DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and CG4991

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	95/429 - (22%)
Similarity:	175/429 - (40%)	Gaps:	84/429 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCH---YLIKTSLL---------------TRR 62
            :|.|:.||..||:..|:..:.:||.:   |..:|.|   .||:.|:|               |..
  Fly    98 VGAGLFAMGDCFKNGGLAGATILLPI---IAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVE 159

  Fly    63 RSFE--MLGLHAFGTSGKLLVE--LCIIGYLIGTCITYFVVVGDLGPQIIAK---IFALDVADHL 120
            :.||  ...|.......||:||  ||:..:  |.|..|||.:.:...|::.:   :.::
  Fly   160 KCFEHGPRPLRKMSRVMKLIVEMFLCVTQF--GFCAIYFVFITENLHQVLQQNGIVISM------ 216

  Fly   121 HLRSLVMVVVTVVCIVPLGM--LRNVDSLSAVCTASIGFYVCLILKIVLEAQPHITAND------ 177
               |:||::..:..::|..|  |:.:..:|.....::.|.:...|.|.....|..:..|
  Fly   217 ---SMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRHLFTG 278

  Fly   178 WTEKVLYWEPA-----GVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFVY 237
            ..:..|::..|     |:...||     |...|:..|.|.:        ..|::.:..:..|.::
  Fly   279 GAQLALFFGTALFSYEGIALILP-----LRNSMRRPEKFST--------RFGVLNSTMFFTTALF 330

  Fly   238 ISVGFFGYVAFCTHTFSGNILVNLST-SFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYRKG 301
            |..||..||.: ....:|:|.:||.. ...|.::|:...|.:...:|:..|.....|:..|.|..
  Fly   331 IFTGFVSYVRW-GEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSN 394

  Fly   302 HTESSSYIPEQ---RFRFITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKII 363
            :......|..|   ||     |:|:.:..||||:|.:.|.|.|:|:.  .:.|:.|........:
  Fly   395 NCTQKYPITSQVCLRF-----FMVMMTFGVALVVPKLNLFISLIGAL--CSTCLAFVIPVLIDFV 452

  Fly   364 KKESMERTLAQFVFVSGFLLM-------ILGTYANLSAI 395
            .:..:.:.|..:.::...|::       :.|||.::..|
  Fly   453 TRAQVPKALGVWSYIKNILILTVAVLGIVTGTYQSIVEI 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	94/424 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	93/422 (22%)
		DUF4775	<394..652	CDD:292620	1/2 (50%)
		YukC	<561..660	CDD:295067
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	94/425 (22%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	94/424 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468288
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940