DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS16 and G3Pp4

DIOPT Version :9

Sequence 1:	NP_726048.1	Gene:	MFS16 / 37427	FlyBaseID:	FBgn0034611	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_193488.2	Gene:	G3Pp4 / 827470	AraportID:	AT4G17550	Length:	544	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	234/545 - (42%)
Similarity:	326/545 - (59%)	Gaps:	72/545 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 NNYNDVPFGIRAVQRLSRQCCTRFHARRDLLYKMSVFVLTFLAYACYHMCRKPISVVKSVLQGNC 117
            |:....|.||..::|:      |........::.::..:||:||||||..|||.|:|||||..:.
plant     4 NSKRKTPPGIALLRRV------RGRNWSPKTFRYAILFITFIAYACYHASRKPSSIVKSVLHPDS 62

  Fly   118 ST-----------------------------ALAASGQDCGYAPFDVPDATTLFGMLDSAFLFSY 153
            ||                             .:....:..|:.||:..|.|:..|.:|.|||..|
plant    63 STKPPQEHNSDKIYPWPMGNVFVKREIGDIDEVLLHRKSKGWEPFNGKDGTSRLGEIDVAFLACY 127

  Fly   154 AIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYFIIVQIFAGIFQTTGWPG 218
            :|.|:.:|.:.:.:.||.||:.|||.:|.|..:||:....|||:.|:|:::|:.||:||.||||.
plant   128 SIGMYVAGHLGDSLDLRLFLTWGMIGSGFFVGLFGMGYFWNIHAFWFFLVMQMAAGLFQATGWPS 192

  Fly   219 VVALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVESDWALSFVVPGIIIAAVGFLLFLF 283
            |||:||.||||.|||||.||||:|||:|||.|:||||..:|..|..||:.||.:::..|.|::||
plant   193 VVAVVGNWFGKRKRGLIMGIWNAHTSVGNICGSLIAAGVLEYGWGWSFIAPGFVMSLGGVLVYLF 257

  Fly   284 LVDQPEIVGCYPQAGQHERR-VANESDVEQDDEEQVR------HNDAEINYRSAPTERTPILPRS 341
            |...||.|| :|....:..: :..:.|||:::||...      ..|.|.:..|
plant   258 LAAYPEDVG-FPDINSNSGKFIKRKRDVEEEEEEVEEDLGTDVEGDGEGSSGS------------ 309

  Fly   342 QPEAVPRGRG----RPISLIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYIQKSSTLGPE--- 399
                   |.|    |.:.|:.|..||||:.|:|||||:|||:|||:||||.|:.: :|:|.|
plant   310 -------GSGYENKRSVGLLQACMIPGVIPFALCLFFSKLVAYTFLYWLPFYLSQ-TTIGGEYVS 366

  Fly   400 --LSADLSTLFDVGGILGAIAAGYLSDVSGMSATVCTGMLFVASPILLMYQQYGALSMTISIVLL 462
              .:.:||||||||||:|.|..||:||.....||.....::.|.|.:|:|..||.:|.|::|:|:
plant   367 VKTAGNLSTLFDVGGIVGGILCGYISDKFKARATTAAAFMYAAIPAMLVYHSYGGVSQTVNILLM 431

  Fly   463 IVVGIFVNGPYALITTSVSAELGQHSSLEGNANALATVTAIIDGTGSIGAAVGPLLAGLISTAGW 527
            :|.|:|||||||||||:|||:||.|.||:|::.||||||||||||||.|||:||||.|.:||.||
plant   432 MVAGLFVNGPYALITTAVSADLGTHKSLQGDSRALATVTAIIDGTGSAGAALGPLLTGFLSTLGW 496

  Fly   528 QYVFHMLIAADIIAMVLLGRLVFKE 552
            |.||:||:...:.|.:||.|||..|
plant   497 QAVFYMLVVGALCAGLLLTRLVIAE 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS16	NP_726048.1	UhpC	84..545	CDD:225180	222/505 (44%)
MFS16	NP_726048.1	MFS	139..549	CDD:119392	202/425 (48%)
G3Pp4	NP_193488.2	MFS_SLC37A1_2	30..521	CDD:340902	227/511 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	309	1.000	Domainoid score	I315
eggNOG	1	0.900	-	-		E2759_KOG2533
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	428	1.000	Inparanoid score	I423
OMA	1	1.010	-	-		QHG57781
OrthoDB	1	1.010	-	-		D964162at2759
OrthoFinder	1	1.000	-	-		FOG0000756
OrthoInspector	1	1.000	-	-		otm2934
orthoMCL	1	0.900	-	-		OOG6_100970
Panther	1	1.100	-	-	LDO	PTHR43184
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840