DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42672 and Rfxank

DIOPT Version :9

Sequence 1:	NP_726059.5	Gene:	CG42672 / 37433	FlyBaseID:	FBgn0261554	Length:	1642	Species:	Drosophila melanogaster
Sequence 2:	NP_001013154.1	Gene:	Rfxank / 306353	RGDID:	1311390	Length:	284	Species:	Rattus norvegicus

Alignment Length:	210	Identity:	64/210 - (30%)
Similarity:	95/210 - (45%)	Gaps:	46/210 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 NDISGLRAILDSRHLTIDDRDENATTVLMVVAGRGLTAFVREFLARGADVQAEDLDNWTALLCAS 244
            |::|.|.|.|||  |:|..           :|.:|..:.:::.|.:|        ||.
  Rat   104 NEVSALPATLDS--LSIHQ-----------LAAQGELSQLKDHLRKG--------DNL------- 140

  Fly   245 RNGHLDVVQLLLDHGAEVEHRDMGGWTSLMWAAYRGHTELVRLLLDKGADGNAHGNYHLGALLWA 309
                             |...|..|:|.|:||:..|..|.||.|||.|||.:........||..|
  Rat   141 -----------------VNKPDERGFTPLIWASAFGEIETVRFLLDWGADPHILAKERESALSLA 188

  Fly   310 AGRGYKDIVELLVQRGAKVNVGDKYGTTALVWACRRGNVEIVDTLLKAGANVDTAGMYSWTPLLV 374
            :..||.|||.||:.|...:|:.|..|.|.|::|.|..:|:.|:.||..||::.|.....:||:.:
  Rat   189 SMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDL 253

  Fly   375 AAAGGHTDCVSSILE 389
            |.|.|:.. |..::|
  Rat   254 AVALGYRK-VQQVME 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42672	NP_726059.5	ANK	169..289	CDD:238125	26/108 (24%)
		Ank_2	173..266	CDD:289560	16/85 (19%)
		ANK repeat	205..233	CDD:293786	4/27 (15%)
		ANK	231..355	CDD:238125	39/123 (32%)
		ANK repeat	235..266	CDD:293786	3/30 (10%)
		Ank_2	240..332	CDD:289560	29/91 (32%)
		ANK repeat	268..299	CDD:293786	15/30 (50%)
		ANK repeat	301..332	CDD:293786	12/30 (40%)
		Ank_2	306..398	CDD:289560	31/84 (37%)
		ANK	329..454	CDD:238125	21/61 (34%)
		ANK repeat	334..362	CDD:293786	11/27 (41%)
		ANK repeat	367..398	CDD:293786	7/23 (30%)
		ANK repeat	400..431	CDD:293786
		Ank_4	401..454	CDD:290365
		ANK	428..553	CDD:238125
		ANK repeat	435..464	CDD:293786
		Ank_2	438..530	CDD:289560
		ANK repeat	466..497	CDD:293786
		ANK repeat	499..530	CDD:293786
		Ank_5	518..575	CDD:290568
		KAP_NTPase	605..1136	CDD:284995
		SAM_superfamily	1357..1392	CDD:188886
Rfxank	NP_001013154.1	ANKYR	89..271	CDD:223738	64/210 (30%)
		ANK repeat	118..145	CDD:293786	8/69 (12%)
		ANK repeat	147..178	CDD:293786	15/30 (50%)
		Ank_2	152..242	CDD:403870	37/89 (42%)
		ANK repeat	180..211	CDD:293786	12/30 (40%)
		ANK repeat	213..241	CDD:293786	11/27 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000