Protein Alignment Arms and mask

DIOPT Version :10

• Sequence 1: NP_726059.5
• Gene: Arms / 37433
• FlyBaseID: FBgn0261554
• Length: 1642
• Species: Drosophila melanogaster
• Sequence 2: NP_001247280.1
• Gene: mask / 50070
• FlyBaseID: FBgn0043884
• Length: 4010
• Species: Drosophila melanogaster
• Alignment Length: 714
• Identity: 191/714 - (26%)
• Similarity: 306/714 - (42%)
• Gaps: 164/714 - (22%)

  Fly     8 RKPQKRASIAEETPVSDSTTPATTASPSSPSRTAGHSTIGALVSNLHH-------HDIQSLHQP- 64
            :|.:..|:.|..:..:.|.|.:.:::.||.|.:||  .:.|:.|.|.:       .|.:...||
  Fly   341 QKLKDAAAAASASASNRSATSSMSSTASSLSSSAG--IVNAISSALQNIITPDTDTDTEFYPQPV 403

  Fly    65 ---LLESEE----RVIVA-----------VNHRNPRQ-PHRSYGTERKPHSSLPRFVINIEEETD 110
               |.||||    .:::|           :...:|.. ||.....|.:..:.        ||..|
  Fly   404 TTDLSESEEESVSEILLAFLCLRPDLLDDIPESDPDSCPHEGEVREDEDETE--------EESED 460

  Fly   111 AAVAAAEG-----------KSSPAPNQEHEEHSNQSPSRRFSHFNLAL--RRFSHIHA------- 155
            :..:..|.           :.:.|.::|.::...:..:...|.|.|..  :|.|:|.|
  Fly   461 SDESEGEEEEEDEEEIDVLQDNDADDEEIDDEDEEEDAPEVSSFLLDANNKRSSNISALLEAAAN 525

  Fly   156 ----------HNINRFGDSMGSLG-----------HRALLQYIDNNDISGLRAIL---------- 189
                      |.|:....::..:.           .|:|:....:||::.::.:|
  Fly   526 EKAPVLRHATHAIDETKQALTKMRCASSPRDKNGFSRSLVAACTDNDVNTVKRLLCKGNVNLNDA 590

  Fly   190 -----DSRHL----------------------TIDDRDENATTVLMVVAGRGLTAFVREFLARGA 227
                 |...|                      .::|:.:..:|.||..|..|....|:..|...|
  Fly   591 AASTDDGESLLSMACSAGYYELAQVLLAMSAAQVEDKGQKDSTPLMEAASAGHLDIVKLLLNHNA 655

  Fly   228 DVQAEDLDNWTALLCASRNGHLDVVQLLLDHGAEVEHRDMGGWTSLMWAAYRGHTELVRLLLDKG 292
            ||.|......|.|:.|...|.:|||::||.|||.||.::..|.|.||.||..||.|:.::||:.|
  Fly   656 DVNAHCATGNTPLMFACAGGQVDVVKVLLKHGANVEEQNENGHTPLMEAASAGHVEVAKVLLEHG 720

  Fly   293 ADGNAHGNY-------------HLG---------------------ALLWAAGRGYKDIVELLVQ 323
            |..|.|.|.             ||.                     ||:.|:..|:.::..||:.
  Fly   721 AGINTHSNEFKESALTLACYKGHLDMVRFLLQAGADQEHKTDEMHTALMEASMDGHVEVARLLLD 785

  Fly   324 RGAKVNV-GDKYGTTALVWACRRGNVEIVDTLLKAGANVDTAGMYSWTPLLVAAAGGHTDCVSSI 387
            .||:||: .|.:.:...:.|| .|:||:...|::.|||::......:|||:.||..||.:.|:.:
  Fly   786 SGAQVNMPTDSFESPLTLAAC-GGHVELATLLIERGANIEEVNDEGYTPLMEAAREGHEEMVALL 849

  Fly   388 LEKKPNVNALDKDGM-TALCIASREGFQDIAASLIAAGAYINIQDRGADTPLIHAVKAGHRTVVE 451
            |.|..|:||..::.. |||.:|...||.::||.||..||.:.:   ||.|||:.|.:.||..:|.
  Fly   850 LSKGANINATTEETQETALTLACCGGFMEVAAFLIKEGANLEL---GASTPLMEASQEGHTDLVS 911

  Fly   452 ALLKKHADVDIQGKDRKTAIYTAVEKGHTPIVKLLLATNPDLESATKDGDTPLLRAVRNRNLEIV 516
            .||||.|:|..:.:...||:..|.|.|||....:||:...:||..::.|.|||::|.|..:|..|
  Fly   912 FLLKKKANVHAETQTGDTALTHACENGHTDAAGVLLSYGAELEHESEGGRTPLMKACRAGHLCTV 976

  Fly   517 HLLLDRKAKVTASDKRGD-TCLHIAMRARSKTIVEALLRN---PKH-----SQLLYRANKAGET 571
            ..|:.:.|.|.......| |.|.:|.....:::||.||:|   |.|     |.:|..|:|.|.|
  Fly   977 KFLIQKGANVNKQTTSNDHTALSLACAGGHQSVVELLLKNNADPFHKLKDNSTMLIEASKGGHT 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arms	NP_726059.5	ANKYR	172..438	CDD:440430	98/338 (29%)
		ANK repeat	205..233	CDD:293786	11/27 (41%)
		ANK repeat	235..266	CDD:293786	14/30 (47%)
		ANK repeat	268..299	CDD:293786	14/30 (47%)
		ANK repeat	301..332	CDD:293786	12/65 (18%)
		ANKYR	316..598	CDD:440430	95/267 (36%)
		ANK repeat	334..362	CDD:293786	9/27 (33%)
		ANK repeat	367..398	CDD:293786	13/30 (43%)
		ANK repeat	400..431	CDD:293786	12/31 (39%)
		ANK repeat	435..464	CDD:293786	13/28 (46%)
		ANK repeat	466..497	CDD:293786	11/30 (37%)
		ANK repeat	499..530	CDD:293786	11/30 (37%)
		KAP_NTPase	605..1136	CDD:462231
		SAM_superfamily	1357..1392	CDD:188886
mask	NP_001247280.1	ANKYR	584..858	CDD:440430	77/274 (28%)
		ANK repeat	596..628	CDD:293786	3/31 (10%)
		ANK repeat	633..661	CDD:293786	11/27 (41%)
		ANK repeat	663..694	CDD:293786	14/30 (47%)
		ANK repeat	696..724	CDD:293786	13/27 (48%)
		ANK repeat	730..760	CDD:293786	2/29 (7%)
		ANKYR	744..1062	CDD:440430	100/301 (33%)
		ANK repeat	765..794	CDD:293786	10/28 (36%)
		ANK repeat	796..827	CDD:293786	9/31 (29%)
		ANK repeat	829..858	CDD:293786	11/28 (39%)
		ANK repeat	862..894	CDD:293786	12/34 (35%)
		ANK repeat	896..923	CDD:293786	13/26 (50%)
		ANK repeat	927..957	CDD:293786	11/29 (38%)
		ANK repeat	959..991	CDD:293786	11/31 (35%)
		ANK repeat	993..1023	CDD:293786	10/29 (34%)
		ANK	2321..2349	CDD:197603
		ANK repeat	2323..2352	CDD:293786
		ANKYR	2336..2623	CDD:440430
		ANK repeat	2354..2386	CDD:293786
		ANK repeat	2390..2419	CDD:293786
		ANK repeat	2421..2452	CDD:293786
		ANK repeat	2456..2486	CDD:293786
		ANK repeat	2492..2521	CDD:293786
		ANK repeat	2523..2589	CDD:293786
		ANK repeat	2560..2587	CDD:293786
		ANK repeat	2591..2622	CDD:293786
		KH-I_MASK	3047..3116	CDD:411832