Protein Alignment CG10505 and abcc8

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_031756190.1
• Gene: abcc8 / 101730668
• -ID: -
• Length: 1580
• Species: Xenopus tropicalis
• Alignment Length: 1418
• Identity: 403/1418 - (28%)
• Similarity: 682/1418 - (48%)
• Gaps: 234/1418 - (16%)

  Fly    15 PFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRN--LQPHWEKESKKKNP- 76
            ||:  |::||..:.||::..:...::.:|. |....|| ....::|..  |...:..:..|.:|
 Frog   220 PFV--NLLSKGTYWWMNTFIKTAHKKPIDL-KAIGKLP-IAMRAVTNYLLLNKAFHSQKSKSSPC 280

  Fly    77 ----------------------SLMRLIFKVYGWQFVPVCI--LYSLLEMAIHSF--QPLLLGGL 115
                                  |:.|::..:.|:. .|:||  :...|.....:|  ||:.||
 Frog   281 PAGPKSIWFALCQAFGRPLILSSIFRIMADMLGFA-GPLCISGIVHHLSQENKTFHPQPIFLG-- 342

  Fly   116 ISYFAYGQTTVTKESAYLYAMGIVLCSLVTSLVFHPFMFYV-FAVGTRVRLACAGLVYRKCLRAS 179
             .:|...|..:.  :||:.|: ::..:|:....|....:|| ...|..:|.|....:|.|.:..|
 Frog   343 -VFFISSQEFLA--NAYVLAV-LLFFALLLQRSFLQASYYVAIETGINLRGAIQTKIYNKIMHLS 403

  Fly   180 ASS---GEGLGGQAISVMSIDLSQFDLTFYFFHDLWKGPVEACIFGYLMTRQVGWTSLIGIAFIV 241
            .|:   ||...||..::::||.:|....|:...:||..||:..:...|:...:|.::|||...|:
 Frog   404 TSNMSMGEMSSGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGISALIGAVVII 468

  Fly   242 ILIPLQAWAAKASASFGTRSAKHRDARVKLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSEVKAI 306
            :|.|:|.:.|...:.....:.::.:.|:|..||::..|:::|:|:||..|...:...||.|:.::
 Frog   469 VLAPIQYFVATKLSQAQRSTLEYSNERLKKTNEMLRGIKLLKLYSWEHIFHSSVEETRQKEMNSL 533

  Fly   307 RG-----SMSIY-------AALQCTNMI----------------SKISLFLSLVAYVYVGDLVTA 343
            :.     |:||:       ||:..|.::                :.:|||..||.
 Frog   534 KAFALYTSISIFMNAAIPIAAVLITFVVHVHLLHREQFSPAVAFASLSLFHILVT---------- 588

  Fly   344 KKVFILSSYYGLLNDSLLHYWPMAITTWAQTLVSARRVVEFLL------QVEK--PTEESCCRDN 400
             .:|:|||               .:.:..:.|||.:::.||..      :|||  |:.:|..::.
 Frog   589 -PLFLLSS---------------VVRSTVKALVSVQKLSEFFSSEEIGEEVEKCPPSNKSVPQNK 637

  Fly   401 ----PGLELDAEKP--------KPAQSGRLHCVQSETKCLSFRKVSASW--DKPSIKQPRKPHIE 451
                |...::.::|        ...|.|..:..:....|:.......:|  |.|       |.:.
 Frog   638 YQAVPLKVVNRKRPIRDDWNHFNSRQRGAPNPTEGNEFCIKVTSGFFTWTPDGP-------PALS 695

  Fly   452 GISFHINAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEVH---------------------- 494
            .|...|..||...|||.||.|||:||.|.|||:..:.|.|..:
 Frog   696 SIDIRIPQGQLTMIVGQVGCGKSSLLLATLGEMHKISGDVSWNSTVPDSETGEDVNPDKETAIDV 760

  Fly   495 -----GRISYAAQQPWVFQGSIRENILFVEQYEEKRYRAVVHACQLDRDLELLPRGDATVVGERG 554
                 |.::||:|:||:...::.|||.|...:.:::|:|::.||.|..|:::||.||.|.:||||
 Frog   761 ETRRRGAVAYASQKPWLLNATVEENITFESPFNKQKYKAIIDACSLQPDIDILPHGDQTQIGERG 825

  Fly   555 ISLSGGQKARIALARAVYRQADIYLFDDPLAAVDAQVGKLLMDKCFHRLLDGKMR--ILVTHHVQ 617
            |:|||||:.||::||.:|:|..:...|||.:|:|..:...||.:...::|....|  :||||.:|
 Frog   826 INLSGGQRQRISVARVLYQQTSVVFLDDPFSALDIHLSDHLMHEGILKMLRDNKRTTVLVTHKLQ 890

  Fly   618 LLKSVDQLLLLEGGKLTQQGS-----------YEELKDVITHH-AALDLEAIEADKQQVKR---- 666
            .|...|.::.::.|.:.::|:           ||..|.::... ..|:.|.|...|...:|
 Frog   891 YLPHADWIIAMKDGTIQREGTLKDIQKSDPELYEHWKTLMNRQDQELEKEIILDRKAGGERMNLT 955

  Fly   667 --------VLSQVDRTSKQLSKGEEKDPATIQDENGNAEQQLQGAVSYDTYKAYFRALGAPFLVC 723
                    :|...:...:::|:.||      .|:|.::....:..:.:.....|..:.|...|..
 Frog   956 RTIYPRDALLGDDEEDEEEISESEE------DDDNLSSVLHQRAKMPWRACGKYLSSAGILLLPL 1014

  Fly   724 LVLSMFVLARGCQAVMDIFISRWATWEEDRGYDSVDDYEATRTKMVI------------------ 770
            ||||. :|.......:|.::::|.:              |..|.:.:
 Frog  1015 LVLSQ-LLKHSVMVAIDFWLAKWTS--------------AAITNLSVANCSGRPTCRFDHSPYSM 1064

  Fly   771 WYTVLLLLTLALFLLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFFNANPSGRVLNRFSSDIQN 835
            .:::|..:.:.:.|..:....:..||::..||..|.:.||.|.|.||...|.|.:|||||:|...
 Frog  1065 AFSILSCVGIIMCLATSIAVEWTGLRVAKKLHSSLLNAIILAPMRFFETTPLGSILNRFSADFNT 1129

  Fly   836 VDVNLPQAMMDSLQFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFCRALYIGASRSLKRIESLT 900
            :|.::|..:....:..:..|:.|.:::......||....:.|:.||.:..:..|||.|:::|..|
 Frog  1130 IDQHIPATLECLSRSTLLCVSALAVISYVTPVFLISLVPLAIICYFIQKYFRVASRDLQQLEDST 1194

  Fly   901 RSPIYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVSANRAFSFWTDL------I 959
            :.|:.||..:|..|.:|||:....|:..|....|.::|:.|.....:|||    |.::      .
 Frog  1195 QLPLLSHFAETVEGLTTIRAFRYEPRFRQKLLEHTDSNNIASLFLTAANR----WLEVRMEYIGA 1255

  Fly   960 CVIYILAVTFSFLVINQSFYSGDVGLAITQSMTLVIMCQWGMRQTAEMENNMTSVERVLEYAQTP 1024
            ||:.|.||......::.:..||.|||.:|.::.:.....|.:|..::||..:.:|:|:....:|.
 Frog  1256 CVVLIAAVASITNSLHYNLSSGLVGLGLTYALMVSNYLNWMVRNLSDMEIQLGAVKRINGLLKTE 1320

  Fly  1025 SE--PPLESPKSVNLAAEWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPMEKIGIVGRTGAGK 1087
            .|  ..|.||  ..:...||:.|.::.|:|.:||....:.:|:.:|....|.:||||.||||:||
 Frog  1321 PENYKGLLSP--TQIPPNWPENGEIQIQNLSVRYDSSLKPVLKHVNAHITPGQKIGICGRTGSGK 1383

  Fly  1088 SSIIQALFRLA-LNEGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTLRFNLDPFDEKSDES 1151
            ||...|.||:. ..:|.|.|||:||.||.|..||||:|||.|||:|||||:||||||.::.:|..
 Frog  1384 SSFSLAFFRMVDTFQGRIIIDGIDIAKLPLQTLRSRLSIILQDPILFSGTIRFNLDPENKCTDAM 1448

  Fly  1152 LWSALDDVKLKKHVASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNRVLVMDEATANVDTE 1216
            ||.||:..:||..|..|.|||...:.:||.|||:|||||.|||||.:|::.:|:||||||::|..
 Frog  1449 LWEALEIAQLKHVVKVLPGGLDALVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMA 1513

  Fly  1217 TDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHKLLQ 1269
            |:.::|:.:.|.|.:.||:|||||:||:::.|.|:||..|.|:|:..|..||:
 Frog  1514 TENILQKVVMTAFDDRTVVTIAHRVHTILNADLVIVMKRGAIMEYDKPEALLE 1566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	403/1418 (28%)
abcc8	XP_031756190.1	MRP_assoc_pro	224..1573	CDD:188098	400/1412 (28%)