DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Slc38a3

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001186146.1	Gene:	Slc38a3 / 76257	MGIID:	1923507	Length:	505	Species:	Mus musculus

Alignment Length:	441	Identity:	93/441 - (21%)
Similarity:	186/441 - (42%)	Gaps:	88/441 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHA 72
            |..|:|:|:|.|||.:.:.....||:|.:.||.....::....|.|:|:|.:...|::|.||..|
Mouse    71 VFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRA 135

  Fly    73 FGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQII---------AKIFALDVADHLHLRSLVMV 128
            |||.|||...|.|....||...:|..::....|.:|         |.::.:|       .:.:::
Mouse   136 FGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPASVWYMD-------GNYLVI 193

  Fly   129 VVTVVCIVPLGMLRNVDSLSAVCTASIGFYVCLILKIV--------------------------- 166
            :|:|..|:||.::|.:..|......|:...|..::.::
Mouse   194 LVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLANATGNFSHMVVA 258

  Fly   167 -----LEAQPHITANDWTEKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIV 226
                 |:.:|...|..:.....:...:.....:||.:.|..|..::..::..:.:.|..|:..|.
Mouse   259 EEKAQLQGEPDTAAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQHIS 323

  Fly   227 RNATWICTFVYISVGFFGYVAF-------CTHTFSG----NILVNLSTSFGSDIIKIGFVLSIAF 280
            ..:..:...:|.....|||:.|       ..||:|.    ::|:.        .:::..::::..
Mouse   324 NLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLIL--------CVRVAVLIAVTL 380

  Fly   281 SFPLVIFPCRASLYSLLYRKGHTESSSYIPEQRFRFITIFIVVFSL--CVALVI---PSVELIIG 340
            :.|:|:||.|.::..:|::           .|.|.::...::...|  |:.|::   |::..|.|
Mouse   381 TVPIVLFPVRRAIQQMLFQ-----------NQEFSWLRHVLIATGLLTCINLLVIFAPNILGIFG 434

  Fly   341 LVGSTIGVAICIMFPASSFRKIIKKE-----SMERTLAQFVFVSGFLLMIL 386
            ::|:|....:..:|||..:.:|:..:     |..:.||......|||||.:
Mouse   435 IIGATSAPCLIFIFPAIFYFRIMPTDKEPARSTPKILALCFAAVGFLLMTM 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	93/441 (21%)
		SLC5-6-like_sbd	8..390	CDD:294310	93/441 (21%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
Slc38a3	NP_001186146.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..48
Slc38a3	NP_001186146.1	Aa_trans	63..492	CDD:279788	93/441 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810