DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30394 and path

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001261634.1	Gene:	path / 39106	FlyBaseID:	FBgn0036007	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	93/428 - (21%)
Similarity:	175/428 - (40%)	Gaps:	62/428 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKT--SLLTRRRSFEML----- 68
            |..:.:|.|||.|||.|...|:::.|...:.:..|...|.:.|:|.  .|..|.|..:|.
  Fly    67 LLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRRTKMTFAEIA 131

  Fly    69 ---------GLHAFGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLRS 124
                     ....|....|..:...:.....|||..|.|:|.....|:|:......|:    ||.
  Fly   132 EAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTAVS----LRM 192

  Fly   125 LV-MVVVTVVCIVPLGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQPHITANDWTEKVLYWEPA 188
            |: :::|.::.|..:..|:.:..:|.|....:|..:.:....:::..|.:   :..|.|: |...
  Fly   193 LICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQDLPPV---EERESVV-WSTL 253

  Fly   189 GVLQCLPIFSM-ALSCQMQLFEVFESINN----QSLDKLNGIVRNATWICTFVYISVGFFGYVAF 248
            .....:.||:| |:...|.|      .||    ||...:.|::.......|.:|:.:||.||:.:
  Fly   254 PQFFSITIFAMEAIGVVMPL------ENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRY 312

  Fly   249 CTHTFSGNILVNLS-TSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYRKGHTESSSYIPEQ 312
            .:.| ..:|.:||. ..:.:..:|:...|::..:|.|..|.|...::.     |..|.....|..
  Fly   313 GSAT-GESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWD-----GIKEKCKKRPTL 371

  Fly   313 RFRFITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPA---------SSFRK---IIKK 365
            ....:...:|..::.:|:.:|::...:||:|:.....:.::||.         |.|.|   |:.|
  Fly   372 VNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFGKYNWILWK 436

  Fly   366 ESMERTLAQFVFVSGFLLMILGTYANLSAIDEKSSGPE 403
            .::       :.:.|...::.||.|.:..|.:..|..|
  Fly   437 NAI-------ITLCGIGALVFGTQAAIKDIVKAYSNNE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	90/415 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	89/413 (22%)
		DUF4775	<394..652	CDD:292620	3/10 (30%)
		YukC	<561..660	CDD:295067
path	NP_001261634.1	SLC5-6-like_sbd	56..456	CDD:294310	90/415 (22%)
path	NP_001261634.1	SdaC	67..445	CDD:223884	86/404 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4715
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860