Protein Alignment CG9485 and agla

DIOPT Version :10

• Sequence 1: NP_726062.2
• Gene: CG9485 / 37435
• FlyBaseID: FBgn0034618
• Length: 1629
• Species: Drosophila melanogaster
• Sequence 2: XP_005163674.1
• Gene: agla / 567798
• ZFINID: ZDB-GENE-071004-6
• Length: 1533
• Species: Danio rerio
• Alignment Length: 1576
• Identity: 732/1576 - (46%)
• Similarity: 993/1576 - (63%)
• Gaps: 109/1576 - (6%)

  Fly   102 ISEGQDAEHILYRLKRGSKLSVHPDASLLGRKIVLYTNYPAEGQKFVRTEYRVLGWQLSNGKQIT 166
            :::.:..:..|:||.:|.:|......:|.|:.:.:|||||.||::|.|.::..|.|
Zfish    11 LNDMEKLDRTLFRLDQGFELQFRLGPTLQGKHVRVYTNYPTEGERFDRQKFHALDW--------- 66

  Fly   167 SVMHPEAHVVDTDIRSQVELNMSGTYHFYFRYLERPDTGCSGADGALYVQVEPTLHVGPPGAQKT 231
              ::|.|...|:|....::|.:||:|.:||.:      |.....|..|:.|:|.|.||  .....
Zfish    67 --INPTAREDDSDKFCTLDLKISGSYQYYFGH------GGDEKSGGGYIVVDPVLRVG--ADNHV 121

  Fly   232 IPLDSVRCQTVLAKLLGPLDTWEPKLRVAKEAGYNVIHFTPIQELGGSRSCYSLRDQLKVNSHFA 296
            :|||.:..||.|:|.|||||.|..:||||||||||:|||||:|.||.|||||||.|||::|..|:
Zfish   122 LPLDCITIQTYLSKCLGPLDEWSDRLRVAKEAGYNMIHFTPLQTLGESRSCYSLADQLELNPDFS 186

  Fly   297 PQKGGKISFEDVEKVIKKCRQEWGVASICDIVLNHTANESDWLLQHPDATYSCATCPYLRPAFLL 361
            | .|...::.|...:::|.:.||.:..|.|:|.||||:.|.|:.:||:..|:....|:|:||::|
Zfish   187 P-SGQTYTWTDAGNLVEKLKNEWNMLCITDVVYNHTASNSKWIKKHPECGYNLVNSPHLKPAWVL 250

  Fly   362 DATFAQCGADIAEGSLEHVGVPAVIEQECHLEALKYQLHTSYMSKVNIHELYQCDVMKYVNEFMS 426
            |.........||:|..|..|:||:|:...||.|::..|......|:.:.|.:|..:...|.:|.:
Zfish   251 DRALWHVTCAIADGKYEDRGLPALIQDHPHLHAIRGVLWQEVFPKIKLWEFFQVKIEALVEQFRA 315

  Fly   427 QVRTREPPKNVANECRFQEIQLIQDPQYRRLASTINFELALEIF--NAFHGDCFDEESRFRKCAE 489
            .:::...|.:...:.: :::::||||||||..:|::...|||:|  |.      :.......|..
Zfish   316 LLQSGAKPDSSKTDGK-KQLKIIQDPQYRRFGNTVDMNTALELFVPNG------NSPGAIEDCCN 373

  Fly   490 TLRRHLDALNDRVRCEVQGYINYAIDNVLAGVRYERVQGDGPRVKEISEKHSVFMVYFTHTGTQG 554
            .|||.|:.||.....||:.:...|.:.:...|.|||:...||::..|:.||.:...|||....:
Zfish   374 WLRRKLEELNGEQFHEVKHHQEQATNCIDGTVSYERLADHGPKLGPITRKHPLVTRYFTFPFEE- 437

  Fly   555 KSLTEIEADM----YTKAGEFFMAHNGWVMGYSDPLRDFAEEQPGRANVYLKRELISWGDSVKLR 615
               |.:|.|:    ..:....|:|||||||| .||||:|||  || :|||::||||.||||||||
Zfish   438 ---TTLEQDLELINQPEKSCHFLAHNGWVMG-DDPLRNFAE--PG-SNVYIRRELICWGDSVKLR 495

  Fly   616 FGRRPEDSPYLWQHMTEYVQTTARIFDGVRLDNCHSTPLHVAEYLLDAARKINPELYVVAELFTN 680
            :|..|||.||||.||.:|.:.||:.|.||||||||||||||||.:|.|||.:.|.|||:|||||.
Zfish   496 YGSGPEDCPYLWAHMQKYTEITAKHFVGVRLDNCHSTPLHVAEAMLAAARSVRPNLYVIAELFTG 560

  Fly   681 SDYTDNVFVNRLGITSLIREALSAWDSHEQGRLVYRYGGVPVGGFQANSSRHEATSVAHALFLDL 745
            |:..|||||||||||||||||:||.||||:|||||||||.|||.|...|.|....|:|||:|||:
Zfish   561 SELIDNVFVNRLGITSLIREAMSAGDSHEEGRLVYRYGGEPVGAFLQPSLRPLVPSIAHAMFLDV 625

  Fly   746 THDNPSPVEKRSVYDLLPSAALVSMACCATGSNRGYDELVPHHIHVVDEERTYQEWG-------- 802
            ||||..|::.|||||.|||:|:||||||||||.|||||||||.|.||.|||.|.:|.
Zfish   626 THDNECPIQIRSVYDSLPSSAIVSMACCATGSTRGYDELVPHQISVVSEERFYTKWSSQAKPSSP 690

  Fly   803 KGVDSKSGIMGAKRALNLLHGQLAEEGFSQVYVDQMDPNVVAVTRHSPITHQSVILVAHTAFGYP 867
            ..|:.::||:..|.|||.||.:||.:|||||:|||:|.::||||||.|.|||||:.|..|||..|
Zfish   691 NEVNLQTGIIAGKLALNRLHQELAAKGFSQVFVDQVDEDIVAVTRHCPSTHQSVVAVCRTAFKNP 755

  Fly   868 SPNAGPTGIRPLRFEGVLDEIILEASLTMQSDKPFDRPAPFKKDPNVINGFTQFQLNLQEHIPLA 932
            ..:.....:.|:...|.::|::|||....:      :...:|||...|||..::.:.::|||.||
Zfish   756 KHHRYTDEVPPMCIPGKIEEVVLEARTVER------QTGTYKKDERSINGMPEYTVEIKEHIQLA 814

  Fly   933 KSTVF-QTQAYSDGNN---TELNFANLRPGTVVAIRVSMHPGPRTSFDKLQKISAALR------- 986
            .|.|. |....|.|.:   .|:.|..|.||:|:|.|||:.|       |.|::...||
Zfish   815 DSKVVRQAGVTSRGRSEYVQEIVFEKLTPGSVIAFRVSLDP-------KSQELVGVLRNHLIQFN 872

  Fly   987 ----IGSGEE-------YSQLQAIVSKLDLVALSGALFSCDDEERDLGKGGTAYDIPNFGKIVYC 1040
                .||..:       .|.|..|:|||.|..::..||.||.||::  .||..|:||.:..:.|.
Zfish   873 PLYKAGSVPDSNTPDILKSPLTQIMSKLTLADMNLLLFRCDSEEKE--DGGGCYNIPGWTPLKYG 935

  Fly  1041 GLQGFISLLTEISPKNDLGHPLCNNLRDGNWMMDYISDRLTSY-EDLKPLSAWFKATFEPLKNIP 1104
            ||||.:|::.||.||||||||.|:|||.|:||:||:|:||.|. ..|..:..||:|.|..||:||
Zfish   936 GLQGLLSVMAEIRPKNDLGHPFCDNLRQGDWMIDYVSNRLVSRGGPLAEVGQWFQAMFAYLKHIP 1000

  Fly  1105 RYLIPCYFDAIVSGVYNVLINQVNELMPDFIKNGHSFPQSLALSTLQFLSVCKSANLPGFSPALS 1169
            |||||||||||:.|.:...::.....|..|:::|.||.:.|||.::|...|.:...||..|||||
Zfish  1001 RYLIPCYFDAILVGAFTTALDATFRQMSSFVQDGSSFVKLLALGSVQMCGVGRFPALPPLSPALS 1065

  Fly  1170 P--------PKPPKQ-CVTLSAGLPHFSTGYMRCWGRDTFIALRGSMFLTGRYNEARFIIIGFGQ 1225
            .        .|..:| ||:::|||||||.|..|||||||||||||.:.:|||:.|||.||:.|..
Zfish  1066 DVPYRVNEITKEKEQCCVSMAAGLPHFSAGIFRCWGRDTFIALRGLLLVTGRHLEARNIILAFAG 1130

  Fly  1226 TLRHGLIPNLLDSGSKPRFNCRDAIWWWMYCIKQYVEDAPKGAEILKDKVSRIFPYDDADAHAPG 1290
            |||||||||||..|...|||||||:|||:.||:.|....|.|.:||:..|||::|.||:.....|
Zfish  1131 TLRHGLIPNLLGEGVGARFNCRDAVWWWLQCIQDYCTMVPNGTDILQCPVSRMYPTDDSKPLTAG 1195

  Fly  1291 AFDQLLFDVMQEALQVHFQGLQYRERNAGYEIDAHMVDQGFNNQIGIHPETGFVFGGNNFNCGTW 1355
            ..||||::|:.||::.|.||:::||.|||.:||.:|.|:|||.:..::|:||||:|||.||||||
Zfish  1196 TVDQLLYEVIHEAMERHIQGIEFRESNAGPQIDRNMRDEGFNIEAKVNPDTGFVYGGNRFNCGTW 1260

  Fly  1356 MDKMGSSQKAGNKGRPSTPRDGSAVELVGLQYAVLRFMQSLAEKEVIPYTGV--ERKGPSGEVTK 1418
            |||||.|::|.|||.|:|||||||||:|||..:.||::..|.:|.:.||..|  :|.|....|
Zfish  1261 MDKMGESERARNKGIPATPRDGSAVEIVGLCKSTLRWLVELHKKGLFPYNTVKIQRDGKQLSV-- 1323

  Fly  1419 WSYKEWADRIKNNFDKYFFVS------ESETCSVANKKLIYKDSYGATQSWTDYQLRCNFPITLT 1477
             :|.||..:|:.||:|.|:||      ..:...:.:|:.||||||||:..|.|||||.||.|.:.
Zfish  1324 -AYDEWEMKIQKNFEKMFYVSHDPNDPNEKHPELVHKRGIYKDSYGASSPWCDYQLRPNFTIAMV 1387

  Fly  1478 VAPDLCNPQNAWRALERAKKYLLGPLGMKTMDPEDWNYRANYDNSNDSTDCTVAHGANYHQGPEW 1542
            |||:|...::||:||..|::.|||||||||:||:|..|...||||.|:.:..:|.|.||||||||
Zfish  1388 VAPELFTVEHAWKALNMAEEKLLGPLGMKTLDPDDMVYCGVYDNSLDNDNYNLAKGFNYHQGPEW 1452

  Fly  1543 VWPIGFYLRARLIFAKKCGH--LDETIAETWAILRAHLRELQTSHWRGLPELTNDNGSYCGDSCR 1605
            :||||::|||::.||||.|.  .|:|:.....:|..|...::.|.|:|||||||:||.||..||.
Zfish  1453 LWPIGYFLRAKIFFAKKMGKDTYDKTVYLVKNVLSRHNVHMERSSWKGLPELTNENGQYCSFSCE 1517

  Fly  1606 TQAWSVAAILEVLYDL 1621
            |||||:||:||||:||
Zfish  1518 TQAWSLAAVLEVLHDL 1533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9485	NP_726062.2	RNA_pol_I_A49	<30..>76	CDD:462024
		glyc_debranch	112..1621	CDD:273673	730/1564 (47%)
agla	XP_005163674.1	GDE_C	21..1533	CDD:481207	730/1564 (47%)