Protein Alignment CG10505 and Abcc5

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_446376.2
• Gene: Abcc5 / 116721
• RGDID: 70913
• Length: 1436
• Species: Rattus norvegicus
• Alignment Length: 1364
• Identity: 432/1364 - (31%)
• Similarity: 720/1364 - (52%)
• Gaps: 151/1364 - (11%)

  Fly    11 RESNPFIKANIISKWLFLWM----HSVFRKGR--REELDASKLYEHLPSFDSESLTRNLQPHWEK 69
            :..:|...|.:.|...|.|:    ..|.:||.  .|::.....||     .|:...|.|:..|::
  Rat    96 KHQHPVDNAGLFSYMTFSWLSPLAQVVHKKGELLMEDVWPLSKYE-----SSDVNCRRLERLWQE 155

  Fly    70 ESKKKNP---SLMRLIFKVYGWQFVPVCILYSLL-----EMAIHSFQPLLLGGLISYFAYGQTTV 126
            |..:..|   ||.|::     |.|....::.|::     ::|..|....::..|:.|      |.
  Rat   156 ELNEVGPDAASLRRVV-----WIFCRTRLILSIVCLMITQLAGFSGPAFVVKHLLEY------TQ 209

  Fly   127 TKESAYLYAMGIVLCSLVTSLVFHPFMFYVFAV----GTRVRLACAGLVYRKCLRASASSGEGLG 187
            ..||...|::.:||..|:|.:|....:...:|:    |.|:|.|...:.::|.|:......:.|
  Rat   210 ATESNLQYSLLLVLGLLLTEVVRSWSLALTWALNYRTGVRLRGAVLTMAFKKILKLKNIKEKSL- 273

  Fly   188 GQAISVMSIDLSQFDLTFYFFHDLWKGPVEA---CIFGYLMTRQVGWTSLIGIAFIVILIPLQAW 249
            |:.|::.|.|..:..........|..|||.|   .|:..::   :|.|..:|.|..::..|...:
  Rat   274 GELINICSNDGQRMFEAAAVGSLLAGGPVVAILGMIYNVII---LGPTGFLGSAVFILFYPAMMF 335

  Fly   250 AAKASASFGTRSAKHRDARVKLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSEVKAIRGS---MS 311
            .::.:|.|..:.....|.||:.|||::..|:.||||||.|:|.:.:..:|:.|.:.:..:   .|
  Rat   336 VSRLTAYFRRKCVAATDDRVQKMNEVLTYIKFIKMYAWVKAFSQCVQKIREEERRILEKAGYFQS 400

  Fly   312 IYAALQCTNMISKISLFLSLVAYVYVGDLVTAKKVFILSSYYGLLNDSLLHYWPMAITTWAQTLV 376
            |...:  ..::..|:..::...::.:|..:||.:.|.:.:.:..:..: |...|.::.:.::..|
  Rat   401 ITVGV--APIVVVIASVVTFSVHMTLGFDLTAAQAFTVVTVFNSMTFA-LKVTPFSVKSLSEASV 462

  Fly   377 SARRVVEFLLQVE------KP-----------------TEESCCRDNPGLELDAEKPKPAQSGRL 418
            :..|.....|..|      ||                 :..|..:.:|.|....:|.|.|..|:
  Rat   463 AVDRFKSLFLMEEVHMIKNKPASPHIKIEMKNATLAWDSSHSSTQSSPKLTPKVKKDKRAPKGK- 526

  Fly   419 HCVQSETKCLSFRKVSA------------SWDKPSIKQPRKPHIE-----------GISFHINAG 460
               :.:::.|...:..|            |.::||.::.....|.           .|...|..|
  Rat   527 ---KEKSRQLQHTEHQAVLAEQKGHLLLDSDERPSPEEEEGKQIHAGSMRLQRTLYNIDLEIEEG 588

  Fly   461 QFVGIVGNVGSGKSTLLHAILGEIELMQGRVEVHGRISYAAQQPWVFQGSIRENILFVEQYEEKR 525
            :.|||.|:|||||::|:.||||::.|::|.:.|.|..:|.|||.|:...::|:||||.::::|:|
  Rat   589 KLVGICGSVGSGKTSLISAILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKEFDEER 653

  Fly   526 YRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYRQADIYLFDDPLAAVDAQ 590
            |.:|:::|.|..||.:||..|.|.:||||.:|||||:.||:||||:|....||:.||||:|:||.
  Rat   654 YNSVLNSCCLRPDLAILPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAH 718

  Fly   591 VGKLLMDKCFHRLLDGKMRILVTHHVQLLKSVDQLLLLEGGKLTQQGSYEELKDVITHHAALDLE 655
            ||..:.:....:.|..|..:.|||.:|.|...|:::.::.|.:|::|::|||.::...:|.:...
  Rat   719 VGNHIFNSAIRKRLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNN 783

  Fly   656 AIEADKQQVKRVLSQVDRTSKQLSKGEEKDPATIQDENG---------NAEQQLQGAVSYDTYKA 711
            .:..:...|: :.|:.:.:..|.|:.:...|.:::.|..         ..|::.||:|.:..|..
  Rat   784 LLLGETPPVE-INSKKEASGSQKSQDKGPKPGSVKKEKAVKSEEGQLVQVEEKGQGSVPWSVYWV 847

  Fly   712 YFRALGAPFLVCLVLSMFVLARGCQAVMDIFISRWATWEEDRGYDSVDDYEATRTKM-------- 768
            |.:|.|.|....:::.:|:|..|..|....::|.|.  ::..|..:|  :|..|:.:
  Rat   848 YIQAAGGPLAFLVIMVLFMLNVGSTAFSTWWLSYWI--KQGSGNSTV--FEGNRSSVSDSMRDNP 908

  Fly   769 -VIWYTVLLLLTLALFL----LRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFFNANPSGRVLNR 828
             :.:|..:..|::|:.|    :|...|....||.|..|||:|:..|:|:.|.||:..|:||:|||
  Rat   909 FLQYYASIYALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNR 973

  Fly   829 FSSDIQNVDVNLP-QAMMDSLQFLVDVVAVLVIVA-IANY--WLLI---PAAIMVILLYFCRALY 886
            ||.|:..|||.|| ||.|    |:.:|:.|...|. ||..  |.|:   |..|:..:|:....:.
  Rat   974 FSKDMDEVDVRLPFQAEM----FIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSVLHIVSRVL 1034

  Fly   887 IGASRSLKRIESLTRSPIYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQ---NTNSSALFLYVSA 948
            |   |.|||::::|:||..||...:..|.:||.   |..:.::..|.:|   :.|.:..||:..|
  Rat  1035 I---RELKRLDNITQSPFLSHITSSIQGLATIH---AYNKRQEFLHRYQELLDDNQAPFFLFTCA 1093

  Fly   949 NRAFSFWTDLICVIYILAVTFSFLVINQSFYSGDVGLAITQSMTLVIMCQWGMRQTAEMENNMTS 1013
            .|..:...|||.:..|.......::::....|...||||:.::.|..:.|:.:|..:|.|...||
  Rat  1094 MRWLAVRLDLISIALITTTGLMIVLMHGQIPSAYAGLAISYAVQLTGLFQFTVRLASETEARFTS 1158

  Fly  1014 VERVLEYAQTPSEPPLESPKSVNLAA---EWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPME 1075
            |||:..|.:|.|   ||:|..:...|   :|||.|.:.|::..|||......:|:.::|..:|.|
  Rat  1159 VERINHYIKTLS---LEAPARIKNKAPPHDWPQEGEITFENAEMRYRENLPLVLKKVSFTIKPKE 1220

  Fly  1076 KIGIVGRTGAGKSSIIQALFRLA-LNEGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTLRF 1139
            |||||||||:||||:..|||||. |:.|.|:|||:.|..:||.||||:::||||:|||||||:|.
  Rat  1221 KIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRISDIGLADLRSKLAIIPQEPVLFSGTVRS 1285

  Fly  1140 NLDPFDEKSDESLWSALDDVKLKKHVASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNRVL 1204
            |||||::.::|.:|.||:...:|:.:|.|...|...:.:.|.|||:|:|||:|:|||:||..::|
  Rat  1286 NLDPFNQYTEEQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKIL 1350

  Fly  1205 VMDEATANVDTETDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHKLL 1268
            ::|||||.:|||||:||||||:..||:||:||||||||||:.:|.::|:..||:|||..|..||
  Rat  1351 ILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLL 1414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	432/1360 (32%)
Abcc5	NP_446376.2	PLN03130	100..1424	CDD:215595	432/1360 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	499..569		13/73 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	795..822		5/26 (19%)