DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30394 and CG32081

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	98/451 - (21%)
Similarity:	191/451 - (42%)	Gaps:	94/451 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TLANSIIGVGILAMPFCFQKCGILLSIVLLV-----LSNGITR-VCCHYLIKTSLLTRR-----R 63
            :|...::|.|::|:|..|...||:..|:|||     |.:|:.. :.|  :|:.|   ||     .
  Fly    27 SLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIIC--MIECS---RRMQIGYA 86

  Fly    64 SFEMLGLHAF----------GTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVAD 118
            ::.:..:::|          ..:|:.:|:..:.....|.|:.|.|.|.....|::.  |...|||
  Fly    87 TYPVAMVYSFDQGPRFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVD--FYWVVAD 149

  Fly   119 HLHLRSLVMVVVTVVCIVPLGMLRNVDSLSAV-CTASIGFYV--CLILKIVLEAQPHITANDWTE 180
               ||  :.:.|..:|::|...:|.:..|... ..|||..|.  .|::..:....|.||..:
  Fly   150 ---LR--IYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYLFVDLPPITERN--- 206

  Fly   181 KVLYWEPAGVLQCLPIFSMALSCQMQLFEV--------FESINNQSLDKLN--GIVRNATWICTF 235
             :|:    |.:..:|:|     ..:.||.:        .|:...:....|.  ||:..|..:...
  Fly   207 -ILF----GRIDKIPLF-----FGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVII 261

  Fly   236 VYISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAF-SFPLVIFPCRASLYSLLYR 299
            .|::.|..||..:...| :|:|.:|:.|......:..||:.:..| ::||..|.....:.:..:.
  Fly   262 SYVTFGLMGYWRYGDET-AGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWN 325

  Fly   300 KGHTESSSYIPEQRFRFITIFIVVFSLCV-ALVIPSVELIIGLVGS-TIG---------VAICIM 353
            |.....::.:.|...|..|:.::    |: |::.|::..::.|||: ||.         :.||:.
  Fly   326 KNGDLPNAALKESILRACTVVLI----CITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLY 386

  Fly   354 FPA----SSFRKIIKKESMERTLAQFVFVSGFLLMILGTYANLSAI-------DEKSSGPE 403
            :|.    ...:.::.|:.       |..:.|.|:::.||..::..:       |..:.|||
  Fly   387 YPPEYNYGKLKWVLVKDI-------FYVIVGILILVQGTVFSIKDMISEWGGGDTTTGGPE 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	94/431 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	94/429 (22%)
		DUF4775	<394..652	CDD:292620	4/17 (24%)
		YukC	<561..660	CDD:295067
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	94/431 (22%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	92/424 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930