DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt49C1 and UGT76C1

DIOPT Version :9

Sequence 1:	NP_001036565.1	Gene:	Ugt49C1 / 37421	FlyBaseID:	FBgn0034605	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_196206.1	Gene:	UGT76C1 / 830472	AraportID:	AT5G05870	Length:	464	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	120/566 - (21%)
Similarity:	198/566 - (34%)	Gaps:	189/566 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMV-TAFSLEKEQ 68
            :||.|.|.|.:...|:||   ||                     |...|..:|:: |.|:..|
plant    10 ILFPLPLQGCINPMLQLA---KI---------------------LYSRGFSITIIHTRFNAPK-- 48

  Fly    69 LGSNYTEILIEPVYDFWHDVKLNFGAQH--------LFELTRMTN---YDFLKMLEIIGLKTTEH 122
             .|::      |::.|   :::..|...        |.:||.:.|   ..|.:.|..:...:::.
plant    49 -SSDH------PLFTF---LQIRDGLSESQTQSRDLLLQLTLLNNNCQIPFRECLAKLIKPSSDS 103

  Fly   123 ALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITP 187
            .....|:..:|  :....||...:||.|....|:..|:.:..
plant   104 GTEDRKISCVI--DDSGWVFTQSVAESFNLPRFVLCAYKFSF----------------------- 143

  Fly   188 WSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFP---KMDAVAREFFGPVLTEVPKVKH 249
              |:.|..:|...|..||. |.:|.|      |.|:..||   |.|          |:.:.....
plant   144 --FLGHFLVPQIRREGFLP-VPDSEA------DDLVPEFPPLRKKD----------LSRIMGTSA 189

  Fly   250 MERQISVMLLNSHAPLTTARPTVDAMV-----------------------PVGGMHIYPPKPLPA 291
            ..:.:...||..   |...:|....:|                       |:|..||:   .:||
plant   190 QSKPLDAYLLKI---LDATKPASGIIVMSCKELDHDSLAESNKVFSIPIFPIGPFHIH---DVPA 248

  Fly   292 DMQALLD-----------GATEGAIFFSLGS--NVQSKDMPVEMLRLFLQVFGSLK---QRVLWK 340
            ...:||:           ..|...::.||||  ::...|        ||::...|:   |..||.
plant   249 SSSSLLEPDQSCIPWLDMRETRSVVYVSLGSIASLNESD--------FLEIACGLRNTNQSFLWV 305

  Fly   341 FEDES------ISQLPDNVM--------VRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVP 391
            ....|      |..||...|        :.:|.||.|:||||....|:||.|...|.|.:...||
plant   306 VRPGSVHGRDWIESLPSGFMESLDGKGKIVRWAPQLDVLAHRATGGFLTHNGWNSTLESICEGVP 370

  Fly   392 MLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYK---ENVQRVSDIFRD 453
            |:.:|...||.:|. :.:...:.:.:|.:.   .|.|..:::.:..:..:   |.::....:.||
plant   371 MICLPCKWDQFVNA-RFISEVWRVGIHLEG---RIERREIERAVIRLMVESKGEEIRGRIKVLRD 431

  Fly   454 RPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFV 499
               |.|:|.         .:|.|..||  ||      .|:|.|:.:
plant   432 ---EVRRSV---------KQGGSSYRS--LD------ELVDRISII 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	113/549 (21%)
Ugt49C1	NP_001036565.1	UDPGT	37..498	CDD:278624	110/531 (21%)
UGT76C1	NP_196206.1	Glycosyltransferase_GTB_type	2..451	CDD:299143	117/558 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050