DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30394 and Slc36a4

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001101597.1	Gene:	Slc36a4 / 315439	RGDID:	1311528	Length:	500	Species:	Rattus norvegicus

Alignment Length:	460	Identity:	106/460 - (23%)
Similarity:	179/460 - (38%)	Gaps:	121/460 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTS-LLTRRRSFEMLG-- 69
            :|.|....||.|:|.:|...:..||:|..:.||....|:..|.|.|::.| .|.:|.....||
  Rat    62 LMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFKKSTLGYS 126

  Fly    70 --------------LHAFGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQI--------IAKIF 112
                          |......|:.:|:..::...:|.|..|.|.:.:...|:        :....
  Rat   127 DTVSFAMEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGLLETTVVVSN 191

  Fly   113 ALDVADHLHLRSLVMVVVTVVCIVPLGML----RNVDS---LSAVCTASIGFYVCLILKIVLEAQ 170
            :.|::.....|| |.:.|.::|.:||.:|    |.:.|   ||.:...|:...:.:|.:.|:.:.
  Rat   192 SSDLSQVCERRS-VDLRVYMLCFLPLLILLVFIRELKSLFVLSFLANISMAASLVIIYQYVVRSM 255

  Fly   171 PH-----ITANDWTEKVLYWEPA-----GVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGI 225
            |.     |.|. |.:..|::..|     |:...||     |..||:..:.|....|..:.
  Rat   256 PDPHNLPIVAG-WKKYPLFFGTAVFAFEGIGVVLP-----LENQMRESKRFPQALNIGMA----- 309

  Fly   226 VRNATWICTFVYISVGFFGYVAFCTHTFSGNILVNLST------------SFGSDIIKIGFVLSI 278
                  |.|.:|||:...||:.| .....|:|.:||..            |||     |....||
  Rat   310 ------IVTVLYISLATLGYMCF-RDEIKGSITLNLPQDMWLYQSVKILYSFG-----IFVTYSI 362

  Fly   279 AFSFPL-VIFPC-RASLYSLLYRKGHTESSSYIPEQRFRFITIF----IVVFSLCV-ALVIPSVE 336
            .|..|. :|.|. .|.|::                 :::.|..|    ::|...|. |::||.::
  Rat   363 QFYVPAEIIIPAVTARLHA-----------------KWKCICDFGIRSLLVSITCAGAVLIPRLD 410

  Fly   337 LIIGLVGSTIGVAICIMFP----ASSFRK-------IIKKESMERTLAQFVFVSGFLLMILGTYA 390
            ::|..||:.....:.::.|    ..:|.|       ::|..|:..|        ||:..:||||.
  Rat   411 IVISFVGAVSSSTLALILPPLVEILTFSKDHYNVWMVLKNISIAFT--------GFVGFLLGTYV 467

  Fly   391 NLSAI 395
            .:..|
  Rat   468 TVEEI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	105/455 (23%)
		SLC5-6-like_sbd	8..390	CDD:294310	104/453 (23%)
		DUF4775	<394..652	CDD:292620	1/2 (50%)
		YukC	<561..660	CDD:295067
Slc36a4	NP_001101597.1	SLC5-6-like_sbd	54..469	CDD:294310	105/455 (23%)
Slc36a4	NP_001101597.1	PotE	<223..477	CDD:223605	68/298 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810