DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Y32F6A.4

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_505680.2	Gene:	Y32F6A.4 / 179456	WormBaseID:	WBGene00012529	Length:	519	Species:	Caenorhabditis elegans

Alignment Length:	492	Identity:	103/492 - (20%)
Similarity:	177/492 - (35%)	Gaps:	140/492 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYL-IKTSLLTR---------RRSF 65
            :...:.|.||:|:|....:......:::.|:..|:.....:.| :..::|..         |:.:
Worm    64 VVGDLAGGGIVALPTAIIQAEFWTGLIVCVILIGVVTYTAYVLGLSWNILLSTWPEYRHHCRKPY 128

  Fly    66 EMLGLHAFGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLRSLVMVVV 130
            ..:|..|.|.:.:|||.:||........:.|.::.   ...|:..|.|.   ...|:...:::::
Worm   129 PEIGGRAMGKTCQLLVSICIDVTQFMISVVYLLLA---SKNIMNMIIAF---SGTHISFCILILI 187

  Fly   131 TVVCIVPLGMLRN-VDSLSAVCTASIGFYVCLILKIVLEAQPHITANDWTEKVLYWEPAGVLQCL 194
            ...|::||..|:: .|...||..|.:.....:||.||             ..::.:........|
Worm   188 VATCLLPLCFLKSPQDFWWAVVIAMMTTSAAVILIIV-------------GSIIDYGKCAPFAKL 239

  Fly   195 PIF---SMALSCQMQLFEV-----FESINNQSLDKLNGIVRN---ATWICTFVYISVGFFGYVAF 248
            |.|   ::.||....||.|     |.:|.: .:.:.....|:   |..|..|:||.|...||:.:
Worm   240 PPFRTTNLFLSMGTLLFSVGGHSAFPTIQH-DMKQPKEFTRSVFLAFTIMAFMYIPVCIMGYLVY 303

  Fly   249 ----------------------------C--THTFSGNILV-------NLSTSFGSD--IIKIGF 274
                                        |  |.|...|.|:       ::...||..  |::.|.
Worm   304 GDSLRDSIIPSIQTVWIQQAINIMITVHCILTLTIVFNPLMQEVEELFHVPQRFGPKRAIVRTGI 368

  Fly   275 VLSIAF---SFPL-----------------VIFPCRASLYSLLYRKGHTESSSYIPEQ---RFRF 316
            ::::.|   |.|.                 ||.||...:|...|::  .|..:..|..   .:|.
Worm   369 MVAVVFVAESVPTFGPLLDLVGGSTLTLTSVIMPCLFYIYLNAYKR--KEEITGKPGNGPVGWRD 431

  Fly   317 ITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKIIKKESMERTLAQF---VFV 378
            :..|....:||:.::|    :||||:|..     |..|.|          .:|.|..||   .:|
Worm   432 VITFNQKPTLCICIII----MIIGLIGGG-----CATFSA----------IVELTTTQFNMPCYV 477

  Fly   379 SGF-----------LLMILGTYANLSAI-DEKSSGPE 403
            |.|           .....|||.|:|.. |.|.|.|:
Worm   478 SVFQHKPADNGTASQTNCCGTYQNVSIFSDGKCSDPQ 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	97/478 (20%)
		SLC5-6-like_sbd	8..390	CDD:294310	96/476 (20%)
		DUF4775	<394..652	CDD:292620	4/11 (36%)
		YukC	<561..660	CDD:295067
Y32F6A.4	NP_505680.2	SLC5-6-like_sbd	54..415	CDD:382020	72/372 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810