Protein Alignment CG10505 and LOC1277540

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_061510128.1
• Gene: LOC1277540 / 1277540
• VectorBaseID: AGAMI1_011554
• Length: 1414
• Species: Anopheles gambiae
• Alignment Length: 1358
• Identity: 367/1358 - (27%)
• Similarity: 606/1358 - (44%)
• Gaps: 211/1358 - (15%)

  Fly     2 DASKQSSPKRESNPFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRNLQPH 66
            |:|..|:..|      |.|.|....|.||.|.:|:..|..:          :|...:|.:...|.
Mosquito   156 DSSTGSNTPR------KPNFIRGLFFSWMDSTYREAHRGSV----------AFYQGTLFQGTLPE 204

  Fly    67 ----------WEK-----------------ESKKKNPSLMRLIFKVYGW-------QFVPVCILY 97
                      :||                 ||::...::.:|:....|.       :||.:.:.:
Mosquito   205 DRRCEQLLELYEKANARRGYTAVDDGSGRMESERCRFTIGKLLSPFRGEIILAGLNRFVLISLFF 269

  Fly    98 ---SLLEMAIHSFQPLLLGGLISYFAYGQTTVTKESAYLYAMGIVLCSLVTSLVFHPFMFYVFAV 159
               .||.:.:...||.:         |.:..||.    |:....|:..|.|.     :......:
Mosquito   270 LCPYLLRLLLEESQPRM---------YQKWIVTA----LFDASTVIAILNTH-----YQHTTQDI 316

  Fly   160 GTRVRLACAGLVYRKCLRASASSGEGLGGQAIS-VMSIDLSQFDLTFYFFHDLWKGPVEACI-FG 222
            |.|:|....|.:||..|.      :|:...|.| .::.|.:.|.......|.:|..|:...| |.
Mosquito   317 GLRIRSILMGAIYRSILH------DGITSNASSDTLTSDTALFVPFIQNLHMMWSAPLIILITFV 375

  Fly   223 YLMTRQVGWTSLIGIAFIVILIPLQAWAAKASASFGTRSAKHRDARVKLMNEIIGAIQVIKMYAW 287
            .|....:|....:|:|.||.:|.:....||..|:.......|.:.||:|....|..:|.||....
Mosquito   376 ALWVGVLGPIGTVGLAIIVAVIAITRKLAKKIAAQEKHITAHSNDRVRLTTASIEQMQQIKSDLM 440

  Fly   288 EKSFGRLIAAVRQSEVKAIRGSMSIYAALQ-----CTNMISKISLFLSLVAYVYV---GDLVTAK 344
            |..|.:.|...|::|:..: .:..:|.||:     .|.||.....||    ::||   |.|:|.:
Mosquito   441 EPFFEQRIGEHRRAELSHM-CTYILYDALKYLLSIATPMIVACGTFL----FMYVVGSGALLTVQ 500

  Fly   345 KVFILSSYYGLLNDSLLHYWPMAITTWAQTLVSARRVVEFLLQVEKPTEESCCRDNPGLELDAEK 409
            .:|:..:.:||....|... |..:..|. |:....:|:..::...|.|:.|......|.....
Mosquito   501 SMFVAIALFGLTRYPLSEL-PNLMANWG-TINVKLQVINEVVCSGKQTKSSGKMPQNGTATGG-- 561

  Fly   410 PKPAQSGRLHCVQ-----------------SETKCLSFRKVSASWDKPSIKQPRKPHIEGISFHI 457
               |..|....:|                 |..:.|...:...|.:|.:|       :.||:..:
Mosquito   562 ---AGRGSFEKMQEVVHTFVDQLEDSIADTSRAEVLRIERAKFSTEKNTI-------LRGINLTL 616

  Fly   458 NAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEV-HGRISYAAQQPWVFQGSIRENILFVEQY 521
            ..|.|.|:.|..||||::||.|::|.::...|...: ..|::|..|.||:..|:||.||||.::|
Mosquito   617 REGTFTGVSGTHGSGKTSLLRAMIGRLQRTGGTSTIAWNRVAYCPQTPWIHSGTIRSNILFGQEY 681

  Fly   522 EEKRYRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYRQADIYLFDDPLAA 586
            |:.||..|:.||.|:.||:..|..|..||.|.|.||||||..|::|||||||.||:||.||||.:
Mosquito   682 EKSRYEEVLRACCLEEDLKTFPDYDERVVSEGGHSLSGGQARRVSLARAVYRHADVYLLDDPLRS 746

  Fly   587 VDAQVGKLLMDKCFHR---LLDGKMRILVTHHVQLLKSVDQLLLLEGGKLTQQGSYEELKDV-IT 647
            :|..|.:.:.:..|||   ||.|...:.::|..:.|...|::|::.||.:.     :.||.. ::
Mosquito   747 LDPNVARKVFEGVFHRQHGLLAGCTCVFISHDPEHLSIADKVLVMAGGTIE-----KVLKPAEVS 806

  Fly   648 HHAALDLEAIEADKQQVKRVLSQVDRTSKQLSKGEEKDPATIQDENGNAEQQLQGAVSYDTYKAY 712
            ......|...|.:.:|.::|.....:..|:..|.:.|.     .::|      :|.||...|..:
Mosquito   807 VELLCQLNGAEDEPEQEEKVPKADQQNKKRARKAQPKG-----TDHG------EGNVSLGLYVTF 860

  Fly   713 FRALGAPFLV---CLVLSMFVLARGCQAVMDIFISRWATWEEDRGYDSVDDYEATRTKMVIWYTV 774
            .|.|...:.|   |...::..|    ..|:...:::||.             .|.:|...:.:|.
Mosquito   861 ARMLKRRYCVGALCFESAVTAL----DIVIITLLAQWAA-------------SAKQTSGALLHTT 908

  Fly   775 -LLLLTLALFLLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFFNANPSGRVLNRFSSDIQNVDV 838
             :|.:.:.|..|:|....:..|.:|..:|.|:...|:|..|.||:.|.||.::||||:|::.||.
Mosquito   909 WILCVWVLLIFLKTAIIHWAGLSLSKRVHSQMLATILRQPMEFFDLNDSGVIVNRFSNDLKVVDK 973

  Fly   839 NLPQAMMD--SLQFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFC---RAL--YIGASRSLKRI 896
            .:..::..  |..|.|....:|.:..:.:..||...|....|:..|   |.|  ::..:|:|||.
Mosquito   974 TIITSVRSVLSASFSVLGTLMLFVYKLHSKLLLFVLAFTAALMLVCGLKRLLSYHLQVARTLKRF 1038

  Fly   897 ESLTRSPIYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVSANRAFSFWTDL--- 958
            |:.:||||....|:|..|..||::.:|..:|.:.|....:|:.:    |:..||..:.|..:
Mosquito  1039 EASSRSPIILQYNETIQGIDTIKAYEAEDRLLRQFFERVDTHQN----YIYHNRFANRWIGIRLE 1099

  Fly   959 ----ICVIYILAVTFSFLVINQSFYS-GDVGLAITQSMTLVIMCQWGMRQTAEMENNMTSVERVL 1018
                |.:.|:..:|.|    |||... ..||:.::..:.|:......:.....:|.|:.|.|||.
Mosquito  1100 FIGAIVIYYVALLTVS----NQSMVGFAFVGIIVSYVLRLIPSLNSLLLALGALEENIISFERVA 1160

  Fly  1019 EY----AQTPSEPPLESPKSVNLAAEWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPMEKIGI 1079
            :|    .:|..|..::.|.|.  ..:.|..|.:.::|..:.::.| ..:|..:.......||:||
Mosquito  1161 QYLDLQRETNDETGVDYPTSG--MDKHPVLGPIIYRDFSLTHADG-STVLHNVTLTIAAGEKLGI 1222

  Fly  1080 VGRTGAGKSSIIQALFRL--ALNEGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTLRFNLD 1142
            |||||:||||.|..|||.  ....|.|.|..:::|::.|..||..::::||...||||.::..:|
Mosquito  1223 VGRTGSGKSSFIGTLFRFYPKHTTGYISIAHVELGRISLKKLRGELTLVPQSTSLFSGVVQNFID 1287

  Fly  1143 PFDEKSDESLWSALDDVKL-KKHVAS-LEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNRVLV 1205
            |.:..:||.|...|.:..| ..|:|: ||            |.|:||.||:||.|..||:..:::
Mosquito  1288 PRNGHTDEELIRCLRECGLGNVHLATPLE------------NLSVGQCQLLCLVRGFLRKKPIII 1340

  Fly  1206 MDEATANVDTETDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGA 1263
            :||||:.:|..|:.||.:.:..:|...|||.|||.|:|:.:...||.:..|::.:..|
Mosquito  1341 LDEATSALDEATEDLILKVLDKQFHGRTVLMIAHHLNTLRNCHRVLWLQEGRVRKIAA 1398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	363/1345 (27%)
LOC1277540	XP_061510128.1	None