DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and CG43693

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	95/440 - (21%)
Similarity:	176/440 - (40%)	Gaps:	86/440 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTS-LLTRRRSFEMLG----- 69
            |....:|.||||||..|...|:...:|.......:...|.|.|:|.: :|.|||...|:|
  Fly   169 LLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRRKIPMMGFADVA 233

  Fly    70 ----------LHAFGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLRS 124
                      |:.:....:.:|...::..|:|.|..|.|.|.....|:: :::   :...|.:|.
  Fly   234 EQAFLDGPPALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVV-RVY---METELSIRV 294

  Fly   125 LVMVV---VTVVCIV-------PLGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQPHITANDWT 179
            .:|:|   :..:|:|       |..|:.|:.....:....|  |:...:...:|....::..:|
  Fly   295 WIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFI--YMFSDIPAPVERPGIVSVTEW- 356

  Fly   180 EKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLN--------GIVRNATWICTFV 236
                           |:|...:...::...|..|:.|   |..|        .::.....:...:
  Fly   357 ---------------PLFFGTVIFALEGIGVVMSLEN---DMKNPSHFIGCPSVLNFGMGLVIAL 403

  Fly   237 YISVGFFGYVAFCTHTFSGNILVNLSTSFG-SDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYRK 300
            |..|||||::.:...| ..:|.:||..... :..:|:...::|.|:|.|..:.....|:..|..|
  Fly   404 YTLVGFFGFLKYGPET-QASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKGLEHK 467

  Fly   301 GHTESSSYIPEQRFRFITIFIVVFSLCVALVIPSVELIIGLVG----STIGVAICIMFPASSFRK 361
            ...|..: |.|...|   :|:|:....:|:.:|::...|.|:|    ||:|:.:    ||:....
  Fly   468 IRPEKQN-ISEYGLR---VFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIV----PATIELA 524

  Fly   362 IIKKE--------SMERTLAQFVF-VSGFLLMILGTYANLSAID-EKSSG 401
            :..::        .:.:.....:| |.||   :.|||.::.... |.|||
  Fly   525 VYHEDPGYGRFNWRLWKNSGLILFGVVGF---VAGTYVSIIEFHAEFSSG 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	91/428 (21%)
		SLC5-6-like_sbd	8..390	CDD:294310	90/426 (21%)
		DUF4775	<394..652	CDD:292620	4/9 (44%)
		YukC	<561..660	CDD:295067
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	91/428 (21%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	91/429 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910