DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42672 and Rfxank

DIOPT Version :9

Sequence 1:NP_726059.5 Gene:CG42672 / 37433 FlyBaseID:FBgn0261554 Length:1642 Species:Drosophila melanogaster
Sequence 2:NP_035396.1 Gene:Rfxank / 19727 MGIID:1333865 Length:269 Species:Mus musculus


Alignment Length:291 Identity:81/291 - (27%)
Similarity:128/291 - (43%) Gaps:48/291 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   107 EETDAAVAAAEGKSSPAPN-QEHEEHSNQSPSRRFSHFNLALRRFSHIHAHNINRFGDSMGSLGH 170
            |.|..|......:..|.|: ::.|:..::||.   :...:.|..|. .....:|...|:..|...
Mouse     2 EPTQVAENLVPNQQPPVPDLEDPEDTRDESPE---NSDTVVLSLFP-CTPDAVNPEADASASSLQ 62

  Fly   171 RALLQY---IDN----NDISGLRAILDSRHLTIDDRDENATTVLMVVAGRGLTAFVREFLARGAD 228
            .:.|::   :.|    |::|.|.|.|||  |:|..           :|.:|..:.:::.|.:|| 
Mouse    63 GSFLKHSTTLTNRQRGNEVSALPATLDS--LSIHQ-----------LAAQGELSQLKDHLRKGA- 113

  Fly   229 VQAEDLDNWTALLCASRNGHLDVVQLLLDHGAEVEHRDMGGWTSLMWAAYRGHTELVRLLLDKGA 293
                    ..|..|.|.|.             .:...|..|:|.|:||:..|..|.||.|||.||
Mouse   114 --------CPACTCLSGNN-------------LINKPDERGFTPLIWASAFGEIETVRFLLDWGA 157

  Fly   294 DGNAHGNYHLGALLWAAGRGYKDIVELLVQRGAKVNVGDKYGTTALVWACRRGNVEIVDTLLKAG 358
            |.:........||..|:..||.|||.||:.|...:|:.|..|.|.|::|.|..:|:.|:.||..|
Mouse   158 DPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARG 222

  Fly   359 ANVDTAGMYSWTPLLVAAAGGHTDCVSSILE 389
            |::.|.....:||:.:|.|.|:.. |..::|
Mouse   223 ADLTTEADSGYTPMDLAVALGYRK-VQQVME 252

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42672NP_726059.5 ANK 169..289 CDD:238125 30/126 (24%)
Ank_2 173..266 CDD:289560 20/99 (20%)
ANK repeat 205..233 CDD:293786 5/27 (19%)
ANK 231..355 CDD:238125 40/123 (33%)
ANK repeat 235..266 CDD:293786 4/30 (13%)
Ank_2 240..332 CDD:289560 31/91 (34%)
ANK repeat 268..299 CDD:293786 15/30 (50%)
ANK repeat 301..332 CDD:293786 12/30 (40%)
Ank_2 306..398 CDD:289560 31/84 (37%)
ANK 329..454 CDD:238125 21/61 (34%)
ANK repeat 334..362 CDD:293786 11/27 (41%)
ANK repeat 367..398 CDD:293786 7/23 (30%)
ANK repeat 400..431 CDD:293786
Ank_4 401..454 CDD:290365
ANK 428..553 CDD:238125
ANK repeat 435..464 CDD:293786
Ank_2 438..530 CDD:289560
ANK repeat 466..497 CDD:293786
ANK repeat 499..530 CDD:293786
Ank_5 518..575 CDD:290568
KAP_NTPase 605..1136 CDD:284995
SAM_superfamily 1357..1392 CDD:188886
RfxankNP_035396.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36 8/36 (22%)
ANK 1 88..127 14/73 (19%)
Ank_2 93..161 CDD:289560 26/100 (26%)
ANK repeat 93..130 CDD:293786 10/69 (14%)
ANK 127..247 CDD:238125 46/120 (38%)
ANK repeat 132..163 CDD:293786 15/30 (50%)
ANK 2 132..161 15/28 (54%)
Ank_2 137..226 CDD:289560 37/88 (42%)
ANK repeat 165..196 CDD:293786 12/30 (40%)
ANK 3 165..194 11/28 (39%)
ANK 4 198..227 11/28 (39%)
ANK repeat 198..226 CDD:293786 11/27 (41%)
ANK 5 231..260 7/23 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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