| Sequence 1: | NP_611571.2 | Gene: | CG10505 / 37428 | FlyBaseID: | FBgn0034612 | Length: | 1312 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_504463.1 | Gene: | cft-1 / 178939 | WormBaseID: | WBGene00000477 | Length: | 1247 | Species: | Caenorhabditis elegans |
| Alignment Length: | 1314 | Identity: | 296/1314 - (22%) |
|---|---|---|---|
| Similarity: | 581/1314 - (44%) | Gaps: | 138/1314 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 14 NPFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRNLQP--HWEKESKKKNP 76
Fly 77 SLMRLIFKVY--GWQFVPVCILYSLLEMAIHSFQPLLLGGLISYFAYGQTTVTKESAYLYAMGIV 139
Fly 140 LCSLVTSLVFHPFMFYVFAVGTRVRLACAGLVYRKCLRASASSGEGLGGQAISVMSIDLSQFDLT 204
Fly 205 FYFFHDLWKGPVEACIFGYLMTRQVGWTSLIGIAFIVILI-----PLQAWAAKASASFGTRSAKH 264
Fly 265 RDARVKLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSEVKAIRGSMSIYAALQCTNMISK-ISLF 328
Fly 329 LSLVAY--VYVGDLVTAKKVFILSSYYGLLNDSLLHYWPMAITTWAQTLVSARRVVEFLLQVEKP 391
Fly 392 TEESCCRDNPGLELDAEKPKPAQSGRLHCVQSETKCLSFRKVSASWDKPSIKQPRKPHIEGISFH 456
Fly 457 INAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEVHGRISYAAQQPWVFQGSIRENILFVEQY 521
Fly 522 EEKRYRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYRQADIYLFDDPLAA 586
Fly 587 VDAQVGKLLMDKCFHRLL--DGKMR----ILVTHHVQLLKSVDQLLLLEGGKLTQQGSYE----- 640
Fly 641 -ELKDVITHHAALD--LEAIEADKQQVKRVLSQVDRTSKQLSKGEEKDPATIQDENGNAEQQLQG 702
Fly 703 AVSYDTYKAYFRA---LGAPFLVCLVLSMFVLARGCQAVMDIFISRW--ATWEEDRGYDSVDDYE 762
Fly 763 ATRTKMVIWYTVLLLLTLALFLLRTFGFFFMC-LRISLTLHDQLYHGIIRAWMYFFNANPSGRVL 826
Fly 827 NRFSSDIQNVDVNLPQAMMDSLQFLVDVVAVLVIVAI-ANYWLLIPAAIMVILL----YFCRALY 886
Fly 887 IGASRSLKRIESLTRSPIYSHTNQTFHGHSTIRSMDAMPQ-LEQTFHGHQNTNSSAL----FLYV 946
Fly 947 SANRAFSFWTDLICVIYILAVTFSFLVINQSFYSGDVGLAITQSMTLVI--MCQWGMRQTAEMEN 1009
Fly 1010 NMTSVERVLEYAQTPSEPPLESPKSVNLAAEWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPM 1074
Fly 1075 EKIGIVGRTGAGKSSIIQALFRL--ALNEGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTL 1137
Fly 1138 RFNLDPFDEKSDESLWSALDDVKLKKHVASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNR 1202
Fly 1203 VLVMDEATANVDTETDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHKL 1267
Fly 1268 LQRKDGALLK-LVN 1280 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG10505 | NP_611571.2 | CFTR_protein | 12..1268 | CDD:273530 | 290/1299 (22%) |
| ABC_membrane | 95..360 | CDD:294371 | 47/272 (17%) | ||
| ABCC_MRP_domain1 | 428..632 | CDD:213217 | 68/209 (33%) | ||
| ABC_membrane | 728..994 | CDD:294371 | 51/278 (18%) | ||
| ABCC_MRP_domain2 | 1045..1264 | CDD:213211 | 64/220 (29%) | ||
| cft-1 | NP_504463.1 | MdlB | 76..631 | CDD:224055 | 136/591 (23%) |
| ABC_membrane | 93..359 | CDD:294371 | 47/273 (17%) | ||
| P-loop_NTPase | 407..607 | CDD:304359 | 68/209 (33%) | ||
| ABC_membrane | 696..938 | CDD:294371 | 49/262 (19%) | ||
| P-loop_NTPase | 1010..1228 | CDD:304359 | 64/220 (29%) | ||
| EcfA2 | 1012..1234 | CDD:224047 | 65/225 (29%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C160157423 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0054 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D138195at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24223 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.850 | |||||