Protein Alignment CG9485 and agl-1

DIOPT Version :10

• Sequence 1: NP_726062.2
• Gene: CG9485 / 37435
• FlyBaseID: FBgn0034618
• Length: 1629
• Species: Drosophila melanogaster
• Sequence 2: NP_496984.1
• Gene: agl-1 / 175091
• WormBaseID: WBGene00011050
• Length: 1467
• Species: Caenorhabditis elegans
• Alignment Length: 1570
• Identity: 657/1570 - (41%)
• Similarity: 923/1570 - (58%)
• Gaps: 141/1570 - (8%)

  Fly    91 MGKETESHSIPISEGQDAEHILYRLKRGSKLSVHPDASLLGRKIVLYTNY-PAEGQKFVRTEYRV 154
            ||:|.|...|.:.:|:..|.::.::::|..:.....:||||:|:.::|:. |...
 Worm     1 MGEEKEIRIIVLEDGEHLESVIRKIEKGWIVRFKRGSSLLGKKVKVFTSICPGNS---------- 55

  Fly   155 LGWQLSNGKQITSVMHPEAHVVDTDIRSQVELNMSGTYHFYFRYLERPDTGCSGADGALYVQVEP 219
            |.|  |.||.         |:.   :..|||...:|::.::|:..:..:.| ||     |..|.|
 Worm    56 LEW--SEGKD---------HLA---VYCQVECKEAGSFRYWFKIEDSEERG-SG-----YFLVMP 100

  Fly   220 TLHVGPPGAQKTIPLDSVRCQTVLAKLLGPLDTWEPKLRVAKEAGYNVIHFTPIQELGGSRSCYS 284
            .|.:.    .|.:|||.:.|||.|.||||||..|:.:|.||.:.|||:||.|||.|||.|.|.||
 Worm   101 ELKIN----GKCLPLDGIACQTYLTKLLGPLSEWKERLEVAHQTGYNMIHLTPIHELGISNSSYS 161

  Fly   285 LRDQLKVNSHFAPQKGGKISFEDVEKVIKKCRQEWGVASICDIVLNHTANESDWLLQHPDATYSC 349
            |.|...:......| ..|..||||:.::....:.|.:.::.|:|.||.|..:.|||:||::.|:|
 Worm   162 LSDHHSLIKTIQSQ-DQKFGFEDVQALVGDLERSWNILTVQDVVWNHAAKNATWLLEHPESAYNC 225

  Fly   350 ATCPYLRPAFLLDATFAQCGADIAEGSLEHVGVPAVIEQECHLEALKYQLHTSYMSKVNIHELYQ 414
            ...|:||||:::|..:.:.|..|.||..||.|||.|::...|:.|::|.|....:.|.::||.||
 Worm   226 LNSPHLRPAYVIDRVYHEFGKQIGEGVWEHRGVPPVVDNIHHVNAIEYLLRAEVLPKADLHEFYQ 290

  Fly   415 CDVMKYVNEFMSQVRTREPPKNVANECRFQEIQLIQDPQYRRLASTINFELALEIFNAFHGDCFD 479
            .|:...||.|...::....|  ..|....:::::.||.:.||..:|::||.:..|||...||...
 Worm   291 VDLKAMVNLFEVFIKQSSGP--TTNPLDGEDVEIEQDLECRRFGNTVDFERSARIFNRHRGDAKS 353

  Fly   480 EESRFRKCAETLRRHLDALNDRVRCEVQGYINYAIDNVLAGVRYERVQGDGPRVKEISEKHSVFM 544
            ||.|..||..:....|:..|.....|....|...:..|:.|:.|||:..:||:...:|.::.:..
 Worm   354 EEERVEKCVRSFEEALNNKNLEAARESWEVILAGLAAVMGGITYERIADNGPKKGLVSPENPLTT 418

  Fly   545 VYFTHTGTQGKSLTEIEADMYTKAGE----------FFMAHNGWVMGYSDPLRDFAEEQPGRANV 599
            .||.|          :|||:..|:.|          |.||.|||||. |||:::||.::   :.|
 Worm   419 DYFLH----------LEADLGWKSEEKFAYDPEKSKFLMAFNGWVMS-SDPMKNFALKE---SQV 469

  Fly   600 YLKRELISWGDSVKLRFGRRPEDSPYLWQHMTEYVQTTARIFDGVRLDNCHSTPLHVAEYLLDAA 664
            ||:|||:.|||||||.:|.:..|||:|||:|.||.|..||||.|:|:||.|.||:||||.||..|
 Worm   470 YLRRELVCWGDSVKLNYGNKEADSPFLWQYMKEYTQQAARIFHGLRIDNAHGTPIHVAEKLLKTA 534

  Fly   665 RKINPELYVVAELFTNSDYTDNVFVNRLGITSLIREALSAWDSHEQGRLVYRYGGVPVGGFQANS 729
            |::.|::||.|||||.|::.||:|||||||:||||||.||.||||||||||||||..||.|:..|
 Worm   535 REVRPDIYVFAELFTGSEHADNMFVNRLGISSLIREAQSAHDSHEQGRLVYRYGGDCVGAFKQKS 599

  Fly   730 SRHEATSVAHALFLDLTHDNPSPVEKRSVYDLLPSAALVSMACCATGSNRGYDELVPHHIHVVDE 794
            :|....|:||.||||.:||||||:..||.:|:||:||:::||.||.|||||||||:..|||||.|
 Worm   600 ARLAPKSIAHGLFLDQSHDNPSPIHTRSPFDILPTAAMLTMASCAVGSNRGYDELIRDHIHVVSE 664

  Fly   795 ERTYQEWGK--GVDSKSGIMGAKRALNLLHGQLAEEGFSQVYVDQMDPNVVAVTRHSPITHQSVI 857
            :|.|..|.:  .|....||:..:..||.||..|||.|:|||:||||:.::|.:|||:|.||::|:
 Worm   665 KRPYASWCRPDQVSRSQGIIEGRNLLNKLHTWLAEHGYSQVFVDQMNSDIVGITRHNPRTHETVV 729

  Fly   858 LVAHTAFGYPSPN--AGPTGIRPLRFEGVLDEIILEASLTMQSDKPFDRPAPFKK--------DP 912
            :|:||:|   |.|  ..|.|::.:...|||:.:|.|..|              ||        ||
 Worm   730 VVSHTSF---SKNYIDWPGGLKHIPIGGVLENVIFEMKL--------------KKVQEEWGTEDP 777

  Fly   913 NVINGFTQFQLNLQEHIPLAKSTVFQTQAYSDGNNTELNFANLRPGTVVAIRVSMHPGPRTSFDK 977
            :|:.|...:::.::|::.|...|:|:..   ||   .:...|...|:||..::      |.| |:
 Worm   778 DVLIGLKNYEMEIRENVNLDNGTMFKVH---DG---YIELTNFPTGSVVGFKI------RPS-DE 829

  Fly   978 LQKISAALRIGSGEEYSQLQAIVSKLDLVALSGALFSCDDEE-RDLGKGGTAYDIPNFGKIVYCG 1041
            ..|....:......|.|:..:.:|:|...:....||.|:.|: ..:.:||  ||:|||||.||||
 Worm   830 ATKAFNMIHNSITPEQSEFDSALSRLTYQSFPNLLFHCESEDYATIQQGG--YDVPNFGKFVYCG 892

  Fly  1042 LQGFISLLTEISPKNDLGHPLCNNLRDGNWMMDYISDRLTSYEDLKPLSAWFKATFEPLKNIPRY 1106
            |||.:.:|.:|...||||||||.|||||.|:.|||..||..:|.|..:|...:..|.||.::|.|
 Worm   893 LQGLVPVLEKIRDDNDLGHPLCQNLRDGTWICDYIVGRLAKFEKLGEVSEAIRKFFAPLDHVPYY 957

  Fly  1107 LIPCYFDAIVSGVYNVLINQVNELMPDFIKNGHSFPQSLALSTLQFLSVCKSANLPGFSPALS-P 1170
            |.||||:.:||.:|..:..:..:.|...|.:..:..:.||:|||.||.....|.|.....:|. .
 Worm   958 LRPCYFELLVSYIYGKIRKEALKRMAPQISSSSALVRHLAISTLSFLGYIPGAGLAPIPTSLQIE 1022

  Fly  1171 PKPPKQCVTLSAGLPHFSTGYMRCWGRDTFIALRGSMFLTGRYNEARFIIIGFGQTLRHGLIPNL 1235
            .:.|.   :|:|||.||:.|..|.|||||||||.|.:..|||:.|||.||:.|...:||||||||
 Worm  1023 DQYPS---SLAAGLSHFAVGIWRNWGRDTFIALPGCLLSTGRFQEARQIILSFAGAIRHGLIPNL 1084

  Fly  1236 LDSGSKPRFNCRDAIWWWMYCIKQYVEDAPKGAEILKDKVSRIFPYDDADAHAPGAFDQLLFDVM 1300
            |..|...|:|||||.|:|:..|.:|||.||.|..||:|.|.||:|.||: .:..|...|:|.:.:
 Worm  1085 LAEGIGARYNCRDATWFWLVSIVKYVESAPNGVGILEDPVRRIYPNDDS-VYGEGEVQQMLIETI 1148

  Fly  1301 QEALQVHFQGLQYRERNAGYEIDAHMVDQGFNNQIGIHPETGFVFGGNNFNCGTWMDKMGSSQKA 1365
            .|||..||.|:.||||:||.:||..|.|:||....|:...|||::|||.:||||||||||||::|
 Worm  1149 YEALDKHFAGIDYRERSAGPQIDEQMRDEGFQVTAGVSRTTGFIYGGNRWNCGTWMDKMGSSERA 1213

  Fly  1366 GNKGRPSTPRDGSAVELVGLQYAVLRFMQSLAEKEVIPYTGVERKGPSGEVTKWSYKEWADRIKN 1430
            ||||.|:|||||:||||.||.|..|:.:::..|:.||     :|.|.|.|   |::..||.:|:.
 Worm  1214 GNKGEPATPRDGAAVELQGLAYRALKSLKNWKEQGVI-----QRSGVSDE---WTWGFWAQKIRE 1270

  Fly  1431 NFDKYFFVSESETCSVANKKLIYKDSYGATQSWTDYQLRCNFPITLTVAPDLCNPQNAWRALERA 1495
            ||:|.|||.:.......|::.|.|||.|:|..:||:||||||.|.|.|||||.:|:.||:||:.|
 Worm  1271 NFEKEFFVDKDSYAEFVNRREIIKDSVGSTLGFTDFQLRCNFGIALAVAPDLMDPKKAWKALDSA 1335

  Fly  1496 KKYLLGPLGMKTMDPEDWNYRANYDNSNDSTDCTVAHGANYHQGPEWVWPIGFYLRARLIFAKKC 1560
             :.|||||||||:||.||.|...|:|.:|.||...|.|.||||||||::..|:||:|||......
 Worm  1336 -EVLLGPLGMKTLDPTDWAYNGYYNNDDDGTDKKTAKGWNYHQGPEWLFVAGYYLQARLRIGDIL 1399

  Fly  1561 GHLDETIAETWAILRAHLRELQ-----------TSHWRGLPELTNDNGSYCGDSCRTQAWSVAAI 1614
            |..::..|         :|::|           :|.||.||||||.:|.||..||..|||||..:
 Worm  1400 GGSEKQYA---------IRQVQERLGNAYKHIISSPWRSLPELTNADGEYCMQSCAAQAWSVGCL 1455

  Fly  1615 LEVLYDLHSL 1624
            :|....|:::
 Worm  1456 IEACVKLNTI 1465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9485	NP_726062.2	RNA_pol_I_A49	<30..>76	CDD:462024
		glyc_debranch	112..1621	CDD:273673	649/1544 (42%)
agl-1	NP_496984.1	glyc_debranch	22..1462	CDD:273673	649/1544 (42%)