Protein Alignment CG10505 and rdog

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Alignment Length: 1382
• Identity: 704/1382 - (50%)
• Similarity: 946/1382 - (68%)
• Gaps: 109/1382 - (7%)

  Fly    11 RESNPFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRNLQPHWEKESKKKN 75
            |..|||.|||..|:|.|.||..:|::|.:..|...:||:|..:.|||.:|......||.|.|:.|
  Fly    10 RPKNPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWEDELKRSN 74

  Fly    76 PSLMRLIFKVYGWQFVPVCILYSLLEMAIHSFQPLLLGGLISYFAYGQTTVTKESAYLYAMGIVL 140
            ||::|:|.:.||..|||:.:.:|:.|....|..||.||||:.|||..||.:::.:|||||||||:
  Fly    75 PSVVRMILRAYGKIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDISENTAYLYAMGIVI 139

  Fly   141 CSLVTSLVFHPFMFYVFAVGTRVRLACAGLVYRKCLRAS-ASSGEGLGGQAISVMSIDLSQFDLT 204
            |.||..:.||||:||:|.|||::|||.:||:|||.|:.| :||.:||.|:||:::|.||.:||:.
  Fly   140 CMLVPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVSKSSSNDGLRGRAINILSNDLGRFDVA 204

  Fly   205 FYFFHDLWKGPVEACIFGYLMTRQVGWTSLIGIAFIVILIPLQAWAAKASASFGTRSAKHRDARV 269
            ..|.||.||||:|:.:.|:||.|::|.:::||::|::..|||||||||.:|.:...:|:..|.||
  Fly   205 LCFLHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWAAKKAAYYRQMTAERTDMRV 269

  Fly   270 KLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSEVKAIRGSMSIYAALQCTNMISKISLFLSLVAY 334
            |||||||..|||||||||||||.|:||.||..|||||||:..|:|||.||:|||.:|:||:|.:|
  Fly   270 KLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHAALGCTSMISPLSVFLALCSY 334

  Fly   335 VYVGDLVTAKKVFILSSYYGLLNDSLLHYWPMAITTWAQTLVSARRVVEFLLQVEKPTEESCCRD 399
            ||:||.:||:||:.:|||:.:||||::.:|||:||..|:.||||:|..:|||..:|       .:
  Fly   335 VYLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVSAKRCKDFLLDGDK-------AE 392

  Fly   400 NPGLELDA--------------EKPKPAQ-------SGRLH-------CVQSETKCLSFRKVSAS 436
            .| :.|:|              :|.|..:       :|::|       ..::..||:..:.||||
  Fly   393 VP-INLEANQQTGKNKRKISKKDKQKNVELNGSLLSNGQVHHNRLRDYDPEATKKCVVLKNVSAS 456

  Fly   437 WDKPSIKQPRKPH----IEGISFHINAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEVHGRI 497
            ||...      .|    ||..|..|.......:||.||:|||:.|:.:|||:.:.:|...|||:|
  Fly   457 WDTSD------GHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGEAMVHGKI 515

  Fly   498 SYAAQQPWVFQGSIRENILFVEQYEEKRYRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQK 562
            |||:|:.|||:|:||:||:|||.|.|:||:.||..|.|:||:|||||||.|||||||:|||||||
  Fly   516 SYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGVSLSGGQK 580

  Fly   563 ARIALARAVYRQADIYLFDDPLAAVDAQVGKLLMDKCFHRLLDGKMRILVTHHVQLLKSVDQLLL 627
            ||::|||||||:|||||.||||:|||..|||.:.|:|....|..|:||||||.||.|..|:.|||
  Fly   581 ARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCIRDFLSNKIRILVTHQVQYLFDVEHLLL 645

  Fly   628 LEGGKLTQQGSYEELK----------------DVITHHAALDLEAIEADKQQVKRVLSQVDRTSK 676
            :..||:..||||:||:                .:.||..:..|...:::|        .::....
  Fly   646 MGSGKIMAQGSYQELQRSRQFQFLEQTQHDESGIDTHSVSSYLSRSDSEK--------SMEHQHN 702

  Fly   677 QLSKGEEKDPATIQDENGNAEQQLQGAVSYDTYKAYFRALGAPFLVCLVLSMFVLARGCQAVMDI 741
            ||.:.:|      ..|:.|.|||..|::....|.:|.:||.:.||:.:|:|:||.||.....:|.
  Fly   703 QLLRPDE------HVEDVNQEQQTVGSIKMHVYASYIKALDSTFLLGIVISLFVCARIMLTGVDY 761

  Fly   742 FISRWATWEEDRG---------------------YDSVDDYEA----------TRTKMVIWYTVL 775
            |:|||..|||...                     .::.|.|.|          .|.::|::|..:
  Fly   762 FLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQELVLFYATI 826

  Fly   776 LLLTLALFLLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFFNANPSGRVLNRFSSDIQNVDVNL 840
            |..||.::|:||||||.|||||||.|||:|:.||.||.|||||.|.|||:|||||.||:.||.:|
  Fly   827 LGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIRTVDTDL 891

  Fly   841 PQAMMDSLQFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFCRALYIGASRSLKRIESLTRSPIY 905
            |..::|.|.|::||..|::|||||||||||||||:.::|...|.||:..|||:||:||::|||::
  Fly   892 PHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLESISRSPVF 956

  Fly   906 SHTNQTFHGHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVSANRAFSFWTDLICVIYILAVTFS 970
            |.|||||.|.:|||::.|...|||.||.:||||:||.||::|..|||:.|:|::|::|:.|||||
  Fly   957 SLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDVLCIVYMTAVTFS 1021

  Fly   971 FLVINQSFYSGDVGLAITQSMTLVIMCQWGMRQTAEMENNMTSVERVLEYAQTPSEPPLESPKSV 1035
            ||::...|.||||||||..|.|:..|||||||||||:||.||||||||||.:.|||..||:|:..
  Fly  1022 FLLLKDEFDSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEYTEQPSEALLETPEKF 1086

  Fly  1036 NLAAEWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPMEKIGIVGRTGAGKSSIIQALFRLALN 1100
            ...:|||..|.:.|.:.::||||.:..:|:.|||..:|.||||||||||||||||||::||||.|
  Fly  1087 KPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSIFRLACN 1151

  Fly  1101 EGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTLRFNLDPFDEKSDESLWSALDDVKLKKHV 1165
            ||.|.||.:||..:|||||||::|||||||||||||||:||||.||:|||.:|.||.||:|:.:|
  Fly  1152 EGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEMWKALGDVELRSYV 1216

  Fly  1166 ASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNRVLVMDEATANVDTETDILIQETIQTKFA 1230
            ::|.|||:|||.|||||||:||||||||||||||.|::|:|||||||||.|||.|||:||::|||
  Fly  1217 STLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKLIQQTIRSKFA 1281

  Fly  1231 ECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHKLLQRKDGALLKLVNQNDATTVKFLKRIAS 1295
            .|||||||||||||||:|.|||||||::.|.|.|::||||..|.|.:||:...|.|...|::.|.
  Fly  1282 HCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQRTGGYLRQLVDNTGAATSFALQQAAE 1346

  Fly  1296 ESYMRRNRRDSLTISEE 1312
            :||.::...|. |.:|:
  Fly  1347 QSYSKQILGDD-TAAED 1362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	688/1335 (52%)
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	689/1336 (52%)