DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and SLC36A2

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_861441.2	Gene:	SLC36A2 / 153201	HGNCID:	18762	Length:	483	Species:	Homo sapiens

Alignment Length:	453	Identity:	103/453 - (22%)
Similarity:	170/453 - (37%)	Gaps:	116/453 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRR---------SFE 66
            |....:|.|||.:|...:..|||:..:.|::...|...|.|.|:|.:....:|         ...
Human    63 LVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPFMDYGDTV 127

  Fly    67 MLGLHAFGTS--------GKLLVELCIIGYLIGTCITYFVVVGDLGPQII--------------A 109
            |.||.|...:        |:.:|...:|...:|.|..|.|.:.|...|::              .
Human   128 MHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNET 192

  Fly   110 KIFALDVADHLHLRSLVMVVVTVVCIVPLGMLRNVDSLSAVCTASIGFYVCLILKIVLEAQ---- 170
            .|....:...|::.|.:..:|.:|.|..|.:|.....|     |:|...|.|::.|....|
Human   193 VILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSML-----ANISMLVSLVIIIQYITQEIPD 252

  Fly   171 ----PHITANDWTEKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIV----- 226
                |.:.:  |....|::..|       |||            ||||         |:|
Human   253 PSRLPLVAS--WKTYPLFFGTA-------IFS------------FESI---------GVVLPLEN 287

  Fly   227 --RNATW----------ICTFVYISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIA 279
              :||..          |.|.:||.:...||:.| ......:|.:||...:....:|:.::..|.
Human   288 KMKNARHFPAILSLGMSIVTSLYIGMAALGYLRF-GDDIKASISLNLPNCWLYQSVKLLYIAGIL 351

  Fly   280 FSFPL-------VIFPCRASLYSLLYRKGHTESSSYIPEQRFRFITIFIVVFSLCVALVIPSVEL 337
            .::.|       :|.|...|..|..:......|           |.:.:|..:..:|::||.::|
Human   352 CTYALQFYVPAEIIIPFAISRVSTRWALPLDLS-----------IRLVMVCLTCLLAILIPRLDL 405

  Fly   338 IIGLVGSTIGVAICIMFPASSFRKIIKKESME-RTLAQFVFVS--GFLLMILGTYANLSAIDE 397
            :|.||||..|.|:.::.|..........|.|. .|:.:...:|  ||:..::|||   .|:||
Human   406 VISLVGSVSGTALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTY---QALDE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	100/446 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	99/444 (22%)
		DUF4775	<394..652	CDD:292620	3/4 (75%)
		YukC	<561..660	CDD:295067
SLC36A2	NP_861441.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..46
SLC36A2	NP_861441.2	SLC5-6-like_sbd	52..463	CDD:320982	100/449 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810