DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30394 and slc38a5a

DIOPT Version :9

Sequence 1:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	XP_001344749.1	Gene:	slc38a5a / 100005797	ZFINID:	ZDB-GENE-081105-92	Length:	491	Species:	Danio rerio

Alignment Length:	443	Identity:	99/443 - (22%)
Similarity:	197/443 - (44%)	Gaps:	68/443 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRRSFEMLGLHA 72
            :..|:|:|:|.|||.:.:.....||:|.:.||:....::....|.|::::.:...|::|.||..|
Zfish    63 IFNLSNAIMGSGILGLAYAMANTGIILFVFLLITIALLSSYSIHLLLRSAGVVGIRAYEQLGYRA 127

  Fly    73 FGTSGKLLVELCIIGYLIGTCITYFVVVGDLGPQIIAKIFAL-DVADHLHLRSLVMVVVTVVCIV 136
            |||.||::....|..:.||...:|..:|....|.:|..:..| |.:.|.::....::::..||::
Zfish   128 FGTPGKVVAGCIITLHNIGAMSSYLFIVKIELPHVIEGLTGLPDNSGHWYVDGRYLIIIVSVCVI 192

  Fly   137 -PLGMLRNVDSLSAVCTASIGFYVCLILKIV--------------------------LEAQPHIT 174
             ||.:::.:..|......|:...|..::.::                          :.:...|.
Zfish   193 FPLALMKRLGYLGYTSGFSLSCMVFFLISVIYKCLSNSGIDSESNQNEKCTFSNASMISSTTEIN 257

  Fly   175 -ANDWTE----KVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINNQSLDKLNGIVRNATWICT 234
             .|..||    |:|...|.... .:||.:.|..|..::..::..:.|.|..::.. |.|.:.:..
Zfish   258 EINSTTEICEAKLLTINPQTAF-TIPIIAFAFVCHPEVLPIYTELKNPSKKQMQK-VANISILAM 320

  Fly   235 FV-YISVGFFGYVAFCTHTFSGNILVNLSTSFG-SDI----IKIGFVLSIAFSFPLVIFPCRASL 293
            || |:....|||:     ||..|:...|...:. :||    :::..::::..:.|:|:||.|.::
Zfish   321 FVMYLLTAIFGYL-----TFFANVDSELLKMYNKNDILMLCVRLAVLVAVTLTVPVVLFPIRRAV 380

  Fly   294 YSLLYRKGHTESSSYIPEQRFRFITIFIVVFSLCVA-----LVIPSVELIIGLVGSTIGVAICIM 353
            ..||:           ||:.|.::...|:...|..|     :.:|::..|.|.:|:|...::..:
Zfish   381 LQLLF-----------PEKPFSWVRHIIIAMCLLFAVNLLVIFVPNIRDIFGFIGATSAPSLIFI 434

  Fly   354 FPASSFRKIIKKE-----SMERTLAQFVFVSGFLLMILG-TYANLSAIDEKSS 400
            .|...:..|:.:|     |..:.||......||:.||:. |:..:..::.|.|
Zfish   435 LPGIFYIYIVPEEQEPLKSRPKILAILFVTLGFIFMIMSITFIIIEWVNGKQS 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	97/433 (22%)
		SLC5-6-like_sbd	8..390	CDD:294310	97/431 (23%)
		DUF4775	<394..652	CDD:292620	2/7 (29%)
		YukC	<561..660	CDD:295067
slc38a5a	XP_001344749.1	SdaC	55..479	CDD:223884	97/433 (22%)
slc38a5a	XP_001344749.1	SLC5-6-like_sbd	55..479	CDD:294310	97/433 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840