Protein Alignment CG10505 and l(2)03659

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_610482.3
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Alignment Length: 1332
• Identity: 532/1332 - (39%)
• Similarity: 828/1332 - (62%)
• Gaps: 70/1332 - (5%)

  Fly     4 SKQSSPKRE------SNPFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRN 62
            |:.:|.:.|      .||..::|.||...|.:...:||||.|:.||::.||..|....|:.|...
  Fly    73 SENNSAQNEKEKVLPENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNR 137

  Fly    63 LQPHWEKESKK--KNPSLMRLIFKVYGWQFVPVCILYSLLEMAIHSFQPLLLGGLISYFAYGQTT 125
            |...||:|.|.  ::|||:|.:.:|:|||.....:...::|:.:.:.||:.|..|||||: |:..
  Fly   138 LCASWERELKNDGRSPSLVRALLRVFGWQLGFPGLAIFVVELGLRTLQPIFLVKLISYFS-GEPD 201

  Fly   126 VTKESAYLYAMGIVLCSLVTSLVFHPFMFYVFAVGTRVRLACAGLVYRKCLRASASS-GEGLGGQ 189
            ......| ||:..::.|.:|.::..|..|.:..|..::|:|...:::||.||.:..: |:...|.
  Fly   202 AANAGFY-YAVAQIVISALTVMILTPTTFGIHHVCFKMRVAMGSMIFRKALRLTKGALGDTTSGH 265

  Fly   190 AISVMSIDLSQFDLTFYFFHDLWKGPVEACIFGYLMTRQVGWTSLIGIAFIVILIPLQAWAAKAS 254
            .::::|.|:.:.|...|..|.||.||::..:..|||.:::|.:::.|:.|:::.:|:|.:....:
  Fly   266 VVNLISNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRT 330

  Fly   255 ASFGTRSAKHRDARVKLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSEVKAIRGSMSI----YAA 315
            ::...::|:..|.|::::||||.||||:||||||:.|.:::...|:.|:..||....|    :|.
  Fly   331 SAIQLKAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFAR 395

  Fly   316 LQCTNMISKISLFLSLVAYVYVGDLVTAKKVFILSSYYGLLNDSLLHYWPMAITTWAQTLVSARR 380
               ..::|::::|||||.||.:|.:.|.:..|::::||.:|..::..|.|.||...||.|.|.||
  Fly   396 ---RIVLSRVAIFLSLVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRR 457

  Fly   381 VVEFLLQVEKPTEESCCRDNPGLELDAEKPKPAQSGRLHCVQSETKCLSFRKVSASWDKPSIKQP 445
            |.:|:...|..:.:.  .:.|..:.....| |:.:.....::|   .:|.|.:.|.||      |
  Fly   458 VEQFMQSEELGSSDK--SEGPSKDTVPGNP-PSNNNEADLLKS---AISIRDLKAKWD------P 510

  Fly   446 RKPH--IEGISFHINAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEVHGRISYAAQQPWVFQ 508
            ..|.  :.||:..|..|..|.::|..|||||:|:.|||||::...|:::|:|.:||.:|:.|:|.
  Fly   511 NSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFS 575

  Fly   509 GSIRENILFVEQYEEKRYRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYR 573
            |::|:||||.:..:.:||..||..|.|:||.:|||..|.|:|||||.:|||||||||:|||:|||
  Fly   576 GTVRQNILFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYR 640

  Fly   574 QADIYLFDDPLAAVDAQVGKLLMDKCFHRLLDGKMRILVTHHVQLLKSVDQLLLLEGGKLTQQGS 638
            :|.|||.||||:||||.|.:.|.|:|....|.|...:||||..|.|..|||:::|..|::...|.
  Fly   641 KASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGD 705

  Fly   639 YEEL--KDVITHHAAL---------DLEAIEADKQQVKRVLSQVDRTSKQL----SKGEEKDPAT 688
            ||.|  ..:||...:|         :.|.:..:....|..::.:...|:|.    |.|:|
  Fly   706 YESLLKTGLITGLGSLSKTDKAKTEEQEPLNLNSPDNKNEVTPIKENSEQTVGGSSSGKE----- 765

  Fly   689 IQDENGNAEQQLQGAVSYDTYKAYFRALGAPFLVCLVLSMFVLARGCQAVMDIFISRWATWEED- 752
                  :.|:|..|.:|...|:.||:|.|......::||..|||:......|.|::.|...|..
  Fly   766 ------HVERQESGGISLALYRKYFQAGGGLVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKESTA 824

  Fly   753 RGYDSVDDYEATRTKMVIWYTVLLLLTLALFLLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFF 817
            .|:..::|.| :::..|..||::::|::.:.|..:|..|.:..:.|:.||:.:::.:.||.|:||
  Fly   825 AGHGEMEDME-SKSMDVYKYTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFF 888

  Fly   818 NANPSGRVLNRFSSDIQNVDVNLPQAMMDSLQFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFC 882
            :.|..|.:||||:.|:..||..||..::|.:|..:.:..:::::|..|..||:|..::.::.|..
  Fly   889 SINKHGSILNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHL 953

  Fly   883 RALYIGASRSLKRIESLTRSPIYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVS 947
            |.||:..||.|||:|::.|||:|||...:.:|.:|||::||...||:.|..:|:.:|||.|:|:|
  Fly   954 RNLYLKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYIS 1018

  Fly   948 ANRAFSFWTDLICVIYILAVTFSFLVINQSFYSG---DVGLAITQSMTLVIMCQWGMRQTAEMEN 1009
            .::||.:..:.||||||..:|.||.    :|..|   ||||.|||:|.|:.|.|||:|||||:||
  Fly  1019 TSQAFGYCMNCICVIYISIITLSFF----AFPPGNGADVGLVITQAMGLIDMVQWGVRQTAELEN 1079

  Fly  1010 NMTSVERVLEYAQTPSEPPLESPKSVNLAAEWPQAGHLRFQDLRMRYSPG--DEDILRGLNFESQ 1072
            .||:||||:||.....|..||:|........||:.|.:.|::|.:||:|.  .|::|:.|:|..|
  Fly  1080 TMTAVERVVEYESIEPEGMLEAPDDKKPPKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQ 1144

  Fly  1073 PMEKIGIVGRTGAGKSSIIQALFRLALNEGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTL 1137
            |.||:||||||||||||:|.|||||:..:|::.||..|..::||||||.:||||||:|||||||:
  Fly  1145 PREKVGIVGRTGAGKSSLINALFRLSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTM 1209

  Fly  1138 RFNLDPFDEKSDESLWSALDDVKLKKHVASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNR 1202
            |:|||||||.|||.||..|::||||:.|:.|..||:.::.:||:|||:||||||||||||||:||
  Fly  1210 RYNLDPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENR 1274

  Fly  1203 VLVMDEATANVDTETDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHKL 1267
            :|||||||||||.:||.|||.||::||.:||||||||||||::|:|.|:|||||::||||:|::|
  Fly  1275 ILVMDEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYEL 1339

  Fly  1268 LQRKDGALL-KLVNQNDATTVKFLKRIASESY 1298
            :.:.|..:. .||||:...:.:.|.:||.|::
  Fly  1340 MTKSDSKVFHNLVNQSGRASYEGLLKIAQETF 1371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	519/1285 (40%)
l(2)03659	NP_610482.3	PLN03130	83..1369	CDD:215595	528/1318 (40%)