRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSL 475

  Fly   358 SFRKIIKKESMER----TLAQFVF-----VSGFLLMILG 387
            ...:::.::.:..    .:|.||.     ||||:..:.|
  Rat   476 FHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEG 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	95/429 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	95/429 (22%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
Slc32a1	NP_113970.1	Aa_trans	115..512	CDD:279788	94/425 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810