Protein Alignment MFS16 and SLC17A4

DIOPT Version :10

• Sequence 1: NP_726048.1
• Gene: MFS16 / 37427
• FlyBaseID: FBgn0034611
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 104/503 - (20%)
• Similarity: 184/503 - (36%)
• Gaps: 115/503 - (22%)

  Fly   114 QGNCSTALAASGQDCGYAPFDVPDATT------------------------------LFGMLDSA 148
            |.|.|.|:.|...:.  ||...|:|:|                              :.|::.|:
Human    54 QMNLSIAIPAMVNNT--APPSQPNASTERPSTDSQGYWNETLKEFKAMAPAYDWSPEIQGIILSS 116

  Fly   149 FLFSYAIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYFIIVQIFAGIFQT 213
            ..:...:|...||:||.....:|.:..|:.::...|....:|..:.:..|   |:::|..||.|.
Human   117 LNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAANAGVALL---IVLRIVQGIAQV 178

  Fly   214 TGWPGVVALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVES-DWALSFVVPGIIIAAVG 277
            ....|..::..:|....:|..:..|..|.:.:|:.:..|......:: .|...|.:.|.|..|..
Human   179 MVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLLCQTIGWPYVFYIFGGIGCACC 243

  Fly   278 FLLFLFLVDQPEIVGCYPQAGQHERRVANESDVEQDDEEQVRHNDAEINYRSAPTERTPILPRSQ 342
            .|.|..:.|.|                             |.|     .:.||..:|..:...:|
Human   244 PLWFPLIYDDP-----------------------------VNH-----PFISAGEKRYIVCSLAQ 274

  Fly   343 PEAVPRGRGRPI-SLIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYIQKSSTLGPEL--SADL 404
            .:..| |...|| ::|.:|.:..::....|.::   :.||.|.:.|.||  ||.|...|  |..|
Human   275 QDCSP-GWSLPIRAMIKSLPLWAILVSYFCEYW---LFYTIMAYTPTYI--SSVLQANLRDSGIL 333

  Fly   405 STLFDVGGILGAIAAGYLSD----------VSGMSATVCTGMLFVASPILLMYQQYGALSMTISI 459
            |.|..|.|.:..|..|.|:|          ::........|:||.:..::.:.....:.|||::.
Human   334 SALPFVVGCICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWVRSSHSMTMTF 398

  Fly   460 VLLIVVGIFVNGPYALITTSVSAELGQHSSLEGNANALATVTAIIDGT----GSIGAAVGPLLAG 520
                           |:.:|..:...:..:|....:.....|..:.|.    ..|..|:.|..||
Human   399 ---------------LVLSSAISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAG 448

  Fly   521 LI----STAGWQYVFHMLIAADIIAMV---LLGRLVFKEFAALRRASH 561
            ..    |..||:.||.:..|.:|..:|   :.||...:::|..:..:|
Human   449 FFISQDSEFGWRNVFLLSAAVNISGLVFYLIFGRADVQDWAKEQTFTH 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS16	NP_726048.1	MFS_SLC37A1_2	85..552	CDD:340902	102/492 (21%)
SLC17A4	NP_005486.1	MFS_SLC17	40..481	CDD:340876	100/486 (21%)