DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS16 and slc17a7

DIOPT Version :9

Sequence 1:	NP_726048.1	Gene:	MFS16 / 37427	FlyBaseID:	FBgn0034611	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	562	Identity:	110/562 - (19%)
Similarity:	205/562 - (36%)	Gaps:	133/562 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 HLHLAHCPRRSMRASLGLGRTRKMSNNYNDVPFGIRAVQRLSRQCCTRFH-ARRDLLYKMS--VF 89
            |||      |.:......|.|.:::.....|   |:..:|.....||.|. .||.::..||  .|
Frog    18 HLH------RILEKKQTNGETIELTEEGRPV---IKEEKRQPVVDCTCFGLPRRYIIAIMSGLGF 73

  Fly    90 VLTFLAYACYHMCRKPISVVKSVLQGNCSTALAASGQDCGYAPFDVPDATTLFGMLDSAFLFSYA 154
            .::|..     .|...:::|..|   |.:|....:......|.|.....|.  ||:..:|.:.|.
Frog    74 CISFGI-----RCNLGVAIVSMV---NNNTVYKGNKIVIEQAQFTWDPETV--GMIHGSFFWGYI 128

  Fly   155 IAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYFIIVQIFAGIFQTTGWPGV 219
            :.....|::.::.:........::.|.....:  |...:.:| ....|.|:|..|:.:...:|..
Frog   129 VTQIPGGYICQKFAANRVFGFAIVATSTLNML--IPSAARVH-FACVICVRILQGLVEGVTYPAC 190

  Fly   220 VALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVE-SDWALSFVVPGIIIAAVGFLLFLF 283
            ..:..:|....:|..:.......:..|.::...:|...|: |.|:..|.|.|    :.|.:.::|
Frog   191 HGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYG----SFGIMWYMF 251

  Fly   284 LV----DQPEIVGCYPQAGQHERRVANESDVEQDDEEQVRHNDAEINYRSAPTERTPILPRSQPE 344
            .:    :.|.|   :|...:.|::..         ||.:..:...:|            |.::.:
Frog   252 WILVSYESPAI---HPTISEEEKKYI---------EESIGESTGLMN------------PMAKFK 292

  Fly   345 AVPRGRGRPISLIDALFIPGVVEFSLCLFFTKLVSYTFMYWL---PLYIQKSSTLGPELS----- 401
            |..|      ....::.:..::..:.|.      |:||...|   |.|.::  ..|.|:|
Frog   293 APWR------KFFTSMPVYAIIVANFCR------SWTFYLLLISQPAYFEE--VFGFEISKVGLL 343

  Fly   402 -----ADLSTLFDVGGILGAIAAGYLSDVSGMSATVCTGML----FVASPILLMYQQYG-ALSMT 456
                 ..::.:..:||.:    |.:|.....||.|....|:    |.....||:...|. :..:.
Frog   344 SALPHLVMTIIVPIGGQI----ADFLRTKRIMSTTNVRKMMNCGGFGMEATLLLVVGYSHSRGVA 404

  Fly   457 ISIVLLIV--VGIFVNGPYALITTSVSAELGQHSSLEGNANAL-------ATVTAIIDGTGSIGA 512
            ||.::|.|  .|..::|                    .|.|.|       :.:..|.:|.|::..
Frog   405 ISFLVLAVGFSGFAISG--------------------FNVNHLDIAPRYASILMGISNGVGTLSG 449

  Fly   513 AVGPLLAGLI----STAGWQYVFHMLIAADIIAMVLLGRLVF 550
            .|.||:.|.:    :...|||||  |||    ::|..|.::|
Frog   450 MVCPLIVGAMTKHKTREEWQYVF--LIA----SLVHYGGVLF 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS16	NP_726048.1	UhpC	84..545	CDD:225180	94/498 (19%)
MFS16	NP_726048.1	MFS	139..549	CDD:119392	84/445 (19%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	97/509 (19%)
		MFS	67..490	CDD:119392	96/504 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910