Protein Alignment CG10505 and abcc5

DIOPT Version :10

• Sequence 1: NP_611571.2
• Gene: CG10505 / 37428
• FlyBaseID: FBgn0034612
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_012818083.1
• Gene: abcc5 / 100125060
• XenbaseID: XB-GENE-986260
• Length: 1437
• Species: Xenopus tropicalis
• Alignment Length: 1381
• Identity: 432/1381 - (31%)
• Similarity: 716/1381 - (51%)
• Gaps: 177/1381 - (12%)

  Fly    11 RESNPFIKANIISKWLFLWM----HSVFRKGRREELDASKLYEHLPSFDSESLTRNLQPHWEKES 71
            :..:|...|.:.|...|.|:    ...::||.....|...|.:| .|.|..|  :.|:..|.:|.
 Frog    97 KHQHPVDNAGLFSFMTFSWLTPMARIAYKKGELFFEDIWPLSKH-ESSDINS--KRLEKLWLEEV 158

  Fly    72 KKK--NPSLMRLIFKVYGWQFVPVCILYSLLEMAIHSFQPLLLGGLI-------SYFAYGQTTVT 127
            .:|  :.|.:|.:.    |.|....::.|::.:.:..     |.|.|       |...|.|.: :
 Frog   159 TEKGADESSLRSVV----WHFCRTRLIISIMCLMLTQ-----LAGFIGPAFVVKSLLEYTQQS-S 213

  Fly   128 KESAYLYAMGIVLCSLVTSLVFHPFMFYVFAV----GTRVRLACAGLVYRKCLRASASSGEGLGG 188
            |:..  |::.:|...|:|.:|....:...:|:    |:|:|.|...:.::|.|:......:.: |
 Frog   214 KDPG--YSLLLVFALLMTEIVRSWSLALTWALNYRTGSRLRGAVLTMAFKKILKLKNIKEKSM-G 275

  Fly   189 QAISVMSIDLSQFDLTFYFFHDLWKGPVEA---CIFGYLMTRQVGWTSLIGIAFIVILIPLQAWA 250
            :.|:|.|.|..:..........|..||:.|   .|:..::   :|.|..:|.|..::..|...:.
 Frog   276 ELINVCSSDGQRMFEAAAVGSLLAGGPIVAILGMIYNVII---LGPTGFLGSAVFILFYPAMMFV 337

  Fly   251 AKASASFGTRSAKHRDARVKLMNEIIGAIQVIKMYAWEKSFGRLIAAVRQSEVKAIRGS---MSI 312
            ::.:|.|..:.....|.||:.|||::..|:.||||||.|:|.:.:..:|::|...:..:   .||
 Frog   338 SRLTAYFRRKCVSVTDERVQKMNEVLNYIKFIKMYAWVKAFSQNVQKIRENERSILERAGYFQSI 402

  Fly   313 YAALQCTNMISKISLFLSLVAYVYVGDLVTAKKVFILSSYYGLLNDSLLHYWPMAITTWAQTLVS 377
            ...:  ..::..|:..|:...::.:|..:||.:.|.:.:.:..:..: |...|.::.:.::..||
 Frog   403 TVGI--APIVVVIASVLTFSVHMILGYDLTAAQAFTVVTVFNSMTFA-LKVTPFSVKSLSEASVS 464

  Fly   378 ARRVVEFLLQVE------KPT------------------------------------------EE 394
            ..|.....|..|      ||:                                          :|
 Frog   465 MDRFKSLFLMEEVHMVKKKPSSPNLIIELKNATLAWDTTYASTQCSPKGTPKLKKGKKGVKGKKE 529

  Fly   395 SCCRDNPG-----------LELDA-EKPKPAQSGRLHCVQSETKCLSFRKVSASWDKPSIKQPRK 447
            .|..:..|           |.:|: |.|.|         ..|||           :.|.|....:
 Frog   530 KCSHEIEGSQAVLAEQKGHLLIDSDEHPSP---------DEETK-----------ELPVINVKLQ 574

  Fly   448 PHIEGISFHINAGQFVGIVGNVGSGKSTLLHAILGEIELMQGRVEVHGRISYAAQQPWVFQGSIR 512
            ..:..|...|..|:.:||.|:|||||::|:.||||::.|::|.:.|.|..:|.|||.|:...::|
 Frog   575 RALYSIDLDIEKGKLIGICGSVGSGKTSLISAILGQMTLLEGSIAVSGSFAYVAQQAWILNATLR 639

  Fly   513 ENILFVEQYEEKRYRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYRQADI 577
            :||||.::::|:.|.||::.|.|..||.:||.||.|.:||||.:|||||:.||:||||:|....|
 Frog   640 DNILFGKEFDEEEYNAVLNVCCLRPDLAILPNGDLTEIGERGANLSGGQRQRISLARALYSDRSI 704

  Fly   578 YLFDDPLAAVDAQVGKLLMDKCFHRLLDGKMRILVTHHVQLLKSVDQLLLLEGGKLTQQGSYEEL 642
            |:.||||:|:||.||..:.:....:.|..|..:.:||.:|.|...|.::.::.|.:|::|::|:|
 Frog   705 YILDDPLSALDAHVGNHIFNSAIRKHLKSKTILFITHQLQYLVDCDDVIYMKEGCITERGTHEDL 769

  Fly   643 KDVITHHAAL-------DLEAIEADKQQVKRVLSQVDRTSKQLSKGEE----KDPATIQDENG-- 694
            ..:...:||:       |...||  :..:|:.|.  :...|.|.||.:    |...|::.|.|
 Frog   770 IKLNGEYAAIFNNFQLGDAPHIE--QMNLKKNLK--NSLKKPLEKGNKAGSVKKEKTVKKEEGQL 830

  Fly   695 -NAEQQLQGAVSYDTYKAYFRALGAPFLVCLVLSMFVLARGCQAVMDIFISRWATWEEDRGYDSV 758
             ..|::.:|:|.:..|.||.::.|.||...:::::|||..|..|..:.::|.|.  ::..|..:|
 Frog   831 MQLEEKGKGSVPWSVYGAYIQSAGGPFAFLIIMTLFVLNVGSTAFSNWWLSYWI--KQGSGNTTV 893

  Fly   759 DDYEAT-------RTKMVIWYTVLLLLTLALFLL----RTFGFFFMCLRISLTLHDQLYHGIIRA 812
            ..:..|       ....|::||.:..|::.:.||    |...|....||.|..|||:|:..|:|:
 Frog   894 VVHNETVVSNSMKDNPHVLFYTAIYALSMVVMLLLKAVRGIVFVKGTLRASSRLHDELFRRILRS 958

  Fly   813 WMYFFNANPSGRVLNRFSSDIQNVDVNLP-QAMMDSLQFLVDVVAVLVIVAIANY---WLLI--- 870
            .|.||:..|:||||||||.|:..|||.|| ||.|    |:.:|:.|...:.:.::   |.|:
 Frog   959 PMKFFDTTPTGRVLNRFSKDMDEVDVRLPFQAEM----FVQNVILVFFCLGVISFVFPWFLVAVG 1019

  Fly   871 PAAIMVILLYFCRALYIGASRSLKRIESLTRSPIYSHTNQTFHGHSTIRSMDAMPQLEQTFHGHQ 935
            |..::..:|:....::|   |.|||:|::|:||..||...:..|.:||.:.....:....:....
 Frog  1020 PLVVLFTILHVVSRVFI---RELKRLENITQSPFLSHITSSIQGLTTIHAYSKGNEFLLRYQELL 1081

  Fly   936 NTNSSALFLYVSANRAFSFWTDLICVIYILAVTFSFLVINQSFYSGDVGLAITQSMTLVIMCQWG 1000
            :.|.:..:|:..|.|..:...|:|.|..|.......::::.:......|||::.::.|..:.|:.
 Frog  1082 DNNQAPFYLFNCAMRWLAIRLDVISVSLITTTGLMIVLMHGNISPAYAGLAMSYAVQLTGLFQFT 1146

  Fly  1001 MRQTAEMENNMTSVERVLEYAQTPSEPPLESPKSV-NLA--AEWPQAGHLRFQDLRMRYSPGDED 1062
            :|..:|.|...|||||:..|.:|.:   ||:|..: |.|  |:|||.|.::|::..|||......
 Frog  1147 VRLASETEARFTSVERINHYIKTLA---LEAPARIKNKAPPADWPQEGEIKFENAEMRYRENLPL 1208

  Fly  1063 ILRGLNFESQPMEKIGIVGRTGAGKSSIIQALFRLA-LNEGTIEIDGLDIGKLGLHDLRSRISII 1126
            :|:.::|..:|.||||||||||:||:|:..|||||. |:.|.|:|||:.|..:||.||||::|||
 Frog  1209 VLKKVSFTIKPKEKIGIVGRTGSGKTSLGMALFRLVELSGGCIKIDGVKISDIGLADLRSKLSII 1273

  Fly  1127 PQDPVLFSGTLRFNLDPFDEKSDESLWSALDDVKLKKHVASLEGGLSCRMQDGGSNFSMGQRQLV 1191
            ||:|||||||:|.|||||.:.|:|.:|.||:...:|:.||.|...|...:.:.|.|||:|:|||:
 Frog  1274 PQEPVLFSGTVRSNLDPFSQYSEEQIWDALERTHMKECVAQLPLKLETEVLENGENFSVGERQLM 1338

  Fly  1192 CLARAILRQNRVLVMDEATANVDTETDILIQETIQTKFAECTVLTIAHRLHTVMDNDSVLVMDAG 1256
            |:||.:||:.::|::|||||.:|||||:||||||:..|||||:||||||||||:..|.::|:..|
 Frog  1339 CIARVLLRRCKILILDEATAAMDTETDLLIQETIREAFAECTMLTIAHRLHTVLSCDRIMVLAQG 1403

  Fly  1257 QIVEFGAPHKLLQRKD 1272
            |::|:..|..||..::
 Frog  1404 QVMEYDTPSALLSNEN 1419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10505	NP_611571.2	MRP_assoc_pro	15..1271	CDD:188098	432/1374 (31%)
abcc5	XP_012818083.1	PLN03130	101..1425	CDD:215595	432/1377 (31%)