Protein Alignment MFS16 and SLC37A2

DIOPT Version :10

• Sequence 1: NP_726048.1
• Gene: MFS16 / 37427
• FlyBaseID: FBgn0034611
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 261/496 - (52%)
• Similarity: 324/496 - (65%)
• Gaps: 31/496 - (6%)

  Fly    80 RDLLYKMSVFVLTFLAYACYHMCRKPISVVKSVLQGNCSTALAASGQD--------CGYAPFDVP 136
            ||..::..:.:||||.||||||.|||||:|||.|..|||..:......        |.:||||..
Human    17 RDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKD 81

  Fly   137 DATTLFGMLDSAFLFSYAIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYF 201
            :...|.|.:|:|||.:|||.||.||...||:.|||:||.||:|:|:||.:||:....|||.||||
Human    82 NYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYF 146

  Fly   202 IIVQIFAGIFQTTGWPGVVALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVESDWALSF 266
            :::|:..|:.||||||.||..||.||||.|||.|.||||||||:|||||:|||..:|...|.|||
Human   147 VVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQWGLSF 211

  Fly   267 VVPGIIIAAVGFLLFLFLVDQPEIVGCYPQAGQHERRVANESDVEQDDEE---QVRHNDAEINYR 328
            :|||||.|.:|.:.||||::.||.|.|.|.  ||....|...|..:|...   .:|.:..|...:
Human   212 IVPGIITAVMGVITFLFLIEHPEDVDCAPP--QHHGEPAENQDNPEDPGNSPCSIRESGLETVAK 274

  Fly   329 SAPTERTPILPRSQPEAVPRGRGRPISLIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYIQKS 393
            .:..      |..:|.|        ||...||.|||||||||||.|.|||||||:|||||||...
Human   275 CSKG------PCEEPAA--------ISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANV 325

  Fly   394 STLGPELSADLSTLFDVGGILGAIAAGYLSDVSGMSATVCTGMLFVASPILLMYQQYGALSMTIS 458
            :....:.:.|||||||||||:|.|.||.:||.:...||.|..||.:|:|::.:|...|...:..|
Human   326 AHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGIASS 390

  Fly   459 IVLLIVVGIFVNGPYALITTSVSAELGQHSSLEGNANALATVTAIIDGTGSIGAAVGPLLAGLIS 523
            ||:||:.|..||||||||||:|||:||.|.||:|||.||:|||||||||||||||:|||||||||
Human   391 IVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLIS 455

  Fly   524 TAGWQYVFHMLIAADIIAMVLLGRLVFKEFAA----LRRAS 560
            ..||..||:|||:||::|.:||.|||:||..|    |.|.|
Human   456 PTGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGS 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS16	NP_726048.1	MFS_SLC37A1_2	85..552	CDD:340902	253/477 (53%)
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	253/477 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		6/23 (26%)