DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9752 and RGD1311345

DIOPT Version :9

Sequence 1:	NP_611573.1	Gene:	CG9752 / 37431	FlyBaseID:	FBgn0034614	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001166907.1	Gene:	RGD1311345 / 361201	RGDID:	1311345	Length:	341	Species:	Rattus norvegicus

Alignment Length:	345	Identity:	151/345 - (43%)
Similarity:	225/345 - (65%)	Gaps:	17/345 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LSPRESGAYIVENAKHVRILPAGIEKLTQEIVKGLIEKRIAVENF-SQHELHPNPNQPEDYSKAA 69
            |.||||..::.||::.|.:...|:.::.:.::...:..|:  |.: :.|||:|..:.    ..|.
  Rat     7 LPPRESARFVAENSRDVGVDREGVRRVAELLLPAAVAWRL--EQWKALHELNPRGSD----EAAL 65

  Fly    70 DWVFVLDTLNFCFWTPNNYTKYKV----DGYTGYFALCAAIKRAIKEGVDVINPKFYSQIDLKTV 130
            ||||::|:|||.||......|.:|    ..||||:|||||:.||:.:|:.|.:..:|:.:.|..|
  Rat    66 DWVFMVDSLNFSFWAEREERKCEVRYGGTAYTGYWALCAAVNRALDQGIPVTSASYYATVTLDQV 130

  Fly   131 ENIFRSDDGETVIPLLQKRLESLHEVGKVLIDKYDGSFENVIKKAEKSAVRLLDLVVEEFPCFRD 195
            .||||||.. ..:|||::|...|:|.||:|::|:.|||.|.::|:.|||.:|:.|:||.||.:||
  Rat   131 RNIFRSDTA-VPMPLLEERHRILNETGKILLEKFGGSFLNCVQKSGKSAQKLMHLIVENFPSYRD 194

  Fly   196 EAEFAGKRVSILKRAQILVGDVWSCYRGQGLGFFNDIDQITMFADYRIPQVLVHFGSLEYTSELM 260
            ||.|.|||:|..|||||||.|.||...|:|.|.|.||..||||||||:||:|.|.|:|:|:.||:
  Rat   195 EAWFEGKRISFYKRAQILVADTWSVLEGKGDGSFEDISSITMFADYRLPQILAHLGALKYSDELL 259

  Fly   261 EFLKTDTILENGDPREVEIRGASIYIIEQVRDAVVKILKE--QHPEISLDNVNSIVIDQYLWDYR 323
            :.|....:|.|||.:||||||.||:.:|.:||.:|::|::  :.|.:   .||:|::|.:||||.
  Rat   260 KKLLEGEMLLNGDKQEVEIRGCSIWCVELIRDCLVELLEKRGESPPV---EVNAILLDYHLWDYA 321

  Fly   324 RRHNADLEHIPFHKVLSIYY 343
            |.|...::.:|||:...|||
  Rat   322 REHRDGMKGVPFHRTRCIYY 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9752	NP_611573.1	Q_salvage	55..340	CDD:287332	135/290 (47%)
RGD1311345	NP_001166907.1	Q_salvage	55..338	CDD:287332	135/290 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353426
Domainoid	1	1.000	277	1.000	Domainoid score	I1668
eggNOG	1	0.900	-	-		E1_KOG2524
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13005
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2670
OMA	1	1.010	-	-		QHG54407
OrthoDB	1	1.010	-	-		D1356655at2759
OrthoFinder	1	1.000	-	-		FOG0006019
OrthoInspector	1	1.000	-	-		oto95784
orthoMCL	1	0.900	-	-		OOG6_103850
Panther	1	1.100	-	-	LDO	PTHR21314
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4316
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770