DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30394 and Slc38a4

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_570104.1	Gene:	Slc38a4 / 170573	RGDID:	621836	Length:	547	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	95/483 - (19%)
Similarity:	199/483 - (41%)	Gaps:	127/483 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHAFGT 75
            |:|:|:|.|||.:.:.....||:|.:::|:....::....|.|:||:.......:|.||..|||.
  Rat    84 LSNAIMGSGILGLSYAMANTGIVLFVIMLLTVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGW 148

  Fly    76 SGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVAD---HLHLRSLVMVVVTVVCIVP 137
            .||:...:.|....||...:|..::....|::|.....|:...   :|:...||: .|:|..|:|
  Rat   149 PGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRVFMGLEENTGEWYLNGNYLVL-FVSVGIILP 212

  Fly   138 LGMLRNVDSL------SAVCTASIGFYVCLI----------LKIVLEAQPHITAN---------- 176
            |.:|:|:..|      |..|..   |:|.::          |.::.....::|.|
  Rat   213 LSLLKNLGYLGYTSGFSLTCMV---FFVSVVIYKKFQIPCPLPVLDHNNGNLTFNNTLPMHVIML 274

  Fly   177 -------------DWTEKVLYWEPAGV-----------------------------------LQC 193
                         |:|.:    :|.|:                                   ...
  Rat   275 PNNSESTGMNFMVDYTHR----DPEGLDEKPAAGPLHGSGVEYEAHSGDKCQPKYFVFNSRTAYA 335

  Fly   194 LPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFVYISVGFFGYVAFC--------- 249
            :||.:.|..|..::..::..:.::|..|:..:...:......:|:....|||::|.
  Rat   336 IPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLSFYGEVEDELLH 400

  Fly   250 ----THTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYRKGHTESSSYIP 310
                .:||...:|          ::::..::::..:.|:|:||.|.|:.:||:           |
  Rat   401 AYSKVYTFDTALL----------MVRLAVLVAVTLTVPIVLFPIRTSVITLLF-----------P 444

  Fly   311 EQRFRFITIF-----IVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKIIKKESME- 369
            .:.|.::..|     |:..:..:.:::|:::.|.|.:|::....:..:.||:.:.|::|||.:.
  Rat   445 RRPFSWVKHFGIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAAFYLKLVKKEPLRS 509

  Fly   370 -RTLAQFVFVSGFLLMILGTYANLSAID 396
             :.:...||:...::.::|:.| |..||
  Rat   510 PQKIGALVFLVTGIIFMMGSMA-LIIID 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	92/477 (19%)
		SLC5-6-like_sbd	8..390	CDD:294310	91/475 (19%)
		DUF4775	<394..652	CDD:292620	2/3 (67%)
		YukC	<561..660	CDD:295067
Slc38a4	NP_570104.1	SLC5-6-like_sbd	73..535	CDD:382020	93/480 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810