DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS16 and slc37a3

DIOPT Version :9

Sequence 1:	NP_726048.1	Gene:	MFS16 / 37427	FlyBaseID:	FBgn0034611	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_002941656.2	Gene:	slc37a3 / 100485507	XenbaseID:	XB-GENE-995744	Length:	502	Species:	Xenopus tropicalis

Alignment Length:	539	Identity:	184/539 - (34%)
Similarity:	281/539 - (52%)	Gaps:	69/539 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 DVPFGIRAVQRLS--RQCCTRF-HARRDLLYKMSVFVLTFLAYACYHMCRKPISVVKSVLQ---- 114
            |.|.|.|   ||:  |.|.::: |      :.::||:|||.:||..|..||..|.||..:.
Frog     2 DFPVGSR---RLAGRRGCFSQYSH------HHVAVFLLTFFSYALLHASRKAFSNVKVSISSQWT 57

  Fly   115 --GNCSTALAASGQDC-GYAPF-DVPDATTLFGMLDSAFLFSYAIAMFASGFVAERVSLRYFLSM 175
              |..||.:....:.. |...| |...||...|:||:.|||:||:.:|.||.:.:|:::|..|:.
Frog    58 PLGLNSTYIVLPNETWNGNTLFPDTKTATIFLGLLDTIFLFAYAVGLFISGIIGDRLNMRLVLTF 122

  Fly   176 GMILTGVFTYMFG-IARTSNIHSLWYFIIVQIFAGIFQTTGWPGVVALVGRWFGKSKRGLIFGIW 239
            ||..:.:..::|| :......::..::.:|.|..|:.|:||||.|||::|.|||||.||.:||:|
Frog   123 GMCSSAITMFVFGTLTEWLRFYNKVFYCLVWILNGLLQSTGWPCVVAVMGNWFGKSGRGFVFGLW 187

  Fly   240 NSHTSIGNILGTLIAAHYVESDWALSFVVPGIIIAAVGFLLFLFLVDQPEIVGCYPQAGQHER-R 303
            ::..|:|||||..:|:..::..:..:|:|...:..|.|.::|..||..|:.:| .|:.|:.|. |
Frog   188 SACASVGNILGAFLASSVLQYGYEYAFLVTASVQFAGGIIIFFGLVTSPKELG-LPETGEGETDR 251

  Fly   304 VANESDVEQ------DDEEQVRHNDAEINYR-------SAPTERTPILPRSQPEAVPRGRGRPIS 355
            .|.|....:      ||      .|.|.||.       |||                    :.|.
Frog   252 AAREEGANRPLISGNDD------GDDESNYSIQSDDVVSAP--------------------KAIG 290

  Fly   356 LIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYIQKSSTLGPELSAD-LSTLFDVGGILGAIAA 419
            .:.|..:|||:.:||.....|||:|:|.:|||.|: .::....|..|| ||..:|:|||:|....
Frog   291 FVQACCLPGVLLYSLAYACLKLVNYSFFFWLPFYL-SNNFKWKEAEADQLSIWYDIGGIIGGTVQ 354

  Fly   420 GYLSDVSGMSATVCTGMLFVASPILLMYQQYGALSMTISIVLLIVVGIFVNGPYALITTSVSAEL 484
            |.:||:..|.:.|.|..|..|...|..| .:......|:..::.|.|.||.||..:|::::||:|
Frog   355 GLISDLMKMRSPVLTVSLLCAVGSLFGY-SHSPNDKVINAFIMSVTGFFVGGPSNMISSAISADL 418

  Fly   485 GQHSSLEGNANALATVTAIIDGTGSIGAAVGPLLAGLISTA-GWQYVFHMLIAADIIAMVLLGRL 548
            |:...:.|::.||||||.|:|||||||||:|..|..||..| .|.:||:..|....:.:|.:..|
Frog   419 GRQEMVRGSSEALATVTGIVDGTGSIGAALGQTLVSLIQNALSWMWVFYFFIFMICMTVVFMVPL 483

  Fly   549 VFKE---FAALRRASHRIR 564
            |.:|   :...||||...|
Frog   484 VVRETRDWLRQRRASRLAR 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS16	NP_726048.1	UhpC	84..545	CDD:225180	167/485 (34%)
MFS16	NP_726048.1	MFS	139..549	CDD:119392	147/426 (35%)
slc37a3	XP_002941656.2	MFS_SLC37A3	24..484	CDD:340900	167/488 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D292288at33208
OrthoFinder	1	1.000	-	-		FOG0000756
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010