DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt49C1 and ATG26

DIOPT Version :9

Sequence 1:	NP_001036565.1	Gene:	Ugt49C1 / 37421	FlyBaseID:	FBgn0034605	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_013290.1	Gene:	ATG26 / 850886	SGDID:	S000004179	Length:	1198	Species:	Saccharomyces cerevisiae

Alignment Length:	517	Identity:	105/517 - (20%)
Similarity:	185/517 - (35%)	Gaps:	152/517 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVT---------AF 62
            ||||..|:                     :.....:.||.:.|::.||||.::|         :.
Yeast   742 FGLLTIGS---------------------RGDVQPYIALGKGLIKEGHQVVIITHSEFRDFVESH 785

  Fly    63 SLEKEQLGSNYTEILIEPV----------------YDFWHDVKLNFGAQHLFELTRMTNYDFLKM 111
            .::.|::..|..|::...|                :..|.|..|    |..:|:.....:|.|
Yeast   786 GIQFEEIAGNPVELMSLMVENESMNVKMLREASSKFRGWIDALL----QTSWEVCNRRKFDIL-- 844

  Fly   112 LE----IIGLKTTEHALRQP----------KVRSLIHA----EQKEG----VFDLLLAEQFYQEA 154
            :|    ::|:..|| ||:.|          :.|:..||    :||.|    ....:|.|..:.:.
Yeast   845 IESPSAMVGIHITE-ALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKG 908

  Fly   155 FLALAHLYKIPVVTTSTLGYEN-HMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFYED 218
            .....:.::   |.|..||..| .:.|...:...::..|..|.|..|   |.|.|:.:...|.:|
Yeast   909 ISGQVNKWR---VETLGLGKTNLFLLQQNNVPFLYNVSPTIFPPSID---FSEWVRVTGYWFLDD 967

  Fly   219 MDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHI 283
            ....     |..|..:||.....::..|:.::... |:::.|       |:...:|:|..
Yeast   968 KSTF-----KPPAELQEFISEARSKGKKLVYIGFG-SIVVSN-------AKEMTEALVEA----- 1014

  Fly   284 YPPKPLPADMQALLD-GATEGAIFFSLGSNVQSK---DMPVEMLRLFLQVFGSLKQRVLWKFEDE 344
                .:.||:..:|: |.:|     .||.....|   |:|..:|
Yeast  1015 ----VMEADVYCILNKGWSE-----RLGDKAAKKTEVDLPRNIL--------------------- 1049

  Fly   345 SISQLPDNVMVRKWL-PQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKA 408
            :|..:|.:     || ||.|...|        |||...|...:...:|.:..||:.||.....:.
Yeast  1050 NIGNVPHD-----WLFPQVDAAVH--------HGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRV 1101

  Fly   409 VLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRV-SDIFRDRPLEPRKSAVY-WIEY 468
            ...|..|:|  :.:..:.|..:|.....|...|:....: ..|.::..::...||:| .:||
Yeast  1102 EDIGVGIAL--KKLNAQTLADALKVATTNKIMKDRAGLIKKKISKEDGIKTAISAIYNELEY 1161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	100/502 (20%)
Ugt49C1	NP_001036565.1	UDPGT	37..498	CDD:278624	100/487 (21%)
ATG26	NP_013290.1	GRAM	194..>239	CDD:214725
		PH-GRAM1_AGT26	219..335	CDD:275402
		PH-GRAM2_AGT26	581..673	CDD:275403
		YjiC	739..1168	CDD:224732	105/517 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000