Protein Alignment CG10505 and abcc6

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_002932264.3
• Gene: abcc6 / 100493037
• XenbaseID: XB-GENE-6465366
• Length: 1500
• Species: Xenopus tropicalis
• Alignment Length: 1344
• Identity: 429/1344 - (31%)
• Similarity: 691/1344 - (51%)
• Gaps: 132/1344 - (9%)

  Fly     7 SSPKRESN--PFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRNLQPHWEK 69
            |:.|:|||  |..:::.:||..|.|...:..:|.::.|.|..::....|..:|.:........||
 Frog   197 SNLKKESNPCPVSESSFLSKVTFSWFTEIMFRGYKQPLKAEDVWSLRKSDTAEEILTLFSKGVEK 261

  Fly    70 ESKKKN---------PS-------------------------------LMRLIFKVYGWQFVPVC 94
            |.||.|         ||                               |:::|.:.:|
 Frog   262 ECKKANLLKEPTRFSPSTLDNDMWISQTEKSEIELLLKNQHIQLSQKTLLKVIMRSFG------- 319

  Fly    95 ILYSLLEMAIHSF-------QPLLLGGLISYFAYGQTTVTKESAYLYAMGIVLCSLVTSLVFHPF 152
             ||.||...:.:|       .|||:..|:....  ..:......:|.|:.:.:|....||..|..
 Frog   320 -LYFLLSALLMTFYTAFLFISPLLVRLLLQLLK--DPSAPSWQGFLVAVFLFICPCCQSLFLHQH 381

  Fly   153 MFYVFAVGTRVRLACAGLVYRKCLR-ASASSGEGLGGQAISVMSIDLSQ-FDLTFYFFHDLWKGP 215
            .:..:.:|.|:|.|..|.||:|.|. :||...|...|:.::::|.|:.: .||.....: :|..|
 Frog   382 DYICYVIGMRLRAAIVGTVYKKALMISSAGRKESSAGEIVNLISTDVQKLMDLATCVNY-MWSAP 445

  Fly   216 VEACIFGYLMTRQVGWTSLIGIAFIVILIPLQAWAAKASASFGTRSAKHRDARVKLMNEIIGAIQ 280
            |...:..|.:.:.:|...|.|:|..::.:|.....|........:..|.:|.|:|:::||:..|:
 Frog   446 VTIIVAMYFLWQTLGIAVLAGVAVFILNLPFMTVFAVIIKRVQEQQMKQKDGRIKIISEILQGIK 510

  Fly   281 VIKMYAWEKSFGRLIAAVRQSEVKAIR-------GSMSIYAALQCTNMISKISLFLSLVAYVYVG 338
            |:|:||||.:|.:.:...|..|:||::       |:::::.|......::...:||:|..    .
 Frog   511 VLKLYAWENAFMKKVTEFRLMELKAVKTGALLLSGALAVFVASPFWVSLTMFGVFLALDE----K 571

  Fly   339 DLVTAKKVFILSSYYGLLNDSLLHYWPMAITTWAQTLVSARRVVEFLLQVEKPTEESCCRDNPGL 403
            :::.|:|.|:......:|... |..:|||||.:||:.||.:|:|:|....|...|        .:
 Frog   572 NILDAEKAFVTIILLNILRIP-LRMFPMAITLFAQSSVSLKRMVKFFSAEELEPE--------SV 627

  Fly   404 ELDAEKPKPAQSGRLHCVQSETKCLSFRKVSASWDKPSIKQPRKPHIEGISFHINAGQFVGIVGN 468
            :::....|.|              ::.|..:.:|   |..:|  |.::.|:..|..|..|.:||.
 Frog   628 DINDSLSKHA--------------ITIRHGTFTW---SSSEP--PCLQSINIGIPQGTLVAVVGQ 673

  Fly   469 VGSGKSTLLHAILGEIELMQGRVEVHGRISYAAQQPWVFQGSIRENILFVEQYEEKRYRAVVHAC 533
            ||.||::||.|:|||:|.::|:|.:...::|..||.|:...:.:||:||..:.|:..|..||.||
 Frog   674 VGCGKTSLLSALLGEMEKVEGQVSLMSSVAYVPQQTWIPNATFKENVLFGRKMEKCWYDQVVQAC 738

  Fly   534 QLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYRQADIYLFDDPLAAVDAQVGKLLMDK 598
            .|..||::|..|:.|.:||:|::||||||.||::||||||..|:||.||||:||||.||:.|.::
 Frog   739 ALLPDLKILSGGENTEIGEKGVNLSGGQKQRISIARAVYRNCDVYLLDDPLSAVDAHVGQHLFEQ 803

  Fly   599 CF--HRLLDGKMRILVTHHVQLLKSVDQLLLLEGGKLTQQGSYEEL-------KDVITHHAALDL 654
            ..  ..||..|.|:||||.|..|..:|.::::..|::::.|:|.||       .:.:..:|...:
 Frog   804 VIGPSGLLKDKTRVLVTHGVSFLPQMDMIIVMSDGRVSEVGTYNELLQKNGAFSEFLNTYARKSV 868

  Fly   655 EAIEADKQQVKRVLSQVDRTSKQLSKGEEKDPAT------IQDENG---NAEQQLQGAVSYDTYK 710
            ...|:.::|....:....:...:.|...:.|..|      |:.:.|   .|:..|.|.|....|.
 Frog   869 VFEESYEEQTPNSIQGAMKMKGKHSARNDTDNETDDVANEIEADAGKLTEADVALTGRVKLSVYL 933

  Fly   711 AYFRALGAPFLVCLVLSMFVLARGCQAVMDIFISRWATWEEDRGYDSVDDYEATRTKMVIWYTVL 775
            .|.:.:|..:|:...| .|::.:......:.:|..||   :|...:....:.:.|..:..:..|:
 Frog   934 EYCKIMGKWYLLISAL-FFIVQQAASLSYNYWIGLWA---DDPPVNGTQQHTSLRLGVYSFLGVM 994

  Fly   776 LLLTL--ALFLLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFFNANPSGRVLNRFSSDIQNVDV 838
            ..|::  |...:...|     :.:|..||.:|.:.|:|..:.||...|||.:.|||:.::..:|.
 Frog   995 QALSIFAASSTIIVGG-----VSVSRQLHSRLLYSILRCPLSFFERTPSGNLTNRFAKEMDIIDN 1054

  Fly   839 NLPQAMMDSLQFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFCRALYIGASRSLKRIESLTRSP 903
            .:||.:|..:..::.:..:|::::||.....:....:.:|.:|.:..|:.:||.|||::::::||
 Frog  1055 TVPQVLMLFIIMMLTIAEILLVISIATPLAAVAFIPLGLLYFFLQRFYVASSRQLKRLDAVSKSP 1119

  Fly   904 IYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVSANRAFSFWTDLICVIYILAVT 968
            :|:|.|::..|...||:.....:..|..:...|.|....|....|||..|...|.:....:..|.
 Frog  1120 LYTHFNESLQGVYVIRAFREQERFIQDNNMRLNMNQRFYFCSFVANRWLSVRCDFLSNFIVFTVA 1184

  Fly   969 FSFLVINQSFYSGDVGLAITQSMTLVIMCQWGMRQTAEMENNMTSVERVLEYAQTPSEPPLESPK 1033
            ...::...:...|.||||:..|:.|..:.:..:....:||.|..|||||.||.....|.|..|..
 Frog  1185 IVGVLFRDNITPGLVGLAVVNSLRLTGVLKEAVHVATDMETNSVSVERVKEYCDAEPEAPWTSDN 1249

  Fly  1034 SVNLAAEWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPMEKIGIVGRTGAGKSSIIQALFR-L 1097
            :.:| :.||..|.:.||:..:||.|..:..|:.:....|..||:||||||||||||:...||| |
 Frog  1250 ASDL-SNWPSKGKIEFQNYGLRYRPDLDLALKNVTASIQQGEKVGIVGRTGAGKSSLTLGLFRIL 1313

  Fly  1098 ALNEGTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGTLRFNLDPFDEKSDESLWSALDDVKLK 1162
            ....|.|.||..||.:||||:|||:|:||||||||||||||.||||||..||..:|.||....||
 Frog  1314 EPATGRICIDEKDISELGLHELRSKITIIPQDPVLFSGTLRMNLDPFDNYSDNDIWVALQLAHLK 1378

  Fly  1163 KHVASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQNRVLVMDEATANVDTETDILIQETIQT 1227
            ...:.|..|||....:||.|.|:|||||||||||:||:.::||:|||||.||.|||.|||.||:.
 Frog  1379 VFASGLPEGLSYICTEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQNTIRK 1443

  Fly  1228 KFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHKLLQRK 1271
            :|.:||::||||||:|:||...|:|.|.|:||||..|..||:.|
 Frog  1444 EFEDCTIITIAHRLNTIMDYTRVVVFDKGEIVEFDTPATLLENK 1487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	423/1332 (32%)
abcc6	XP_002932264.3	MRP_assoc_pro	5..1499	CDD:188098	429/1344 (32%)