DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and slc38a5b

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001002648.1	Gene:	slc38a5b / 436921	ZFINID:	ZDB-GENE-040718-395	Length:	472	Species:	Danio rerio

Alignment Length:	451	Identity:	102/451 - (22%)
Similarity:	192/451 - (42%)	Gaps:	91/451 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHA 72
            |..|:|:|:|.|||.:.:.....||:|.:|||.....::....|.|::::.:...|::|.||..|
Zfish    54 VFNLSNAIMGSGILGLSYAMSNTGIVLFLVLLTCIAVLSSYSVHLLLRSAGVVGIRAYEQLGKRA 118

  Fly    73 FGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLR-------SLVMVVV 130
            ||..||:|..:.|..:.||...:|..:|....|.:|.....|.     |..       :.::::|
Zfish   119 FGHPGKILAAVVITMHNIGAMSSYLFIVKYELPLVIQAFLGLQ-----HSSGEWFLNGNYLIIIV 178

  Fly   131 TVVCIVPLGMLRNVDSLSAV----CTASIGFYVCLILK--------------------IVLEAQ- 170
            ::..|:||.::|.:..|...    .|..:.|.:.:|.|                    .::|.:
Zfish   179 SISIILPLALMRQLGYLGYTSGFSLTCMVFFLISVIYKKFNIPCPFEDFSNHTVVSNISIIEGEC 243

  Fly   171 --PHITANDWTEKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWIC 233
              ...|.|..|           ...:||.:.|..|..::..::..:.|.:..::..|. |.:.:.
Zfish   244 EAKFFTINQQT-----------AYTVPILAFAFVCHPEVLPIYTELRNPTKRRMQAIA-NVSILG 296

  Fly   234 TFV-YISVGFFGYVAFCTHTFSGNILVNLSTSFGSD----IIKIGFVLSIAFSFPLVIFPCRASL 293
            .|| |:....|||:.|..:| ...:|...|.....|    .:::..::::..:.|:|:||.|.:|
Zfish   297 MFVMYLLTAIFGYLTFYLNT-EAELLHTYSKVDPLDTLILCVRVAVLVAVTLTVPVVLFPIRRAL 360

  Fly   294 YSLLYRKGHTESSSYIPEQRF---RFITIFIVVFSLCVALV-------IPSVELIIGLVGSTIGV 348
            ..||:           ||:.|   |.|:|     :||:..|       :|::..|.|::|:|...
Zfish   361 LQLLF-----------PEKPFHWARHISI-----ALCLLFVVNLLVIFVPNIRDIFGIIGATSAP 409

  Fly   349 AICIMFPASSFRKIIKKE-----SMERTLAQFVFVSGFLLMILG-TYANLSAI--DEKSSG 401
            ::..:.|...:.:|:..|     |..:.||......||:.|.:. |:..|..:  :.:|.|
Zfish   410 SLIFILPGLFYIRIVSPEQEPMNSRPKILAACFTALGFIFMTMSLTFITLDWVYGENRSGG 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	99/438 (23%)
		SLC5-6-like_sbd	8..390	CDD:294310	99/436 (23%)
		DUF4775	<394..652	CDD:292620	2/10 (20%)
		YukC	<561..660	CDD:295067
slc38a5b	NP_001002648.1	SLC5-6-like_sbd	46..457	CDD:294310	99/436 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810