DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30394 and Slc38a7

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001003705.1	Gene:	Slc38a7 / 291840	RGDID:	1303268	Length:	463	Species:	Rattus norvegicus

Alignment Length:	437	Identity:	106/437 - (24%)
Similarity:	181/437 - (41%)	Gaps:	81/437 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCG-------ILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSF 65
            |..:.|:.:|.|:|..|..|...|       :.:.:::.::|..:....|      |..:..|::
  Rat    57 VFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYC------SQASNERTY 115

  Fly    66 EMLGLHAFGTSGKL---LVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALD---------VAD 118
            :.:   .:...|||   |.|:.|..|..||||.:.:::||...:||| :.|.:         ..|
  Rat   116 QEV---VWAVCGKLTGVLCEIAIAVYTFGTCIAFLIIIGDQQDKIIA-VMAKEPDGASGSPWYTD 176

  Fly   119 HLHLRSLVMVVVTVVCIVP--LGMLRNVDSLSAVCTASIGFYV--CLILKIVLEAQPHITANDWT 179
            .....||...:..:...:|  :|..:...|||.|.|    :||  .:|:|.:           |.
  Rat   177 RKFTISLTAFLFILPLSIPKEIGFQKYASSLSVVGT----WYVTAIVIIKYI-----------WP 226

  Fly   180 EKV-----LYWEPA---GVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFV 236
            :|.     :...||   .|...:|.......|.:....||.|:....:....|:|..|..|...|
  Rat   227 DKEMRPGDILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPQVKTWGGVVTAAMVIALAV 291

  Fly   237 YISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIG-----FVLSIAFSFPLVIFPCRASLYSL 296
            |:..|..|::     ||...:..::..|:.|:.:.:.     .:||:..|:|::.|..||.:..|
  Rat   292 YMGTGICGFL-----TFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGL 351

  Fly   297 LYR-KGHTESSSYIPEQRFRFI-TIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSF 359
            ..| ||.........|:|.|.: |:...:.:|.:||.||.:..:|.::|   |:|.|.:|.....
  Rat   352 WLRYKGTPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIG---GLAACFIFIFPGL 413

  Fly   360 RKI-IKKESME--RTLAQFVFVS-GFLLMILG------TYANLSAID 396
            ..| .|...||  :..:.:..|| |.||:.||      |.||...:|
  Rat   414 CLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAFIFGQTTANAVFVD 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	104/431 (24%)
		SLC5-6-like_sbd	8..390	CDD:294310	103/429 (24%)
		DUF4775	<394..652	CDD:292620	1/3 (33%)
		YukC	<561..660	CDD:295067
Slc38a7	NP_001003705.1	SLC5-6-like_sbd	49..458	CDD:382020	105/433 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810