DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and SLC38A11

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001338466.1	Gene:	SLC38A11 / 151258	HGNCID:	26836	Length:	462	Species:	Homo sapiens

Alignment Length:	403	Identity:	95/403 - (23%)
Similarity:	180/403 - (44%)	Gaps:	36/403 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SAHVMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLG 69
            ||.:..:.|||||.||:.:|:..::.|..|.|:||...:.:|......|||...|:...:::.|.
Human    35 SAALFNVVNSIIGSGIIGLPYSMKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLV 99

  Fly    70 LHAFGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFALDVADHLHLRSLVMVVVTVVC 134
            ...||..|.||:.:....|.....|:|.::.||...::..:|..:|..:....|..::.:.||..
Human   100 NKTFGFPGYLLLSVLQFLYPFIAMISYNIIAGDTLSKVFQRIPGVDPENVFIGRHFIIGLSTVTF 164

  Fly   135 IVPLGMLRNVDSLSAVCTASIGFYVCLILKIV----LEAQPHITANDWTEKVLYWEPAGVLQCLP 195
            .:||.:.||:..|..|...|.|. ..|||.||    :...|||..   ||....:.....:|.:.
Human   165 TLPLSLYRNIAKLGKVSLISTGL-TTLILGIVMARAISLGPHIPK---TEDAWVFAKPNAIQAVG 225

  Fly   196 IFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFVYISVGFFGYVAFCTHTFSGNILVN 260
            :.|.|..|....|.|:.|:...::.|.:.::..:..|..|:.|.....||:.|...| .|::..|
Human   226 VMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFT-QGDLFEN 289

  Fly   261 LSTSFGSDIIKIG---FVLSIAFSFPLVIFPCRASLYSLLYRKGHTESSSYIPEQRFRFITIFIV 322
            ...:  .|::..|   :.:::..::|:..|..|..:.::.: .|:..|..:|      .:|:.::
Human   290 YCRN--DDLVTFGRFCYGVTVILTYPMECFVTREVIANVFF-GGNLSSVFHI------VVTVMVI 345

  Fly   323 VFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKIIKKESMERT------------LAQF 375
            ..:..|:|:|..:.:::.|.|......:..:.|::.:.|:.::   .||            :...
Human   346 TVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEE---PRTHSDKIMSCVMLPIGAV 407

  Fly   376 VFVSGFLLMILGT 388
            |.|.||::.|..|
Human   408 VMVFGFVMAITNT 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	93/400 (23%)
		SLC5-6-like_sbd	8..390	CDD:294310	93/400 (23%)
		DUF4775	<394..652	CDD:292620
		YukC	<561..660	CDD:295067
SLC38A11	NP_001338466.1	SLC5-6-like_sbd	37..418	CDD:320982	91/397 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810