DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and CG16700

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	90/429 - (20%)
Similarity:	181/429 - (42%)	Gaps:	71/429 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTR----------- 61
            ::.|....||.|:.||...|:..|:|::.:|.|:...::..|.|.|:..|...|
  Fly    60 IVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADY 124

  Fly    62 ----RRSFEMLGLHAFG---TSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADH 119
                .:.||.......|   |.|: ||::.|....:|.|..|||.:.....||:.   |.|:..:
  Fly   125 AQTVEQCFENGPSKLRGWSRTMGR-LVDIFICVTQLGFCCIYFVFISTNLKQILQ---AYDIDMN 185

  Fly   120 LHLRSLVMVVVTVVCIVPLGMLRNVDSLSAVCTASIGFYVCLILKIVL-------EAQPHITAND 177
            :||       |.::..||:.:...:.:|..:...|:...||:||.:.:       :..|.:....
  Fly   186 VHL-------VMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDGLPEVEERA 243

  Fly   178 -WT---EKVLYWEPA-----GVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWIC 233
             ||   :..|::..|     |:...:|     |...|:....||        :..|::....::.
  Fly   244 LWTNGSQLALFFGTAIFAFEGIALVMP-----LKNAMRKPHQFE--------RPLGVLNVGMFLV 295

  Fly   234 TFVYISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLY 298
            :.:::..|..||:.: .....|::.:||..:..:..:|:.....:...:||..|.....::....
  Fly   296 SVMFMFAGSVGYMKW-GEQVGGSLTLNLGDTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAK 359

  Fly   299 RKGHTESSSYIPEQRFRFITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKII 363
            :....|..|.:.|..||   .|:|:.:|.:|.::|::.|.|.|:|:....|:.::||  ...::|
  Fly   360 QMCGIEGRSLLGELGFR---TFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFP--PVIELI 419

  Fly   364 KKESMERTLAQFVFVSGFLLMIL-------GTYANLSAI 395
            .:..:.:....::.|...::::|       |:|.:|..|
  Fly   420 SRSELNKGPGIWICVKNLVILVLALLGFFTGSYESLKQI 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	88/424 (21%)
		SLC5-6-like_sbd	8..390	CDD:294310	87/422 (21%)
		DUF4775	<394..652	CDD:292620	1/2 (50%)
		YukC	<561..660	CDD:295067
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	87/421 (21%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	87/421 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840