DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Slc36a3

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_758462.2	Gene:	Slc36a3 / 215332	MGIID:	2665001	Length:	477	Species:	Mus musculus

Alignment Length:	440	Identity:	106/440 - (24%)
Similarity:	190/440 - (43%)	Gaps:	84/440 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSL-LTRR--RSF---EMLG 69
            |..|.||.|.|.:|...:..|:|:..|.|:....:|..|...|:..:. ||:|  |||   |...
Mouse    59 LLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRLQRSFVNYEETT 123

  Fly    70 LHAFGTS-----------GKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKI-FALDVADHLHL 122
            :::..|.           |:.:|...:|...:|.|..||:.:.|...||:.:. |..:|..  ..
Mouse   124 MYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAHFTSNVCQ--PR 186

  Fly   123 RSLVMVVVT-----VVCIVP----LGMLRNVDSL---SAVCTASIGFYVCLILKIVLEAQPH--- 172
            :||||..:.     ::.|:|    |.:::|...|   |.:.|.:....:.||.:.:::...|
Mouse   187 QSLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEYLIQTPHHSNL 251

  Fly   173 -ITANDWTEKVLYWEPA-----GVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATW 231
             :.|| |...:|::..|     ||...||     |..||:..:.|.::....:.
Mouse   252 PLVAN-WKTFLLFFGTAIFTFEGVGMVLP-----LKSQMKSPQQFPAVLYLGMS----------- 299

  Fly   232 ICTFVYISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFPL-------VIFPC 289
            ...|:||.:|..||:.|.|.| ..:|.:||...:....:|:.:.:.|.|::.|       :|.|.
Mouse   300 FVIFLYICLGTLGYMKFGTDT-QASITLNLPICWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPY 363

  Fly   290 RASLYSLLYRKGHTESSSYIPEQRFRFITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMF 354
            ..|..|        |:.:...:...|...:.:..||   |::||.::|:|.||||....|:.|:.
Mouse   364 VVSRVS--------ENWALFVDLTVRTALVCLTCFS---AVLIPRLDLVISLVGSVSSSALAIII 417

  Fly   355 P-----ASSFRKIIKKESMERTLAQFVFVSGFLLMILGTYANLSAIDEKS 399
            |     |:.:.:.|...::.:.:  .:.:.|.|..:||||..|..:.:::
Mouse   418 PPLLEIATFYSENISCATIVKDI--MISILGLLGCVLGTYQALYEMTQQT 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	105/431 (24%)
		SLC5-6-like_sbd	8..390	CDD:294310	104/429 (24%)
		DUF4775	<394..652	CDD:292620	0/6 (0%)
		YukC	<561..660	CDD:295067
Slc36a3	NP_758462.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..43
Slc36a3	NP_758462.2	SLC5-6-like_sbd	52..458	CDD:382020	105/431 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810