DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Slc38a5

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_766067.2	Gene:	Slc38a5 / 209837	MGIID:	2148066	Length:	479	Species:	Mus musculus

Alignment Length:	433	Identity:	95/433 - (21%)
Similarity:	194/433 - (44%)	Gaps:	57/433 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHA 72
            |..|:|:|:|.|||.:.:.....|::..:.||:....::....|.|:..:.:...|::|.||..|
Mouse    64 VFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRA 128

  Fly    73 FGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLR-SLVMVVVTVVCIV 136
            ||.:||::|.:.|..:.:|...:|..::....|.:|.....:|......|: :|::::|:::.|:
Mouse   129 FGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIIL 193

  Fly   137 PLGMLRNV------DSLSAVCTASIGFYVCLILK------------IVLEAQ--PHITANDWTEK 181
            ||.:::::      .|||..|  .:.|.:.:|.|            .|:||:  |....|...|.
Mouse   194 PLALMKHLGYLGYTSSLSLTC--MLFFLISVIYKKFQIGCDVSHNDTVVEAEQAPLQAFNSSCEA 256

  Fly   182 VLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFVYISVGFFGYV 246
            .|:...:.:...:||.:.|..|..::..::..:...:..::..:...:......:|.....|||:
Mouse   257 ELFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPTQRRMQAVANMSIGAMFIMYGLTATFGYL 321

  Fly   247 AFCTHTFSGNILVNLSTSFGSD-----IIKIGFVLSIAFSFPLVIFPCRASLYSLLYRKGHTESS 306
                 ||...:...:...:..:     .:::..:|::..:.|:|:||.|.:|..||:
Mouse   322 -----TFYSTVKAEMLEMYTQEDMLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLF-------- 373

  Fly   307 SYIPEQRF---RFITIFIVVFSLCVALVI--PSVELIIGLVGSTIGVAICIMFPASSFRKIIKKE 366
               |.:.|   |.:.|.:::..|...|||  |::..|.|.:|||...::..:.|:..:.:|:..|
Mouse   374 ---PSKAFSWLRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPTE 435

  Fly   367 -----SMERTLAQFVFVSGFLLMILG---TYANLSAIDEKSSG 401
                 |..:..|....|.|.|.|.:.   .:||.:....:.||
Mouse   436 VEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSG 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	92/422 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	91/420 (22%)
		DUF4775	<394..652	CDD:292620	2/8 (25%)
		YukC	<561..660	CDD:295067
Slc38a5	NP_766067.2	SdaC	56..469	CDD:223884	92/422 (22%)
Slc38a5	NP_766067.2	SLC5-6-like_sbd	56..466	CDD:294310	91/419 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810