DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Slc36a2

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_647555.2	Gene:	Slc36a2 / 246235	RGDID:	620492	Length:	481	Species:	Rattus norvegicus

Alignment Length:	446	Identity:	99/446 - (22%)
Similarity:	180/446 - (40%)	Gaps:	102/446 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRR---SFEMLG--- 69
            |....:|.|||.:|...:..|||:..:.|::...|...|.|.|::.:.....|   .|...|
  Rat    61 LVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTV 125

  Fly    70 LHAFGTS-----------GKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLR 123
            :|...:|           |:.:|...:|...:|.|..|.|.:.|...|::..:.:..::  .|..
  Rat   126 MHGLASSPNTWLQSHAHWGRHVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTIS--CHKN 188

  Fly   124 SLVMVVVTV------VCIVP-LGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQ----------- 170
            ..|::..|:      :..:| ||:|..:.:|..:...|:...|.:::.:|:.||
  Rat   189 ETVVLTPTIDSRLYMLAFLPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIAQYIIQGIPDPSQ 253

  Fly   171 -PHITANDWTEKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESI------NNQSLD--KLNGIV 226
             |.:.:  |....|::..|       |||            ||||      .|:..|  :...|:
  Rat   254 LPLVAS--WKTYPLFFGTA-------IFS------------FESIGVVLPLENKMKDARRFPTIL 297

  Fly   227 RNATWICTFVYISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFPL------- 284
            .....|.|.:||::|..||:.| ......:|.:||...:....:|:.:|:.|..::.|
  Rat   298 SLGMSIITTLYIAIGALGYLRF-GDDIKASITLNLPNCWLYQSVKLLYVVGILCTYALQFYVPAE 361

  Fly   285 VIFPCRASLYSLLYRKGHTESSSYIPEQRFRF-----ITIFIVVFSLCVALVIPSVELIIGLVGS 344
            :|.|...|..|                :|:..     |.:.:|..:..:|::||.::|::.||||
  Rat   362 IIIPLAVSQVS----------------KRWALPVDLSIRLALVCLTCMLAILIPRLDLVLSLVGS 410

  Fly   345 TIGVAICIMFPASSFRKIIKKESME-RTLAQFVFVS--GFLLMILGTYANLSAIDE 397
            ....|:.::.|..........|.|. .|:.:...:|  ||:..::|||   .|:||
  Rat   411 VSSSALALIIPPLLEVTTYYGEGMSPLTITKDALISILGFMGFVVGTY---QALDE 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	96/439 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	95/437 (22%)
		DUF4775	<394..652	CDD:292620	3/4 (75%)
		YukC	<561..660	CDD:295067
Slc36a2	NP_647555.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..49
Slc36a2	NP_647555.2	SLC5-6-like_sbd	50..461	CDD:382020	96/442 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810