Protein Alignment CG10505 and abcc6a

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_009300481.1
• Gene: abcc6a / 566555
• ZFINID: ZDB-GENE-050517-18
• Length: 1507
• Species: Danio rerio
• Alignment Length: 1334
• Identity: 460/1334 - (34%)
• Similarity: 700/1334 - (52%)
• Gaps: 121/1334 - (9%)

  Fly    15 PFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRNLQPHWEKESKK------ 73
            |...|:.:||.||.|...:..||.|..|.|..|:.......||.:..:|:..|..:..|
Zfish   205 PVQDASFLSKILFWWFSGLIFKGYRSPLQAEDLWSLREEDTSERIISDLEEEWTAKRTKLQQQEN 269

  Fly    74 ----------KNPSLMRLIFKVYGWQFVPVCILYSLLEMAIHSFQPLLLGG-------------- 114
                      :.|...:|:.|:...|....|:|.:|    ..||.|..|.|
Zfish   270 HMSTSAALGSRLPDQAQLLRKIQKEQSSGFCLLRTL----ARSFGPYFLTGTLCLIVHDVFMFSV 330

  Fly   115 ------LISYFAYGQTTVTKESAYLYAMGIVLCSLVTSLVFHPFMFYVFAVGTRVRLACAGLVYR 173
                  |:.:.....|.:.|  .|.||..:.|.|.:.|:..|.:.:..|.||.||:.|..|||||
Zfish   331 PQVLSLLLGFMKDEDTPLWK--GYFYATLMFLLSCLQSVFNHQYTYTCFTVGMRVKTAVMGLVYR 393

  Fly   174 KCLRASASSGEGLG-GQAISVMSIDLSQFDLTFYFFHDLWKGPVEACIFGYLMTRQVGWTSLIGI 237
            |.|..::|:..... |:.::::|.|..:......:|:.:|..|:|..:..:.:.:.:|.::|.||
Zfish   394 KSLVMNSSARRTCTVGEIVNLVSADTQKLMDFVVYFNAVWLAPIEVTLCLFFLWQHLGPSALAGI 458

  Fly   238 AFIVILIPLQAWAAKASASFGTRSAKHRDARVKLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSE 302
            |.::.:.||..:.|:..:.......|:.|.||||||||:..|:::|.|||||:|...:...|:.|
Zfish   459 ATVIFIFPLNGFIARKRSKLQEIQMKYMDGRVKLMNEILNGIKILKFYAWEKAFLEQVLGYREKE 523

  Fly   303 VKAIRGSMSIYA-ALQCTNMISKISLFLSLVAYVYVGD--LVTAKKVFILSSYYGLLNDSLLHYW 364
            :|.::.|..:|: :|...|..|.:..|.....||.:.|  ::.|:|:|:..:...:|...|...
Zfish   524 LKTLKKSQILYSVSLASFNSSSFLIAFAMFGVYVLIDDKNVLDAQKIFVSMALINILKTPLSQL- 587

  Fly   365 PMAITTWAQTLVSARRVVEFLLQVE-KPTEESCCRDNPGLELDAEKPKPAQSGRLHCVQSETKCL 428
            |.|::|..|.|||.:|:.:||.|.| ||       ||...|               ..:|:...:
Zfish   588 PFAMSTTMQALVSLKRLGKFLCQDELKP-------DNVARE---------------SFKSDVDGV 630

  Fly   429 SFRKVSASWDKPSIKQPRKPHIEGISFHINAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEV 493
            .|...:.||.|..     .|.::.||..:..|..|.:||:||||||:||.|:|||.|...|.|.|
Zfish   631 VFDNGTFSWSKDG-----PPCLKRISVKVPCGSLVAVVGHVGSGKSSLLSAMLGETEKRSGTVSV 690

  Fly   494 HGRISYAAQQPWVFQGSIRENILFVEQYEEKRYRAVVHACQLDRDLELLPRGDATVVGERGISLS 558
            .|.|:|..||.|:...|:::||||..:.:|..|:.|:.||.|..||:.||.||||.:||:|::||
Zfish   691 KGSIAYVPQQAWIQNASLQDNILFGREKKESWYQRVLEACALLPDLDNLPAGDATEIGEKGLNLS 755

  Fly   559 GGQKARIALARAVYRQADIYLFDDPLAAVDAQVGKLLMDKCF--HRLLDGKMRILVTHHVQLLKS 621
            ||||.|::|||||||:.|:||.||||:||||.||:.:.:|..  ..:|..|.|:||||.:..|..
Zfish   756 GGQKQRVSLARAVYRKGDVYLLDDPLSAVDAHVGQHIFNKVIGPKGILRDKTRVLVTHGMSFLPQ 820

  Fly   622 VDQLLLLEGGKLTQQGSYEEL-------KDVITHHAALDLEAIEADKQQVKR-----VLSQV--- 671
            .|.:|:|..|:::::|||:||       .|.|  |...:.|..|...:.::|     |...|
Zfish   821 ADLILVLVDGEISERGSYQELLNRNGAFADFI--HTFANSERKECFSEALQRGSRKSVRLSVTDY 883

  Fly   672 -----DRTSKQLSKGEEK----DPATIQDEN---------GNAEQQLQGAVSYDTYKAYFRALGA 718
                 |.:.:||..|:..    :|....||:         ...::...|.|..:.|..|||.:|.
Zfish   884 MPFSRDLSQEQLIGGDTNSIAIEPLPDSDEDHIPEDLGKLTKVDKARIGRVKLEMYIEYFRTIGL 948

  Fly   719 PFLVCLVLSMFVLARGCQAVMDIFISRWATWEEDRGYDSVDDYEATRTKMVIWYTVLLLLTLALF 783
            |.::.:|. ::...:......:.::|.||......|.....|     .|:.::..:.....:::|
Zfish   949 PLIISIVF-LYAFQQAASLSNNYWLSLWADQPVINGTQLNTD-----LKLGVYGALGFAQGISIF 1007

  Fly   784 LLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFFNANPSGRVLNRFSSDIQNVDVNLPQAMMDSL 848
             ..|......|:..|..||..|.:.::.:.|.||.:.|||.:||||:.:|..:|..:|..:...|
Zfish  1008 -GTTVAISLGCIIASRHLHLDLLNNVLHSPMSFFESTPSGNLLNRFAKEIDAIDNMIPDGLKMML 1071

  Fly   849 QFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFCRALYIGASRSLKRIESLTRSPIYSHTNQTFH 913
            .:...:..|.:||.:|..:..:....||.|..|.::.|:..|..|:|:||::|||||:|.|:|..
Zfish  1072 SYFFKLTEVCIIVLMATPFAAVIILPMVFLYGFIQSFYVATSCQLRRLESVSRSPIYTHLNETVQ 1136

  Fly   914 GHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVSANRAFSFWTDLICVIYILAVTFSFLVINQSF 978
            |.|.||:.:...:.....:...:.|.:|.|....|.|......:.:....:||.:...::...:.
Zfish  1137 GASVIRAFNEQSRFIMGANHKVDHNQTAYFPRFIATRWLGVNLEFLGNGIVLAASILSVMAKGTL 1201

  Fly   979 YSGDVGLAITQSMTLVIMCQWGMRQTAEMENNMTSVERVLEYAQTPSEPPLESPKSVNLAAEWPQ 1043
            ..|.||||::.|:.:.....|.:|...::|||:.|||||.|||.||.|... |.:..:|...|||
Zfish  1202 SPGMVGLAVSHSLQVTGFLSWIVRSWTDVENNIVSVERVKEYADTPKEAAW-SIEGSSLPPSWPQ 1265

  Fly  1044 AGHLRFQDLRMRYSPGDEDILRGLNFESQPMEKIGIVGRTGAGKSSIIQALFR-LALNEGTIEID 1107
            .|.:.|||..::|..|.|..|:|::......|||||||||||||||:...:|| |...:|.|.||
Zfish  1266 TGTIEFQDYGLQYRKGLELALKGISVHIHEREKIGIVGRTGAGKSSLALGIFRILEAAKGEIYID 1330

  Fly  1108 GLDIGKLGLHDLRSRISIIPQDPVLFSGTLRFNLDPFDEKSDESLWSALDDVKLKKHVASLEGGL 1172
            |::|.::|||||||||:|||||||||||:||.|||||:..|||.:|:||:...||..|:.|...|
Zfish  1331 GINIAEIGLHDLRSRITIIPQDPVLFSGSLRMNLDPFNAYSDEEVWNALELAHLKNFVSELPDKL 1395

  Fly  1173 SCRMQDGGSNFSMGQRQLVCLARAILRQNRVLVMDEATANVDTETDILIQETIQTKFAECTVLTI 1237
            :....:||.|.|:|||||||||||:||:.:|||:|||||.:|.|||.|||.||:::|.:|.||||
Zfish  1396 NHECSEGGENLSLGQRQLVCLARALLRKTKVLVLDEATAALDLETDTLIQSTIRSQFEDCAVLTI 1460

  Fly  1238 AHRLHTVMDNDSVLVMDAGQIVEFGAPHKLLQRK 1271
            ||||:|:||...|:|||.|.:||..:|..|:.::
Zfish  1461 AHRLNTIMDYTKVIVMDKGHVVEMDSPSNLIAKR 1494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	460/1332 (35%)
abcc6a	XP_009300481.1	MRP_assoc_pro	5..1506	CDD:188098	460/1334 (34%)