Protein Alignment CG10505 and abcc1

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_031748377.1
• Gene: abcc1 / 100145582
• XenbaseID: XB-GENE-960171
• Length: 1525
• Species: Xenopus tropicalis
• Alignment Length: 1383
• Identity: 457/1383 - (33%)
• Similarity: 716/1383 - (51%)
• Gaps: 185/1383 - (13%)

  Fly    15 PFIKANIISKWLFLWMHSVFRKGRREELDASKLYEHLPSFDSESLTRNLQP----HWEKE----- 70
            |...|:.:|:..|.|:..:..:|.:..|:|..|:    |.:.|..:..:.|    :||||
 Frog   207 PESSASFLSQITFWWISRMMVQGFKRPLEAKDLW----SLNKEDKSLEVVPVLSKNWEKEYNKAK 267

  Fly    71 ---------------SKKKN----------------------PSLMRLIFKVYGWQFVPVCILYS 98
                           :||.|                      |||::.::|.:|..|...|....
 Frog   268 AKKVPLKMVYSPKKQTKKLNSKEDVREEAEALIVKPAPKELEPSLLKALYKTFGPYFFISCFFKF 332

  Fly    99 LLEMAIHSFQPLLLGGLISYFAYGQTTVTKESAYLYAMGIVLCSLVTSLVFHPFMFYVFAVGTRV 163
            ..::.:.| .|.||..||.:  .|.........|||...:..|:.:.:|:.|.:....|..|.|:
 Frog   333 FHDVLMFS-GPQLLQLLIKF--VGDKDAPDWHGYLYTFLLFFCACLQTLILHKYFHICFVTGMRL 394

  Fly   164 RLACAGLVYRKCL------RASASSGEGLGGQAISVMSIDLSQF-DLTFYFFHDLWKGPVEACIF 221
            :.|..||||||.|      |.:::.||     .:::||:|..:| ||..| .:.:|..|::..:.
 Frog   395 KTAVVGLVYRKALVINNSARRTSTIGE-----IVNLMSVDAQRFMDLATY-INMIWSAPLQVILA 453

  Fly   222 GYLMTRQVGWTSLIGIAFIVILIPLQAWAAKASASFGTRSAKHRDARVKLMNEIIGAIQVIKMYA 286
            .||:.:.:|.:.|.|||.:|:|:|:.|..|..:..:.....|.:|.|:||||||:..|:|:|:||
 Frog   454 FYLLWQNLGPSVLAGIAVMVLLVPVNAVIAMKTKKYQVVQMKCKDNRIKLMNEILNGIKVLKLYA 518

  Fly   287 WEKSFGRLIAAVRQSEVKAIRGSMSIYAALQCTNMISKISLFLSLVAYVYV----GDLVTAKKVF 347
            ||.:|...:..:|:.|:|.::.|..:.|....|.:.:...:.||..| |||    .:::.|:|.|
 Frog   519 WELAFKEKVLGIRKDELKVLKKSAYLAAVGTFTWVCAPFLVALSTFA-VYVLIDKQNVLDAEKAF 582

  Fly   348 ILSSYYGLLNDSLLHYWPMAITTWAQTLVSARRVVEFLLQVEKPTEESCCRDNPGLELDAEKPKP 412
            :..:.:.:|... |:..||.|::..|..||.:|:..||.. |:...||..|:          |:.
 Frog   583 VSLALFNILRFP-LNMLPMVISSMVQASVSLKRLRVFLSH-EELEPESIIRE----------PQK 635

  Fly   413 AQSGRLHCVQSETKCLSFRKVSASWDKPSIKQPRKPHIEGISFHINAGQFVGIVGNVGSGKSTLL 477
            :..|          .::.:..:.||.:..:     |.::.|:..|..|..|.:||.||.|||:||
 Frog   636 SSEG----------SINMKDATFSWSRNDL-----PSLKDINISIPEGSLVAVVGQVGCGKSSLL 685

  Fly   478 HAILGEIELMQGRVEVHGRISYAAQQPWVFQGSIRENILFVEQYEEKRYRAVVHACQLDRDLELL 542
            .|:|||:|...|.|.:.|.:.|.:||.|:...|:::|:||..:..|..|:.|:.||.|..|||:|
 Frog   686 SALLGEMEKQDGYVAMKGSVGYVSQQAWIQNASLKDNVLFGRESNESMYKKVIEACALLPDLEIL 750

  Fly   543 PRGDATVVGERGISLSGGQKARIALARAVYRQADIYLFDDPLAAVDAQVGKLLMDKCF--HRLLD 605
            |.||.|.:||:|::||||||.|::||||||...||||.||||:||||.|||.:.||..  ..:|.
 Frog   751 PTGDRTEIGEKGVNLSGGQKQRVSLARAVYCNTDIYLLDDPLSAVDAHVGKHIFDKVIGPKGMLK 815

  Fly   606 GKMRILVTHHVQLLKSVDQLLLLEGGKLTQQGSYEEL-------KDVITHHAAL----DLEAIEA 659
            .|.||||||.|..|..:|.::::..||:|:.|||::|       .:.:..:|..    |.||...
 Frog   816 NKTRILVTHGVSYLPQMDSIIVMVDGKITEVGSYQDLLMQDGAFAEFLRTYANAEQNKDQEANTT 880

  Fly   660 DKQQVKRVLSQVDRTSKQLSKGEEKDPATIQ------------------DENGN---------AE 697
            :.::.:...|.|....|:|..|..::...:|                  |.|.:         |:
 Frog   881 EVEEEEEAPSPVPSEEKRLENGILRNERNLQRQLSASSETKSLNQNKTGDLNSSEKDDWKLTEAD 945

  Fly   698 QQLQGAVSYDTYKAYFRALGAPFLVCLVLSMFVLARGCQAVMDIFISRW-ATWEEDRGYDSVDDY 761
            :...|.|....:..|.:|:|. ||..|.:.:|:    |..|..:..:.| :.|.:|:..:.....
 Frog   946 KAKTGRVKLAVFWEYMKAIGL-FLCFLSIFLFM----CNHVASLASNYWLSLWTDDKVVNGTQQN 1005

  Fly   762 EATRTKM---------VIWYTVLLLLTLALFLLRTFGFFFMCLRISLTLHDQLYHGIIRAWMYFF 817
            ...|..:         :..|.....::|...|...|            ||..|.|.::|..|.||
 Frog  1006 TTMRLSVYGALGFSQGIAVYGYSTAVSLGGILASRF------------LHTDLLHNVLRFPMSFF 1058

  Fly   818 NANPSGRVLNRFSSDIQNVDVNLPQAMMDSLQFLVDVVAVLVIVAIANYWLLIPAAIMVILLYFC 882
            ...|||.::||||.:|..:|..:||.:...:..|.:|:...||:..|...:.:....:.::.:|.
 Frog  1059 ERTPSGNLVNRFSKEIDTIDNTIPQIIKMFMGSLFNVIGACVIILTATPIVAVIIPPLGLVYFFV 1123

  Fly   883 RALYIGASRSLKRIESLTRSPIYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQNTNSSALFLYVS 947
            :..|:..||.|||:||::|||:|||.|:|..|.|.||:.....:..|......:.|..|.:..:.
 Frog  1124 QRFYVATSRQLKRLESVSRSPVYSHFNETLLGSSVIRAFGEQKRFIQISDFKVDENQRAYYPSIV 1188

  Fly   948 ANRAFSFWTDLI--CVIYILAVTFSFLVINQSFYS-GDVGLAITQSMTLVIMCQWGMRQTAEMEN 1009
            :||..:...:.:  |::...::   |.||:::..| |.|||:::.::.:.....|.:|.::|:|.
 Frog  1189 SNRWLAIRLEFVGNCIVLFASL---FAVISRTTLSPGLVGLSVSYALQVTTYLNWLVRMSSELET 1250

  Fly  1010 NMTSVERVLEYAQTPSEPPLESPKSVNLAAEWPQAGHLRFQDLRMRYSPGDEDILRGLNFESQPM 1074
            |:.:||||.|||....|......::.. .|.||..|.:.|:...:||....:..|:.:|...|..
 Frog  1251 NIVAVERVKEYADLKQEAAWTVQETAP-EATWPHEGKIEFRGYGLRYREDLDLALKNINVTIQGG 1314

  Fly  1075 EKIGIVGRTGAGKSSIIQALFRLALNE---GTIEIDGLDIGKLGLHDLRSRISIIPQDPVLFSGT 1136
            ||:||||||||||||:...|||  :||   |.|.|||.::.|:||||||.|::||||||||||||
 Frog  1315 EKVGIVGRTGAGKSSLTLGLFR--INEAAAGEIVIDGCNLAKIGLHDLRFRVTIIPQDPVLFSGT 1377

  Fly  1137 LRFNLDPFDEKSDESLWSALDDVKLKKHVASLEGGLSCRMQDGGSNFSMGQRQLVCLARAILRQN 1201
            ||.||||||:.:|:.:|::|:...||:.||:|...|:....:||.|.|:|||||||||||:||:.
 Frog  1378 LRMNLDPFDKYTDDDIWTSLELAHLKRFVANLPDRLNHECAEGGENLSIGQRQLVCLARALLRKT 1442

  Fly  1202 RVLVMDEATANVDTETDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAGQIVEFGAPHK 1266
            ::||:|||||.||.|||.|||.||:.:|.:|||:||||||:|:||...|:|:|.||:|||.:|..
 Frog  1443 KILVLDEATAAVDLETDGLIQSTIRKEFQDCTVITIAHRLNTIMDYTKVIVLDKGQVVEFDSPSN 1507

  Fly  1267 LLQR--------KDGALL 1276
            |||:        ||..|:
 Frog  1508 LLQQQGIFFNMAKDSGLV 1525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	454/1376 (33%)
abcc1	XP_031748377.1	MRP_assoc_pro	5..1524	CDD:188098	456/1380 (33%)