Protein Alignment MFS16 and SLC37A3

DIOPT Version :9

• Sequence 1: NP_726048.1
• Gene: MFS16 / 37427
• FlyBaseID: FBgn0034611
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_996996.1
• Gene: SLC37A3 / 84255
• HGNCID: 20651
• Length: 494
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 174/504 - (34%)
• Similarity: 268/504 - (53%)
• Gaps: 37/504 - (7%)

  Fly    79 RRDLLYKMS-----VFVLTFLAYACYHMCRKPISVVKSVLQG-------NCSTALAASGQDCGYA 131
            |..||.:.|     ||:|||.:|:..|..||..|.||..:..       |.|..|........:.
Human     9 RGSLLSQFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISEQWTPSAFNTSVELPVEIWSSNHL 73

  Fly   132 PFDVPDATTLFGMLDSAFLFSYAIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFG-IARTSNI 195
            ......||...|.||:.||||||:.:|.||.|.:|::||:.||.||..:.:..::|| :......
Human    74 FPSAEKATLFLGTLDTIFLFSYAVGLFISGIVGDRLNLRWVLSFGMCSSALVVFVFGALTEWLRF 138

  Fly   196 HSLWYFIIVQIFAGIFQTTGWPGVVALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVES 260
            ::.|.:..:.|..|:.|:||||.|||::|.||||:.||::||:|::..|:|||||..:|:..::.
Human   139 YNKWLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQY 203

  Fly   261 DWALSFVVPGIIIAAVGFLLFLFLVDQPEIVGCYPQAGQHERRVANESDVEQDDEEQVRHNDAEI 325
            .:..:|:|...:..|.|.::|..|:..||.:|.   :|     :..|.:.|:|....:      |
Human   204 GYEYAFLVTASVQFAGGIVIFFGLLVSPEEIGL---SG-----IEAEENFEEDSHRPL------I 254

  Fly   326 NYRSAPTERTPILPRSQPEAVPRGRGRPISLIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYI 390
            |......|..|........:|  .:.:.||...|..:|||:.:||.....|||:|:|.:|||.|:
Human   255 NGGENEDEYEPNYSIQDDSSV--AQVKAISFYQACCLPGVIPYSLAYACLKLVNYSFFFWLPFYL 317

  Fly   391 QKSSTLG-PELSAD-LSTLFDVGGILGAIAAGYLSDVSGMSATVCTGMLFVASPILLMYQQYGAL 453
              |:..| .|..|| ||..:|||||:|....|::|||....|.|....|.:|...|:.|.: ...
Human   318 --SNNFGWKEAEADKLSIWYDVGGIIGGTLQGFISDVLQKRAPVLALSLLLAVGSLIGYSR-SPN 379

  Fly   454 SMTISIVLLIVVGIFVNGPYALITTSVSAELGQHSSLEGNANALATVTAIIDGTGSIGAAVGPLL 518
            ..:|:.:|:.|.|.|:.||..:|::::||:||:...::.::.||||||.|:||:||||||||..|
Human   380 DKSINALLMTVTGFFIGGPSNMISSAISADLGRQELIQRSSEALATVTGIVDGSGSIGAAVGQYL 444

  Fly   519 AGLI-STAGWQYVFHMLIAADIIAMVLLGRLVFKEF--AALRRASHRIR 564
            ..|| ...||.:||:..|......:|.:..|:.:|.  ..|||.:|.:|
Human   445 VSLIRDKLGWMWVFYFFILMTSCTIVFISPLIVREIFSLVLRRQAHILR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS16	NP_726048.1	UhpC	84..545	CDD:225180	164/476 (34%)
		MFS	139..549	CDD:119392	147/413 (36%)
SLC37A3	NP_996996.1	UhpC	14..479	CDD:332119	165/483 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148743
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2533
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57781
OrthoDB	1	1.010	-	-		D292288at33208
OrthoFinder	1	1.000	-	-		FOG0000756
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100970
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.660