DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and Slc38a1

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001159928.1	Gene:	Slc38a1 / 105727	MGIID:	2145895	Length:	485	Species:	Mus musculus

Alignment Length:	440	Identity:	104/440 - (23%)
Similarity:	192/440 - (43%)	Gaps:	76/440 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHA 72
            |..|:|:|:|.|||.:.|.....||||.::||.....::....:.|:..|..|....:|.||...
Mouse    77 VFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQV 141

  Fly    73 FGTSGKLLVELCIIGYLIGTCITY-FVVVGDLGPQIIAKIFALDVADHLHLRSLVMVV-VTVVCI 135
            |||:|||::.........|..::| |:|..:|...|.:.:...|.....::...|:|| ||...|
Mouse   142 FGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEDAFSAWYVDGRVLVVMVTFGII 206

  Fly   136 VPLGMLRNVDSLSAVCTASIG----FYVCLILK------IVLEAQPHITAN----------DWTE 180
            :||.:|:|:..|......|:.    |.:.:|.|      :.:|....::||          .:..
Mouse   207 LPLCLLKNLGYLGYTSGFSLSCMMFFLIVVIYKKFQTPCMSVEQNSTVSANVTDACTPKYVTFNS 271

  Fly   181 KVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICTFV-YISVGFFG 244
            |.:|        .||..:.|..|...:..::..:.::|..|:. :|.|.::...|| |.....||
Mouse   272 KTVY--------ALPTIAFAFVCHPSVLPIYSELKDRSQKKMQ-MVSNISFFAMFVMYFLTAIFG 327

  Fly   245 YVAF-------CTHTF--SGNILVNLSTSFGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYR- 299
            |:.|       ..|.:  :|:||:.        .:::..::::..:.|::.|..|:||:.|..:
Mouse   328 YLTFYEKVQSDLLHKYQSTGDILIL--------TVRLAVIVAVILTVPVLFFTVRSSLFELAKKT 384

  Fly   300 KGHTESSSYIPEQRFRFITIFIVVFSLCVALVIPSVELIIGLVGSTIGVAICIMFPASSFRKIIK 364
            |.|.        .|...:||.:::....:.:.|||::.|.|:||.|....:..:.|:|.:.||..
Mouse   385 KFHL--------CRHVLVTIILLIIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITN 441

  Fly   365 KESMERTLAQFVFVSGFLLMILGTYANLSAIDEKSSGPEFDMVAIGTPLY 414
            ::..:.|  |.::.:.||                ..|..|.:::|...:|
Mouse   442 QDGDKGT--QRIWAALFL----------------GLGVLFSLISIPLVIY 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	100/416 (24%)
		SLC5-6-like_sbd	8..390	CDD:294310	100/414 (24%)
		DUF4775	<394..652	CDD:292620	4/21 (19%)
		YukC	<561..660	CDD:295067
Slc38a1	NP_001159928.1	SLC5-6-like_sbd	69..472	CDD:382020	103/437 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840